Development of a novel competitive ELISA method for Typhoid Vi Polysaccharide Quantitation [0.03%]
一种新型的竞争型酶联免疫吸附法用于伤寒Vi多糖定量检测的发展研究
Ashwani Kumar Mandyal,Rajasekaran Angannan,Balananda Dhurjati Kumar Putcha et al.
Ashwani Kumar Mandyal et al.
Licensed typhoid vaccines contain Vi polysaccharide (ViPS), a capsular antigen of Salmonella. Typhi (S.typhi), either unconjugated or conjugated to carrier proteins like tetanus toxoid (TT), diphtheria toxoid (DT), and Cross-reactive materi...
Report of the international conference on animal testing replacement for vaccines: A one health view on global outlook and future strategy [0.03%]
关于疫苗替代动物实验的国际会议报告——从全球视角和未来战略看“同一健康”政策的影响
Laura Viviani,Evelin Balbino,Meenu Batolar et al.
Laura Viviani et al.
The transition toward non-animal methods for vaccine quality control has accelerated in recent years, driven by scientific advances and evolving regulatory expectations. To assess the current status of replacing animal-based methods, intern...
Pyrogen testing 2.0: Ethical, evolving and eco-friendly - Implementing safe, rapid, state-of-the-art and sustainable non-animal approaches worldwide. A meeting report [0.03%]
免动物药理学检查2.0：伦理的、发展的和环保的——在全球实施安全、快速、尖端且可持续的非动物方法的一次会议报告
Charton E,Hornik A,Schütte K et al.
Charton E et al.
Practical screening and monitoring tools for out-of-specification risk in biological products under finite sample sizes [0.03%]
有限样本量下生物制品偏差风险筛查和监测工具的研究
Michikazu Tanio,Isao Hamaguchi,Takuo Mizukami
Michikazu Tanio
Evaluating the risk of out-of-specification (OOS) occurrence before it happens is essential to prevent delays or interruptions in the supply of biological products. This study proposes a practical and quantitative evaluation approach using ...
Neutralizing antibodies are not detected against endogenous bacteriophages in their respective host [0.03%]
在相应宿主中未检测到针对内源性噬菌体的中和抗体
Sonam Rastogi,Alka Shukla,Mayank Gangwar et al.
Sonam Rastogi et al.
Introduction: Bacteriophages are increasingly recognized as vital modulators of the human microbiome and promising candidates for alternative antimicrobial therapies. Critics raise concerns about immune neutralization wit...
Comment on "Preparation of poloxamer-based CPV virus-like particle vaccine and its immunological evaluation in mice" [0.03%]
关于“基于聚氧乙烯嵌段共聚物的细小病毒疫苗制备及其免疫效果评价”的评论
Tanmay Ailani,Reenoo Jauhari,Anjna Rani et al.
Tanmay Ailani et al.
Conformational dynamics of pneumococcal polysaccharide conjugates drive UV-vis quantification errors and a strategy to enable UV-vis spectrophotometer quantification [0.03%]
肺炎链球菌多糖结合疫苗的构象动力学导致紫外可见光定量误差及紫外可见分光光度计定量策略
Minghua Zheng,Huanhuan Cao,Yuetong Li et al.
Minghua Zheng et al.
Accurate quantification of polysaccharide content is indispensable for the development and quality control of glycoconjugate vaccines. Conventional methods are often laborious, require large sample volumes, or are susceptible to interferenc...
Refining the regulatory and ethics context of controlled human infection models - a stakeholder meeting report [0.03%]
调控人类感染模型的监管和伦理环境的研究进展——利益相关者会议报告
Victor Cnossen,Annefleur Hensen,Laura Pattacini et al.
Victor Cnossen et al.
Longevity of humoral response in recipients of rabies pre-exposure prophylactic vaccination with Abhayrab® [0.03%]
阿拜拉布疫苗 rab 预防接种者的免疫持续性研究
Bhaskar Ganguly,Rajashakar Bellamcapu,Madhavi Charepalli et al.
Bhaskar Ganguly et al.
The results of a retrospective analysis of data on rabies virus neutralizing antibody titers of occupationally at-risk individuals receiving vaccination with Abhayrab®, a Vero cell culture-derived inactivated rabies vaccine, are communicat...
Collaborative studies to establish WHO International Reference Reagents for diphtheria and tetanus antitoxin for use in the flocculation test [0.03%]
合作研究建立用于絮凝试验的白喉和破伤风抗毒素WHO国际标准
Shalini Rajagopal,Rob Tierney,Jason Hockley et al.
Shalini Rajagopal et al.
Here we report the results of the collaborative studies to establish a WHO International Reference Reagent (IRR) for Diphtheria Antitoxin for use in Flocculation Test (coded 23/102) and a WHO IRR for Tetanus Antitoxin for use in Flocculatio...