William H Livingston,Adam L Putnam,Erin J Wamsley
William H Livingston
Like sleep, a brief period of eyes-closed waking rest following encoding can improve memory. But in addition to quantitatively strengthening memory, sleep also qualitatively transforms memory. In one example of this effect, sleep has been r...
Male spontaneously hypertensive rats demonstrate reduced goal-directed control and difficulty updating previous learning [0.03%]
雄性 SHR 大鼠表现出目标导向控制减弱和难以更新先前学习的能力
Zachary Pierce-Messick,Elif Sari,Laura H Corbit
Zachary Pierce-Messick
Habitual control of repeated behaviours is adaptive because it can allow routine behaviours to continue under conditions where cognitive capacity is limited or burdened. However, the impact that cognitive demand has on behavioural control h...
E Stewart,T J Ryan
E Stewart
Responding appropriately to both internal and external factors to maintain homeostasis is key to survival in the dynamic environment we live in. Memory a is highly adaptive brain function which enables organisms to interact efficiently with...
The role of post-learning EEG theta/beta ratio in long-term navigation performance [0.03%]
关于后学习EEGtheta/beta比值在长期空间记忆中作用的一项研究
Roman Rozengurt,Alexandra Dolzhenko,Daniel Levy et al.
Roman Rozengurt et al.
Memory consolidation processes have been shown to benefit from modulations in brain activity, particularly theta oscillations. Our previous studies showed that increases in post-learning Theta/Beta power ratio improves subsequent performanc...
Frustrative nonreward, sucrose consumption, and the basal ganglia: Role of chemogenetic activation of projections from the nucleus accumbens to the globus pallidus internus, globus pallidus externus, and ventral pallidum [0.03%]
挫败性非奖励、糖消耗和基底神经节:脑伏核到内侧苍白球、外侧苍白球和腹侧苍白球投射的化学遗传激活的作用
Christopher W Hagen,Jessica Suárez,Mauricio R Papini
Christopher W Hagen
Mammals experience negative emotions after the unexpected reduction in reward magnitude-called frustrative nonreward (FNR). The neurobiological mechanisms activated in response to unexpected reward downshift could shed light on loss-induced...
Increasing degradation-independent linear polyubiquitin in the hippocampus enhances memory in young adult but not aged rats [0.03%]
增加海马体中与退行无关的线性泛素增强年轻成年而非老年大鼠的记忆力
Morgan B Patrick,Natalie J Preveza,Yeeun Bae et al.
Morgan B Patrick et al.
Age-related memory loss affects approximately 40% of the world's population after the age of 65 and is a significant risk factor for the development of dementia and Alzheimer's Disease (AD). Numerous studies have reported that late in life ...
The interval between conditional stimulus onset and unconditional stimulus onset, not training-to-test interval, determines patterns of immediate early gene expression in the anterior retrosplenial cortex [0.03%]
在前部回神回皮质中,条件性刺激和非条件性刺激之间的间隔,而不是训练与测试之间的时间间隔决定了立即早期基因表达的模式
Sydney Trask,Jaden B Brooks,Sean Warner
Sydney Trask
Prior work has found that the retrosplenial cortex (RSC) is necessary for formation and retrieval of trace, but not delay, fear conditioning. However, more recently, others have demonstrated that activity in the retrosplenial cortex is nece...
The REM effect: How sleep stages influence learning strategies in complex reward-based decision-making [0.03%]
REM效应:睡眠阶段如何影响复杂基于奖赏的决策学习策略
Eleni Kavaliotis,Justin Mahlberg,Daniel Bennett et al.
Eleni Kavaliotis et al.
Model-free (MF) and model-based (MB) learning strategies are complementary decision-making processes used in evaluating choices with potential rewards. Disorders involving compulsive behaviours (e.g., substance use, gambling) are suggested ...
The effect of biperiden on episodic memory: Testing the serial position effect [0.03%]
双吡咯烷二环己胺对情景记忆的影响:检验系列位置效应
Arjan Blokland,Laura Borghans,Michal Hasselmo et al.
Arjan Blokland et al.
Biperiden (BIP), a muscarinic type 1 (M1) receptor antagonist, has been proposed as a pharmacological model for episodic memory impairment in mild cognitive impairment (MCI) and early stages of Alzheimer's disease (AD). Understanding the ef...
Hormonal regulation of behavioral and emotional persistence: Novel insights from a systems-level approach to neuroendocrinology [0.03%]
从神经内分泌学系统水平方法获得的行为和情感持久性激素调节的新见解
Meenakshi M Asokan,Annegret L Falkner
Meenakshi M Asokan
Gonadal sex steroid hormones regulate internal states (Gutierrez-Castellanos et al., 2022), social drive (Guthman and Falkner, 2022), perception of external cues (Li and Dulac, 2018), and learning and memory (Taxier et al., 2020). Fluctuati...