Double dissociation in the involvement of noradrenergic and endocannabinoid systems in classical and higher-order conditioning in newborn rabbits [0.03%]
新生儿兔子在经典条件反射和高阶条件反射中肾上腺素能系统和内源大麻素系统的分离作用研究
Eva-Gunnel Ducourneau,Patricia Duchamp-Viret,Giovanni Marsicano et al.
Eva-Gunnel Ducourneau et al.
Since Ivan Pavlov first demonstrated classical conditioning by pairing a neutral stimulus with a reinforcer, researchers have applied this approach to understand not only direct associations, but also more complex learning processes, such a...
An occasion for reflection: Pavlovian modulation of conditioned responding by interoceptive drug stimuli [0.03%]
值得思考的现象：内脏药物刺激对条件反应的巴甫洛夫调节
Rick A Bevins,Scott T Barrett,Jennifer E Murray
Rick A Bevins
Nearly 100 years ago, Ivan Pavlov's research into learning processes provided a framework for understanding how the brain makes behaviorally impactful associations between events. His seminal findings on excitatory and inhibitory conditioni...
Chemogenetic disruption of the hippocampus impairs gustatory preconditioning in rats [0.03%]
化学遗传破坏海马体可损害大鼠的味觉预处理作用
Mélie M Talaron,Nathan M Holmes,Guillaume Ferreira et al.
Mélie M Talaron et al.
Adaptive behavior often relies on learning associations between stimuli that were never directly paired with reinforcement. Sensory preconditioning provides a powerful paradigm to investigate such indirect learning: when neutral stimuli A a...
Corrigendum to "Dynamic regulation of neuronal vault trafficking and RNA cargo by the noncoding RNA, Vaultrc5" [Neurobiol. Learn. Memory 225 (2026) 108161] [0.03%]
“非编码RNA Vaultrc5对神经细胞vault转运及其RNA cargos的动态调节”一文的勘误通知书
Mason R B Musgrove,Laura J Leighton,Margaux Lebouc et al.
Mason R B Musgrove et al.
Published Erratum
Neurobiology of learning and memory. 2026 Jun 22:108182. DOI:10.1016/j.nlm.2026.108182 2026
Modeling the coexistence of NMDAR-dependent LTP and LTD mediated by changes in AMPAR conductance [0.03%]
基于AMPA受体电导变化的NMDA受体依赖性长时程增强和长时程抑制共存现象的模型研究
Berke Ozgur Arslan,Ismail Akturk,Neslihan Serap Sengor et al.
Berke Ozgur Arslan et al.
In this work, we develop a mathematical model that captures both the early and late phases of Long-Term Potentiation (LTP) and Long-Term Depression (LTD), incorporating NMDAR-dependent induction and changes in AMPAR conductance. The model c...
No evidence for a protein-synthesis-dependent form of long-term fear memory: Translational inhibition and neural inactivation disrupt short- and long-term memory measures to the same degree [0.03%]
没有证据表明存在一种依赖蛋白质合成的长期恐惧记忆形式：翻译抑制和神经活动阻断对短期记忆和长期记忆的破坏程度相同
S Al-Smadi,L A Rimstad,C Scavuzzo et al.
S Al-Smadi et al.
Translational inhibition has been suggested to impair long-term memory (LTM) while leaving short-term memory (STM) unaffected. However, intracranial infusions of protein synthesis inhibitors such as anisomycin (ANI), cycloheximide, and emet...
REM sleep fragmentation is associated with impaired configural threat learning [0.03%]
REM睡眠片段化与配置威胁学习受损有关
Bruna Cuccurazzu,Patrick Vizeli,Erin Natale et al.
Bruna Cuccurazzu et al.
Rapid eye movement (REM) phases of sleep are consistently disrupted after trauma and in post-traumatic stress disorder (PTSD). REM disruption impairs cued fear learning, a core element of trauma processing linked to PTSD risk and symptom pe...
Trazodone reduces sign-tracking but not goal-tracking in male Sprague Dawley rats [0.03%]
度洛西汀降低雄性Sprague Dawley大鼠的迹象追踪但不影响目标追踪
John Michael Holden,Liam Kubitschek
John Michael Holden
Sign-tracking refers to interaction with or approach of an appetitive conditioned stimulus (CS) and is a behavior with implications for cue-induced relapse in those in rehabilitation from drug use. Pharmacological options for reducing sign-...
Shorter sleep duration predicts altered next-day physiologic, behavioral, and corticolimbic responses during fear extinction recall in youth [0.03%]
睡眠时间缩短预示着青少年在下一日恐惧消退回忆期间的生理、行为和边缘叶脑区反应改变
Carmen Carpenter,Clara G Zundel,Samantha L Ely et al.
Carmen Carpenter et al.
Background: Insufficient sleep is prevalent in youth and associated with elevated anxiety risk, yet the neurobiological mechanisms linking sleep to anxiety remain poorly understood. One potential pathway involves impaired...
Ventral hippocampus and the contextual control of Pavlovian and instrumental behaviors [0.03%]
海马 ventral 与 Pavlovian 和 instrument 行为的情境控制
Samantha K Moriarty,Travis P Todd,Shauna L Parkes
Samantha K Moriarty
The purpose of the present review is to consider and integrate research that has examined the role of the ventral hippocampus (VH) in the contextual regulation of both Pavlovian and instrumental behaviors. To do so, we selectively review re...