Chronic kidney disease trajectories in lupus nephritis: Is progression unavoidable? [0.03%]
狼疮性肾炎患者的慢性肾脏病进展不可避免吗?
Gabriella Moroni,Martina Uzzo,Marta Calatroni et al.
Gabriella Moroni et al.
Objective: To characterize trajectories of chronic kidney disease (CKD) in lupus nephritis (LN) and identify predictors of CKD progression. Methods: ...
PPAR-γ dysregulation links NF-κB activation and Nrf2-driven antioxidant responses in axial spondyloarthritis: A pilot study [0.03%]
NF-κB激活与Nrf2介导的抗氧化反应在轴向脊柱关节炎中的联系:PPAR-γ异常的链接:一项初步研究
Giuseppe Lopalco,Giuseppe Carota,Nicolò Musso et al.
Giuseppe Lopalco et al.
Background: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the axial skeleton. Expression studies support a role for inflammatory and immunomodulatory pathways in disease onset and p...
Beyond screening for pulmonary arterial hypertension: The DETECT score is a potential promising prediction tool for all-cause mortality in systemic sclerosis: Analysis from the EUSTAR database [0.03%]
超越肺动脉高压筛查:DETECT评分可能是系统性硬化症全因死亡率的潜在预测工具——来自EUSTAR数据库的分析
Florian Käs,Muriel Elhai,Mike O Becker et al.
Florian Käs et al.
Background: Systemic sclerosis (SSc) is characterized by an increased mortality. Various mortality risk factors are included in the DETECT algorithm, a screening tool for SSc-associated pulmonary arterial hypertension. We...
Impact of a ketogenic diet on clinical outcomes and immunological markers in myasthenia gravis: A randomized pilot study [0.03%]
一项关于生酮饮食对重症肌无力临床疗效和免疫学标志物影响的随机初步研究
Benjamin Makus,Daniel Schulze,Sophie Lehnerer et al.
Benjamin Makus et al.
Objective: Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating weakness and disabling fatigue. This pilot study assessed the feasibility and explored potential clinical and immunolo...
Randomized Controlled Trial
Journal of autoimmunity. 2026 May:160:103562. DOI:10.1016/j.jaut.2026.103562 2026
The clinical, functional and imaging landscape of lung involvement in Sjögren Disease: a potential link between interstitial lung disease and small airways dysfunction [0.03%]
原发性舍格伦综合征肺受累的临床、功能和影像学特征:间质性肺疾病与小气道功能障碍之间的潜在联系
Andreas V Goules,Panagiotis K Panagopoulos,Loukas Chatzis et al.
Andreas V Goules et al.
Background: Interstitial lung disease (ILD) and small airways disease (SAD) are prominent pulmonary manifestations of Sjögren disease (SjD) but their association and real prevalence are still elusive. Our purpose was to ...
Free water in the hippocampal cingulum as a Radiomic biomarker for Identifying inflammatory neuropsychiatric Lupus: A cross-sectional case-control study [0.03%]
基于放射组学的海马环状束中自由水作为鉴别炎症性神经精神狼疮的生物标志物:横断面病例对照研究
Zhenxing Li,Huanhuan Li,Bailing Tian et al.
Zhenxing Li et al.
Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious manifestation of systemic lupus erythematosus (SLE), yet its neuroimaging diagnosis remains challenging. This study aims to explore the value of ...
Glycoursodeoxycholic acid regulates peritoneal monocytic myeloid-derived suppressor cells to alleviate systemic inflammation in decompensated cirrhosis [0.03%]
甘糖胆酸通过调节腹腔单核细胞来源的肌苷抑制细胞来缓解失代偿期肝硬化患者的全身炎症反应
Rui Wang,Binghong Wang,Bo Li et al.
Rui Wang et al.
Objectives: Decompensated cirrhosis represents the end-stage of chronic liver diseases and is characterized by cirrhosis-associated immune dysfunction (CAID). Our goal was to characterize the peritoneal immune landscape, ...
Takayasu arteritis phenotypes and outcomes: A data-driven cluster analysis from a large international cohort [0.03%]
塔卡克斯动脉炎的临床亚型和转归特征:来自国际大样本队列的数据驱动聚类分析
Matheus Vieira,Elie Ghayad,Florence A Aeschlimann et al.
Matheus Vieira et al.
Background: Takayasu arteritis is a large-vessel vasculitis with polymorphic clinical presentation and outcomes. In this large multi-ethnic Takayasu cohort, we aimed to determine how factors present at diagnosis cluster t...
Mapping the neuropathic-sensory-affective pain axis in Sjögren's disease toward neuropsychological phenotyping [0.03%]
自身免疫性干燥综合症的神经病理-感觉-情感共病轴的脑影像学研究及神经心理表型预测建模初探
Saviana Gandolfo,Flavia Riccio,Rosaria Irace et al.
Saviana Gandolfo et al.
Background: Pain is one of the most disabling manifestations of Sjögren's disease (SjD). Whether neuropathic descriptors, sensory abnormalities and depressive symptoms represent distinct or integrated dimensions of the S...
Autoimmune modulation of immune-endocrine-metabolic regulation of ovarian reserve: A cohort study of 803 women [0.03%]
自身免疫调节卵巢储备的免疫-内分泌-代谢机制:一项纳入803名女性的研究
Ae Ra Han,Monira Alzahrani,Thanh V Luu et al.
Ae Ra Han et al.
Anti-Müllerian hormone (AMH) is an early functional marker of diminished ovarian reserve and premature ovarian insufficiency (POI), yet the immunologic context underlying AMH variation remains incompletely defined. Because ovarian autoimmu...