Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound [0.03%]
透明质酸作为纤维蛋白膜急性伤口护理成分的优点
T V Anilkumar,Jaseer Muhamed,Anumol Jose et al.
T V Anilkumar et al.
Skin injury is followed by accumulation of a fibrin based provisional matrix which normally drives the process of wound repair. Exogenous fibrin with extra cellular matrix (ECM) components can also favor the wound healing process. In a prel...
Virus inactivation in albumin by a combination of alkali conditions and high temperature [0.03%]
碱性条件和高温结合灭活血清白蛋白中的病毒
Peter L Roberts,John More,Jackie Rott et al.
Peter L Roberts et al.
Non-enveloped viruses such as HAV and B19 are of potential concern in plasma products. In the case of albumin, pasteurisation at 60 °C for 10 h is generally used for virus inactivation. However this procedure is only partially effective ag...
Cloning and characterization of engA, a GTP-binding protein from Mycobacterium tuberculosis H(37)Rv [0.03%]
结核分枝杆菌engA基因的克隆与鉴定
Laxman S Meena,Rajni
Laxman S Meena
Guanine nucleotides are key signaling molecules and many members of the G-protein family bind and hydrolyze nucleotides, particularly GTP, and regulate intracellular level of GTP and GDP. EngA is one of the members of these universally cons...
The consistency approach for quality control of vaccines - a strategy to improve quality control and implement 3Rs [0.03%]
一致性方法疫苗质量控制-改进质量和实施3R策略
Fabrizio De Mattia,Jean-Michel Chapsal,Johan Descamps et al.
Fabrizio De Mattia et al.
Current batch release testing of established vaccines emphasizes quality control of the final product and is often characterized by extensive use of animals. This report summarises the discussions of a joint ECVAM/EPAA workshop on the appli...
Local tolerance and stability up to 24 months of a new 20% proline-stabilized polyclonal immunoglobulin for subcutaneous administration [0.03%]
一种新型用于皮下注射的含20%脯氨酸稳定的多克隆免疫球蛋白长达24个月的地方性和稳定性良好
Werner Maeder,Patricia Lieby,Andrea Sebald et al.
Werner Maeder et al.
Subcutaneous administration of human IgG is an alternative to intravenous replacement therapy that is associated with more stable serum IgG levels and fewer systemic adverse events. Highly concentrated IgG solutions are most convenient to m...
C1q aggregate binding for the determination of anti-complementary activity of immunoglobulin products [0.03%]
补体结合试验测定免疫球蛋白制品抗 complement 活性
Thanae Georgakopoulos,Owen C Tatford,Vladimir Gurevich et al.
Thanae Georgakopoulos et al.
Aggregates in human immunoglobulin (Ig) products can develop due to employed manufacturing, formulation and storage conditions and can cause adverse reactions in patients. The test for anti-complementary activity (ACA) recommended by the Eu...
A chemically defined production process for highly attenuated poxviruses [0.03%]
一种用于高度减毒痘病毒的化学明确生产过程
Ingo Jordan,Stefan Northoff,Michael Thiele et al.
Ingo Jordan et al.
Highly attenuated poxviruses are promising vectors for protective and therapeutic vaccines. These vectors do not replicate in human cells and can therefore be safely given even to immunocompromised recipients. They can accommodate very larg...
The role of non-human primates in the neurological safety of live viral vaccines (review) [0.03%]
非人灵长类在活病毒疫苗神经安全性评价中的作用（综述）
Inessa Levenbook
Inessa Levenbook
This review covers comprehensive data accumulated during the long history of using monkeys in the determination of neurovirulence activity and safety of live poliomyelitis, flaviviral, smallpox and mumps vaccines, as well as newly developed...
Contamination of infectious RD-114 virus in vaccines produced using non-feline cell lines [0.03%]
用非猫科细胞系生产的疫苗中感染性RD-114病毒污染状况的调查研究报告
Rokusuke Yoshikawa,Eiji Sato,Takayuki Miyazawa
Rokusuke Yoshikawa
All domestic cats have a replication-competent endogenous retrovirus, termed RD-114 virus, in their genome and several feline cell lines produce RD-114 viruses. Recently, we found that a portion of live attenuated feline and canine vaccines...
Effect of storage conditions on the stability of recombinant human MCP-1/CCL2 [0.03%]
储存条件对重组人MCP-1/CCL2稳定性的影响
Krisada Leemasawatdigul,Heather Gappa-Fahlenkamp
Krisada Leemasawatdigul
Monocyte chemoattractant protein-1 (MCP-1) is commercially available in a form of recombinant protein. This makes it more convenient to study the functions of MCP-1 and its involvement in many cell functions. However, when using MCP-1 in ex...