Are the principles of Pavlovian conditioning in insects conserved with those in mammals? [0.03%]
昆虫的巴甫洛夫条件反射原理与哺乳动物的相同吗？
Makoto Mizunami
Makoto Mizunami
Pavlovian conditioning, in which a relatively insignificant stimulus (the conditioned stimulus, CS) is paired with a biologically significant stimulus (the unconditioned stimulus, US), is a ubiquitous form of associative learning found in m...
Primary auditory cortex activity during early retrieval supports later extinction learning [0.03%]
初级听觉皮层活动在早期检索期间支持后期消退学习
Nicole B Cook,Sadie May Wasberg,Tempestuous G Henneghan et al.
Nicole B Cook et al.
Emotional flexibility-the ability to update threat associations when contingencies change-is essential for adaptive behavior, yet the underlying cortical mechanisms remain unclear. Here, we used chemogenetic inhibition of primary auditory c...
Adolescent stress exposure induces persistent, sex-specific cognitive deficits [0.03%]
青春期应激暴露引起持久的、性别特异性的认知缺陷
Abigail Yap Flores,Nolee V Bugarin,Adolfo Torres et al.
Abigail Yap Flores et al.
Exposure to stress or adversity during adolescence has been shown to produce both short-term and long-lasting effects on cognitive functions. Diminished learning and memory, reduced attention, and impaired decision making in adulthood are s...
Transplantation of medial ganglionic eminence cells rescues early-life stress-induced social and cognitive impairments in postnatal mice [0.03%]
中隔神经节瘤细胞移植改善产后小鼠早期生活压力引起的社交和认知缺陷
Lanyan Lin,Yongxing Lai,Ainong Mei et al.
Lanyan Lin et al.
During the critical window of early development, exposure to stress has been demonstrated to impair brain function, thereby elevating the likelihood of subsequent social and cognitive impairments. In our study, we have developed a reliable ...
How environmental enrichment influences conditioned taste aversion: A case of behavioral tagging [0.03%]
环境丰富度影响条件性味道厌恶的机理：一种行为标记的情况
Beatriz Gutiérrez-Vera,Gerardo R Perera-Murcia,Martha L Escobar
Beatriz Gutiérrez-Vera
Exposure to environmental enrichment (EE) has demonstrated a remarkable ability to modulate cognitive processes. These effects have been associated with brain-derived neurotrophic factor (BDNF), a protein recognized for regulating synaptic ...
Jake R Embrey,Kelly G Garner,Julyani Salim et al.
Jake R Embrey et al.
Pavlovian stimuli signalling potential punishment and reward have powerful effects on instrumental behaviours. For example, a cue associated with punishment will suppress well-learned instrumental responses. However, the degree to which Pav...
Involvement of serotonin receptors in destabilization and re-stabilization of retrieved context and food-aversion memory in terrestrial snail Helix lucorum [0.03%]
五羟色胺受体参与了陆生蜗牛Helix lucorum内源性提取出的上下文和食物恶习记忆的去稳定化和重新稳定化过程
Alena B Zuzina,Aliya Kh Vinarskaya,Pavel M Balaban
Alena B Zuzina
The necessity for serotonin participation in memory reconsolidation in snails was demonstrated previously. So far, no research has addressed the involvement of serotonin receptors in retrieval-induced destabilization and re-stabilization of...
Hunger alters approach-avoidance behaviours differently in male and female mice [0.03%]
饥饿通过不同方式改变小鼠的男女趋避行为
Roberta G Anversa,Gemma Goldstein,Ibrahim Syed et al.
Roberta G Anversa et al.
Background: The decision about whether to approach or avoid a reward while under threat requires balancing competing demands. Sex-specific prioritisations (e.g. mating, maternal care), or generalised prioritisations (e.g....
Jasmin A Strickland,Joseph M Austen,Rolf Sprengel et al.
Jasmin A Strickland et al.
The GRIA1 subunit of the AMPA receptor, encoded by the GRIA1 gene, has been implicated in schizophrenia. Schizophrenia is associated with impairments in attention that may lead to other symptoms due to a failure to learn selectively (e.g., ...
The role of retinoids in memory reconsolidation and extinction following appetitive conditioning [0.03%]
视黄醇在 appetitive conditioning 后记忆再巩固和消退中的作用
Justin Wimmer,Zakariah Ibrahim,Gaynor E Spencer
Justin Wimmer
Retinoic acid, the active metabolite of vitamin A, is an important signaling molecule during vertebrate synaptic plasticity and learning and memory. We have shown that it also plays a role in long-term memory formation following both operan...