Paul J Branham,Hans C Cooper,Yulanda M Williamson et al.
Paul J Branham et al.
This manuscript describes the use of an analytical assay that combines transfection of mammalian cells and isotope dilution mass spectrometry (IDMS) for accurate quantification of antigen expression. Expired mRNA COVID-19 vaccine material w...
Rajesh Gupta,Griffiths Elwyn,Girish Vyas et al.
Rajesh Gupta et al.
Expression and purification of Hepatitis B virus core antigen using Escherichia coli and its utilization for the diagnosis of Hepatitis B virus infections [0.03%]
利用大肠杆菌表达、纯化乙型肝炎病毒核心抗原及其应用研究
Mohammed El-Mowafy,Mohamed El-Mesery,Mahmoud A F Khalil et al.
Mohammed El-Mowafy et al.
Hepatitis B virus (HBV) is responsible for most of the viral hepatitis worldwide. HBV is a partially double stranded DNA virus that is composed of four main open reading frames (ORFs) encoding its important antigens, namely hepatitis B surf...
Evaluating the sensitivity of newborn rats and newborn hamsters to oncogenic DNA [0.03%]
评价新生大鼠和新生仓鼠对致癌DNA的敏感性
Li Sheng-Fowler,Wei Tu,Kathryn Phy et al.
Li Sheng-Fowler et al.
To evaluate the risk of residual cellular DNA in vaccines manufactured in tumorigenic cell lines, we have been establishing in vivo assays to quantify the oncogenic activity of DNA. We had generated three oncogene-expression plasmids: pMSV-...
Enabling the evaluation of COVID-19 vaccines with correlates of protection [0.03%]
启用COVID-19疫苗保护指标评估
Arnaud Marchant,Pierre Van Damme,Stanley Plotkin et al.
Arnaud Marchant et al.
In February 2023, a meeting about correlates of protection (CoPs) against COVID-19 was organized by the International Alliance for Biological Standardization, the European Plotkin Institute for Vaccinology, and Vaccinopolis. The meeting aim...
A rapid and simple sterility test method based on solid culture medium containing blood [0.03%]
一种基于含血液固体培养基的快速简便的无菌检测方法
Neetu Raghav,Seema Parveen,Simleen Kaur et al.
Neetu Raghav et al.
Current sterility test performed for most biological products takes 14 days. We evaluated solid medium, containing 5% blood for use in the membrane filtration (MF) and direct inoculation (DI) sterility test. Representative microorganisms pr...
Nano-emulsion encapsulation for the efficient delivery of bacteriophage therapeutics [0.03%]
纳米乳液封装技术有效输送噬菌体疗法药物的新方法
Loushambam Samananda Singh
Loushambam Samananda Singh
Antibiotic resistance has become the major concern for global public health. Phage therapy is being considered as an alternative for antibiotics to treat the multidrug resistant bacterial infections. Bacteriophage therapeutic developments h...
Development and evaluation of recombinant gD protein based ELISA for sero-surveillance of BoHV-1 in India [0.03%]
在印度开发和评估基于重组gD蛋白的伪狂犬病病毒BoHV-1血清学调查ELISA方法及其评价
Sushmita Nautiyal,Sukdeb Nandi,Kirtika Sharma et al.
Sushmita Nautiyal et al.
Bovine herpes virus-1 (BoHV-1) is responsible for production losses through decreased milk yields, abortions, infertility, and trade restrictions in the bovine population. The disease is endemic in many countries including India. As the vir...
Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities [0.03%]
基于国家控制实验室和国家监管机构调查问卷的WHO生物制品批签发检验指南中3R措施整合方案回复
Elliot Lilley,Martijn Bruysters,Pradip Das et al.
Elliot Lilley et al.
The UK National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) is reviewing World Health Organization (WHO) manuals, guidelines and recommendations for vaccines and biotherapeutics to identify the exten...
Corrigendum to "Comparison of Astra Zeneca and sinopharm vaccines as boosters in protection against COVID-19 infection" [Biologicals 82 (2023) 101668] [0.03%]
阿斯利康和国药疫苗作为加强针在预防COVID-19感染方面的保护效果比较的勘误说明（发表于生物制品期刊第82卷(2023)页码101668）
Arash Letafati,Nooshin Eyvazzadeh,Amirhossein Gharehkhani et al.
Arash Letafati et al.