The gut-brain-mitophagy axis: Urolithin A as a transcriptional activator of Parkin in Alzheimer's and Parkinson's diseases [0.03%]
肠-脑-线粒体自噬轴：白石脂酸通过激活帕金蛋白表达治疗阿尔茨海默病和帕金森病
Mustafa M Shokr,Mohamed N Fawzy
Mustafa M Shokr
Mitochondrial dysfunction is a cardinal, causative, and convergent hallmark in both Alzheimer's disease (AD) and Parkinson's disease (PD). However, therapeutics that target the process of mitophagy, the selective removal of damaged mitochon...
Phenotypic screening for small molecules that lower PrP in cultured cells [0.03%]
用于降低培养细胞中PrP的小分子筛选研究
Jeannine A Frei,Andrew G Reidenbach,Leo M H Xu et al.
Jeannine A Frei et al.
Prion protein (PrP) lowering is a validated therapeutic hypothesis in prion disease. To identify small molecules that reduce PrP levels, we performed phenotypic screening in cultured cells. To prioritize PrP specificity in our primary scree...
Advancing molecular and cellular neuroscience: Vision and priorities from the new editor-in-chief [0.03%]
分子与细胞神经科学的进展：新主编的愿景和优先事项
Bonnie L Firestein
Bonnie L Firestein
Apolipoprotein E in Alzheimer's disease: A review of APOE receptors, signalling pathways and therapeutic opportunities [0.03%]
载脂蛋白E在阿尔茨海默病中的作用：载脂蛋白E受体、信号通路及治疗机会综述
Saravanan Jayaram,Vigneshwaran Easwaran,Divakar Selvaraj et al.
Saravanan Jayaram et al.
Apolipoprotein E, a glycoprotein, is one of the strongest genetic risk factors for late-onset Alzheimer's disease. APOE is involved in the transport and metabolism of cholesterol, phospholipids and other lipids, synaptic function and neuroi...
Inadvertent p75NTR signaling might cause inconsistencies in the neuroprotection offered by mesenchymal stem cells [0.03%]
意外的p75NTR信号可能造成间充质干细胞神经保护效应的不一致性
Krithika Iyer,Sreelakshmi Kokkatt Balachandran,Preeja Chandran et al.
Krithika Iyer et al.
Bone marrow-derived mesenchymal stromal cells (BMSCs) have been shown to enhance regeneration and repair, even in challenging neurological conditions such as spinal cord injury (SCI). However, their clinical application for SCI remains inco...
Corrigendum to "Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents" [Mol. Cell. Neurosci. Volume 90, July 2018, Pages 49-59] [0.03%]
缩略图：I型糖尿病啮齿动物皮质线粒体功能下降及电子传递复合物II介导的H2O2产生_correction
Subir Roy Chowdhury,Jelena Djordjevic,Ella Thomson et al.
Subir Roy Chowdhury et al.
Published Erratum
Molecular and cellular neurosciences. 2026 Jun 19:104099. DOI:10.1016/j.mcn.2026.104099 2026
Sleep deprivation and hippocampal integrity: Oxidative stress mediated neuronal, memory and behavioral alterations and the restorative role of sleep recovery [0.03%]
睡眠剥夺与海马完整性：氧化应激介导的神经元、记忆和行为改变及恢复睡眠的修复作用
Konakanchi Suresh,Venkateswarlu Raavi,Vinutha Shankar et al.
Konakanchi Suresh et al.
Sleep is a vital physiological process essential for maintaining neural homeostasis, cognitive function, behavior, and health. Sleep deprivation (SD) is an increasing public health concern, largely driven by modern lifestyles and occupation...
Stress-induced neuroinflammation and synaptic dysregulation: Linking HPA axis to glutamate and NMDA receptors [0.03%]
应激诱导的神经炎症及突触调节异常：下丘脑-垂体-肾上腺轴与谷氨酸和NMDA受体之间的联系
Akhil Sharma,Thakur Gurjeet Singh
Akhil Sharma
Chronic stress is a major risk factor for psychiatric and neurological disorders, operating through interconnected molecular cascades that link neuroendocrine dysfunction to synaptic pathology. This review mechanistically examines how stres...
Occurrence of neuronal dysfunction in mice with virus- or toxic-induced lesions in the central nervous system [0.03%]
中枢神经系统病毒或毒性损伤小鼠的神经元功能障碍发生率
Martin Dembowski,Laura Burigk,Wolfgang Baumgärtner et al.
Martin Dembowski et al.
Diseases of the central nervous system (CNS) often include neuronal damage. This study examined proteins crucial to apoptosis and neuronal signalling for identifying causes of neuronal dysfunction in two animal models: Theiler's murine ence...