Cytokeratin Detection in Lymphoid Tumor Cell Lines: Implications for Flow Cytometry and Molecular Analyses [0.03%]
淋巴瘤细胞系角蛋白检测：流式细胞术和分子分析的含义
Natsuko Mizutani,Shiori Takeuchi,Akemi Koyanagi et al.
Natsuko Mizutani et al.
Cytokeratins are widely used as epithelial markers in diagnostic pathology and flow cytometry, and malignant lymphomas are generally considered cytokeratin-negative except for undifferentiated large cell lymphomas. During antibody screening...
Nethma Hewa Waduge,Junhua Xiao,Gregory M Davis
Nethma Hewa Waduge
The BRCA1-BARD1 complex is a vital protein that promotes homologous recombination, acting through its E3 ubiquitin ligase activity. Although ubiquitination remains its only confirmed enzymatic function, emerging evidence suggests that the c...
Mitochondria-Associated Endoplasmic Reticulum Membranes in Cancer: Hubs for Tumor Progression and Therapeutic Vulnerabilities [0.03%]
线粒体相关内质网膜在癌症中的作用：肿瘤进展和治疗脆弱性的中心位置
Linlin Yan,Shaoqing Liu,Kai Wu et al.
Linlin Yan et al.
Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic contact sites between the endoplasmic reticulum (ER) and mitochondria that coordinate multiple cellular processes such as calcium signaling, lipid trafficking, and r...
Small Extracellular Vesicle-TLN1 Modulates Gastric Cancer Cells and Remodels Lymphatic Endothelial Cells Through AKT Activation to Potentiate Lymphatic Metastasis [0.03%]
小型细胞外囊泡-TLN1通过激活AKT来调节胃癌细胞和重塑淋巴内皮细胞，以增强淋巴转移
Yuanyuan Li,Jing Wen,Xiaoli Cao et al.
Yuanyuan Li et al.
Lymph node metastasis is a pivotal determinant of poor prognosis of gastric cancer, but the molecular orchestrators of lymphatic dissemination remain poorly characterized. Recent research highlights the pivotal role of small extracellular v...
Adipose-Derived Stem Cells Differentiate Into Insulin-Producing Cells in 2D Culture With Photobiomodulation: A Comparative Analysis of Wavelength and Fluence Parameters [0.03%]
光生物调节使脂肪来源干细胞在二维培养中分化为胰岛素产生细胞：波长和通量参数的比较分析
O Daramola,H Abrahamse,A Crous
O Daramola
Diabetes mellitus is a chronic metabolic disorder characterized by the loss or dysfunction of insulin-producing beta (β) cells. Adipose-derived stem cells (ADSCs) represent a promising source for generating functional insulin-producing β ...
Comparative Study
Cell biology international. 2026 Jul;50(7):e70182. DOI:10.1002/cbin.70182 2026
Impaired Neurosphere Formation as a Functional Readout of Aberrant EGFR Signaling Kinetics in Olfactory Neural Progenitors From Patients With Schizophrenia [0.03%]
精神分裂症患者嗅球神经祖细胞异常EGFR信号动力学的功能读出：神经球形成受损
Tommaso Toffanin,Mario Angelo Pagano,Carlo Idotta et al.
Tommaso Toffanin et al.
The Epidermal Growth Factor Receptor (EGFR) is a key regulator of neurodevelopment, controlling the proliferation, differentiation, and self-renewal of neural stem and progenitor cells. Dysregulated EGFR signaling has been implicated in sch...
Mechanobiology-Driven Metabolic Reprogramming: Integrative Roles of YAP/TAZ Signaling and Extracellular Matrix Dynamics [0.03%]
力学调控的代谢重塑：YAP/TAZ信号和细胞外基质整合型作用
Arul Narayanasamy,Panimalar Abirami Karuppusamy,Roselin Gnanarajan et al.
Arul Narayanasamy et al.
Mechanobiology has emerged as a critical regulator of cellular metabolism, linking physical forces to transcriptional, metabolic, and epigenetic adaptations across multiple organ systems. However, the mechanisms by which extracellular matri...
NPC2 Regulates Glioblastoma Cholesterol Metabolism and Malignant Behavior via GPX4-Linked Ferroptosis [0.03%]
NPC2通过GPX4连接的铁死亡调节胶质母细胞瘤胆固醇代谢和恶性行为
Wei Jiang,Wei Wang,Junping Wang et al.
Wei Jiang et al.
Glioblastoma (GBM) is a highly aggressive intracranial malignancy originating from neuroepithelial glial progenitors. The prominent intra- and intertumoral heterogeneity of GBM is a major driver of therapeutic resistance and frequent tumor ...
Icariin as a Modulator of Cancer Cell Biology: Integrated Control of Proliferation, Cell Death Programs, Metastasis Signaling, and Delivery Challenges [0.03%]
淫羊藿黄素在癌症细胞生物学中的作用及其面临的挑战：整合调控增殖、细胞死亡程序、转移信号及递送问题
Putri Cahaya Situmorang,Cheryl Grace Pratiwi Rumahorbo,Alexander Patera Nugraha et al.
Putri Cahaya Situmorang et al.
Icariin, a prenylated flavonoid derived from plants of the Epimedium genus, has attracted increasing attention due to its broad spectrum of pharmacological activities, particularly its anticancer potential. Accumulating evidence indicates t...
Temporal Lysophosphatidic Acid Supplementation Enhances Megakaryocyte Differentiation and Platelet Production From Human Hematopoietic Progenitors [0.03%]
temporal lysophosphatidic acid 补充可增强人造血祖细胞巨核细胞的分化和血小板生成
Nittaya Jiamvoraphong,Chanchao Lorthongpanich,Praphasri Septham et al.
Nittaya Jiamvoraphong et al.
Platelet shortages and limited storage stability restrict global platelet transfusion capacity, highlighting the need for efficient in vitro platelet production systems. This study establishes a simple, non-genetic and cost-effective system...