Mario Michiels,David Luque,Ignacio Obeso
Mario Michiels
Habitual behavior is thought to emerge with extended training and reduced sensitivity to outcome devaluation. However, little is known about how habit-like oculomotor responses adapt when devaluation is implicit or embedded within a previou...
Sex differences and the influence of sex hormones on fear extinction and exposure therapy across the lifespan: A systematic review of studies in rodents and humans [0.03%]
一生中性别差异和性激素对恐惧消退及暴露疗法的影响:啮齿类动物与人类相关研究的系统回顾
Jodie E Pestana,Fionn Dunphy-Doherty,Madison Brooke et al.
Jodie E Pestana et al.
Fear extinction is a laboratory model that informs the mechanisms of exposure therapy for anxiety disorders. Although knowledge on fear extinction is primarily based on males, converging research shows that fear extinction and exposure ther...
Intrinsic excitability changes in amygdala neurons following observational fear conditioning in mice [0.03%]
小鼠观察性恐惧条件作用后的杏仁核神经元固有兴奋性变化
Eun-Hwa Hong,Yang In Kim,Young-Beom Kim et al.
Eun-Hwa Hong et al.
Observational fear conditioning (OFC) is used to study the social transmission of aversive information within a social context. In a typical experiment, observers exhibit defensive responses after witnessing a demonstrator's reaction to rep...
Double dissociation between the involvement of Gadd45α and Gadd45β/γ in the perirhinal cortex and hippocampus of male rats for object memory [0.03%]
Gadd45α和Gadd45β/γ在雄性大鼠腹侧纹状体和海马体与物体记忆形成中的不同作用
Krista A Mitchnick,Samantha D Creighton,Karanveer S Johal et al.
Krista A Mitchnick et al.
The GADD45 family of proteins (GADD45α, GADD45β, GADD45γ) has been implicated in DNA demethylation and long-term memory formation. Recently, conflicting findings have emerged surrounding the involvement of Gadd45α in various object reco...
Long-lasting avoidance induced by repeated stimulation of the rostromedial tegmental nucleus [0.03%]
反复刺激背侧中脑导水管核诱导的持久回避行为
J R Watson,M D Lopez De Leon,E L Carlson et al.
J R Watson et al.
Adaptive decision-making requires the ability to weigh the relative costs versus the benefits of our actions and to flexibly respond to changing environmental contingencies. While midbrain dopamine (DA) has been a major focus of study for i...
Accelerated maturation of fear regulation systems in infant rats following early life inflammation [0.03%]
早期生命期炎症可加速幼年大鼠恐惧调节系统的成熟
Tayla B McCutcheon,Sara M Simenson-Braun,Rick Richardson
Tayla B McCutcheon
Early life stress is a well-established risk factor for neuropsychiatric and neurodevelopmental disorders, yet the mechanisms underlying this lifelong vulnerability remain unclear. One possibility is that early stress exposure disrupts the ...
Philip Jean-Richard-Dit-Bressel
Philip Jean-Richard-Dit-Bressel
Acute exercise after motor practice enhances generalized skill learning, corticospinal excitability and intermuscular coherence in older adults [0.03%]
急性运动后进行肌肉训练可以增强老年人的技巧学习、皮质脊髓兴奋性以及肌间相干性
Jonas Rud Bjørndal,Lasse Jespersen,Rasmus Dam Wiedemann et al.
Jonas Rud Bjørndal et al.
While high-intensity aerobic exercise after motor practice enhances learning in young adults, its effects on older adults remain unknown. This study investigates whether high-intensity exercise after motor skill practice enhances memory con...
Analysis of neural plasticity genes' expression in fish brain reveals the basis of individual differences in learning [0.03%]
鱼类大脑神经可塑性基因表达的分析揭示了学习个体差异的基础
Elia Gatto,Elisa Samorì,Elena Frigato et al.
Elia Gatto et al.
Individual differences in cognition have been historically recognized in humans, and recent evidence suggests that such variation is widespread across the animal kingdom. Despite its importance for individuals' behaviour and fitness, the bi...
The mechanisms of memory traces storage and interaction in snails: Role of DNA methylation and protein synthesis [0.03%]
甲基化和蛋白质合成在蜗牛记忆痕迹存储和交互作用中的功能研究
Vladimir P Nikitin,Svetlana V Solntseva,Pavel V Nikitin
Vladimir P Nikitin
Understanding the molecular mechanisms underlying the storage and interaction of different memory traces remains an important, yet underexplored, topic in neurobiology. We addressed this using grape snails trained to reject two food-conditi...