Shuliang Guo,Yingwei Liu,Angela Ryan et al.
Shuliang Guo et al.
Establishment and maintenance of specialized CMs in the heart is critical for the proper cardiac structure and function. Conversely, loss or gain of their identities is associated with various heart diseases such as cardiac arrythmia and ca...
Yin Wang,Di Ren,Randy Kang et al.
Yin Wang et al.
The emergence of single nucleus multiome sequencing (snMultiome-seq) technology has greatly advanced our understanding of various biological processes. However, existing experimental protocols fail to isolate high-quality nuclei from cryopr...
Corrigendum to "MMP19 in vascular smooth muscle cells protects against thoracic aortic aneurysm and dissection via the MMP19/Aggrecan/Wnt/β-catenin axis"[J Mol Cell Cardiol. 202 (2025) 35-49] [0.03%]
“MMP19通过MMP19/aggrecan/Wnt/β-catenin轴保护血管平滑肌细胞免受胸主动脉瘤和夹层的损害”[J Mol Cell Cardiol. 202 (2025) 35-49]的勘误表
Baihui Ma,Qingyi Zeng,Fangfang Yang et al.
Baihui Ma et al.
Cytoplasmic RBM20 gain-of-function induces atrial arrhythmogenicity independent of splicing defects in a novel murine model [0.03%]
胞浆RBM20功能过度活化通过独立于剪接缺陷的机制诱导心房颤动【小鼠模型】
Brijesh Sathian,Javed Iqbal,Syed Muhammad Ali
Brijesh Sathian
Martin E Young,Vanya Khanna,Mallory Metcalfe et al.
Martin E Young et al.
This review tracks the discovery of circadian biology in cardiovascular science, starting with early clinical observations of daily changes in heart rate, blood pressure, and cardiovascular events. These patterns suggested that time of day ...
Long-term exercise training is associated with unique cardiac troponin I phosphorylation pattern and benign myocardial hypertrophy in the right ventricle in an experimental model of exercise-induced myocardial remodelling [0.03%]
长期运动训练与运动诱导的心肌重塑动物模型中独特的肌浆钙结合蛋白C肌球蛋白结合位点磷酸化模式和良性右心室肥厚有关
Attila Oláh,Beáta Bódi,Bálint András Barta et al.
Attila Oláh et al.
Background: Research projects have focused on exercise-induced alterations of the right ventricle (RV) of the heart, because the exercise-associated disproportionate load on the RV might lead to pathological consequences,...
Paracrine IGFBP3 spatially coordinates IGF signaling to induce myocardial regeneration in mice [0.03%]
旁分泌IGFBP3调控IGF信号诱导小鼠心肌再生
Shah R Ali,Ngoc Uyen Nhi Nguyen,Waleed Elhelaly et al.
Shah R Ali et al.
We hypothesized that the microenvironment of the regenerating neonatal mouse heart contains pro-mitotic factors. To identify non-cell-autonomous effectors of cardiomyocyte mitosis, we analyzed a transcriptomic screen of regenerating and non...
Cell type specificity of hippo-YAP signaling in cardiac development and disease [0.03%]
Hippo-YAP信号在心脏发育和疾病中的细胞类型特异性
Jin Guan,Dominic P Del Re
Jin Guan
The Hippo-YAP pathway is an evolutionarily conserved signaling module that regulates cell survival, proliferation, and differentiation to control organ size. Recent work has demonstrated critical roles for Hippo-YAP signaling in cardiac dev...
Genetical TRPV4 deletion-associated gut microbiota alleviates cardiac dysfunction in mice with diabetic cardiomyopathy [0.03%]
遗传学TRPV4缺失相关肠道微生物群可缓解糖尿病心肌病小鼠的心脏功能障碍
Yanyan Zhou,Teng Yang,Suyang Zheng et al.
Yanyan Zhou et al.
Diabetic cardiomyopathy (DCM) is a serious complication associated with diabetes that characterized by the cardiac dysfunction and myocardial fibrosis. Recent studies emphasize the significance of the gut-heart axis in the development of DC...