A semantics for Boolean networks consistent with regulatory threshold constraints [0.03%]
与调节阈值约束一致的布尔网络语义学
Philippe Dague
Philippe Dague
Modeling biological systems with Boolean networks (BNs) is a well-established approach that enables reasoning about the qualitative dynamics of such systems, such as gene and signaling networks. Several semantics for BNs, i.e., scheduling o...
Modeling tumor progression in heterogeneous microenvironments: A cellular automata approach [0.03%]
异质微环境中基于元胞自动机的肿瘤细胞体模研究肿瘤的进化过程
Yue Deng,Mingjing Li,Jinzhi Lei
Yue Deng
Understanding how microenvironmental heterogeneity influences tumor progression is essential for advancing both cancer biology and therapeutic strategies. In this study, we develop a cellular automata (CA) model to simulate tumor growth und...
Simple cellular Potts model of scratch assays on healthy and keloid fibroblasts driven by contact inhibition of locomotion [0.03%]
由运动受抑制的细胞接触驱动的健康细胞和瘢痕疙瘩成纤维细胞刮痕测定的简单元胞波兹模型
Stéphane Urcun,Yasmin El Mahi,Raluca Eftimie et al.
Stéphane Urcun et al.
In this study, we propose and validate a simple agent-based model to study cell-cell interactions and cell migration during in vitro scratch assays in the context of cutaneous fibrosis (keloid). For model parametrization, we collect data fr...
An individual-based simulation framework exploring the ecology and mechanistic underpinnings of larval crowding in laboratory populations of Drosophila [0.03%]
探索果蝇实验室种群幼虫聚集的生态学和机制基础的个体基于模拟框架
Srikant Venkitachalam,Amitabh Joshi
Srikant Venkitachalam
The study of larval competition in laboratory populations of Drosophila, implemented via the crowding of larval cultures, has contributed greatly to the understanding of the ecology of competition, the evolution of larval competitive abilit...
On the dynamics of antigen receptors on the B-cell membrane through a two-dimensional stochastic process [0.03%]
二维随机过程中的B细胞膜抗原受体动力学研究
Verdiana Mustaro,Vincenzo Casolaro,Antonio Di
Verdiana Mustaro
B cells are important components of the adaptive immune system, responsible for antibody production and working as antigen-presenting cells. B cells display protein receptors on their membrane, which bind with foreign antigens and process t...
Social mixing and time use throughout the year: Potential changes in disease transmission and age distribution of cases [0.03%]
全年社会交往和时间利用情况：疾病传播及病例年龄分布变化的潜在影响
Edwin Van Leeuwen,Frank G Sandmann,Rosalind M Eggo et al.
Edwin Van Leeuwen et al.
Susceptibility in children is a key driver of heterogeneity in the transmission of different respiratory viruses. For example, SARS-CoV-2 is associated with low susceptibility in children, while for the influenza and respiratory syncytial v...
Characterisation of conserved and reacting moieties in chemical reaction networks [0.03%]
化学反应网络中保守流和反应流的特征分析
Hadjar Rahou,Hulda S Haraldsdóttir,Filippo Martinelli et al.
Hadjar Rahou et al.
A detailed understanding of biochemical networks at the molecular level is essential for studying complex cellular processes. In this paper, we provide a structural description of biochemical networks by considering individual atoms and che...
Branch length statistics in phylogenetic trees under constant-rate birth-death dynamics [0.03%]
恒定速率的物种分化灭绝模型下系统树分支长度的统计性质研究
Tobias Dieselhorst,Johannes Berg
Tobias Dieselhorst
Phylogenetic trees represent the evolutionary relationships between extant lineages, where extinct or non-sampled lineages are omitted. Extending the work of Stadler and collaborators, this paper focuses on the branch lengths in phylogeneti...
Habitat fragmentation promotes spatial scale separation under resource competition [0.03%]
生境破碎化在资源竞争中促进空间尺度分离
James Austin Orgeron,Malbor Asllani
James Austin Orgeron
Habitat fragmentation, often driven by human activities, alters ecological landscapes by disrupting connectivity and reshaping species interactions. In such fragmented environments, habitats can be modeled as networks, where individuals dis...