Memory impairments observed after a half night sleep restriction are not mediated by working memory, attention, or inhibitory control mechanisms [0.03%]
半夜间睡眠剥夺引起的记忆损害并非通过工作记忆、注意力或抑制控制机制产生
Pim R A Heckman,Robbert Havekes,Arjan Blokland
Pim R A Heckman
Sleep restriction is a growing issue in our modern society and thus it is crucial to uncover its neurocognitive consequences. Especially declarative memory is negatively affected by sleep loss due to its critical dependence on the hippocamp...
Memory formation following appetitive conditioning is variably dependent on retinoid signaling [0.03%]
视黄醇信号传递可变性地影响条件刺激后的记忆形成
Raymond K Wong,Gaynor E Spencer
Raymond K Wong
Retinoic acid (RA), the metabolite of Vitamin A, plays an important role in central nervous system development and regeneration, as well as learning and memory in vertebrates. We have previously shown that RA signaling is also important for...
Glutamate receptor expression in the PL-BLA circuit is associated with susceptibility to showing the PTSD-like phenotype [0.03%]
PL-BLA神经回路中的谷氨酸受体的表达与易出现类似创伤后应激障碍表型有关
Charlotte S Rye,Amy L Milton
Charlotte S Rye
While many individuals experience traumatic events during their lifetimes, only some go on to develop post-traumatic stress disorder (PTSD). This susceptibility and resilience to developing PTSD can be modelled in rodents using the stress-e...
Cortisol modulates hippocampus activation during semantic substitution in men [0.03%]
皮质醇调节男性语义替代过程中的海马激活效应
Nicole Klein,Carina Zöllner,Tobias Otto et al.
Nicole Klein et al.
In the case of incomplete episodic memory retrieval, semantic knowledge may play a vital role compared to random memory errors in filling in memory gaps (semantic substitution). Stress impairs (episodic) memory retrieval via stress hormones...
Cutting-edge RNA technologies to advance the understanding of learning and memory [0.03%]
先进的RNA技术推动学习与记忆的理解进展
Joshua William Ashley Davies,Timothy William Bredy,Paul Robert Marshall
Joshua William Ashley Davies
Following the recent emergence of RNA as a therapeutic tool, and coupled with an explosion in the development of new RNA technologies, it is rapidly becoming clear that the 21st century is the era of RNA. Neuroscience as a discipline has a ...
Kisang Eom,Donguk Kim,Jung Ho Hyun
Kisang Eom
During the processing of information in humans, activated neurons behave in a specific way. The activity of these neurons leaves traces on the neurons, such as changes in synaptic or intrinsic properties. Formation of the memory traces is a...
The impact of systemic blockade of dopamine receptors on the acquisition of two-way active avoidance in male rats [0.03%]
多巴胺受体系统性阻断对雄性大鼠二维积极回避习得的影响
L Vercammen,A Lopez-Moraga,T Beckers et al.
L Vercammen et al.
Active threat avoidance is a core aspect of adaptive and maladaptive behavior, yet its underlying mechanisms are not fully understood. Prior studies concluded that pharmacologically blocking dopaminergic receptors (DRs) disrupted avoidance ...
Benita Jin,Michael W Gongwer,Laura A DeNardo
Benita Jin
Memory retrieval involves coordinated activity across multiple brain regions. Yet how the organization of memory networks evolves throughout development remains poorly understood. In this study, we compared whole-brain functional networks t...
The infralimbic, but not the prelimbic cortex is needed for a complex olfactory memory task [0.03%]
复杂嗅觉记忆任务需要依赖前侧前边缘皮层，而非腹内侧前额叶皮层
Dahae J Jun,Rebecca Shannon,Katherine Tschida et al.
Dahae J Jun et al.
The medial prefrontal cortex (mPFC) plays a key role in memory and behavioral flexibility, and a growing body of evidence suggests that the prelimbic (PL) and infralimbic (IL) subregions contribute differently to these processes. Studies of...
Greta Leonore Balmer,Shuvrangshu Guha,Stefanie Poll
Greta Leonore Balmer
Memories are our reservoir of knowledge and thus, are crucial for guiding decisions and defining our self. The physical correlate of a memory in the brain is termed an engram and since decades helps researchers to elucidate the intricate na...