Ulinastatin-mediated protection against zymosan-induced multiple organ dysfunction in rats [0.03%]
乌司他丁通过减轻幽门螺杆菌诱导的胃粘膜损伤保护小鼠胃肠功能障碍模型多器官功能受损的作用研究
Qiuping Yang,Xingang Liu,Min Liu et al.
Qiuping Yang et al.
The purpose of this study was to evaluate the potential organ-protective activity of ulinastatin (a urinary trypsin inhibitor) and to investigate the underlying mechanism(s) in a rat model of multiple organ dysfunction syndrome (MODS). When...
Isoforms of p63 in corneal stem cells cultured on human amniotic membrane [0.03%]
人羊膜上培养的角膜干细胞中p63异构体的表达
Sasirekha Krishnan,Balasubramanian Sudha,Subramanian Krishnakumar
Sasirekha Krishnan
The p63 gene supports stem cell proliferation and regulation in epithelial cells. In this study, corneal epithelial cells were cultured on human amniotic membrane (HAM) and investigated for p63 and its isoform genes. Human limbal biopsies o...
Effects of anti-TNF therapy on glucose metabolism in patients with ankylosing spondylitis, psoriatic arthritis or juvenile idiopathic arthritis [0.03%]
抗肿瘤坏死因子治疗对强直性脊柱炎、银屑病关节炎或幼年特发性关节炎患者的糖代谢的影响
Bárbara Santos Pires da Silva,Eloísa Bonfá,Júlio César Bertacini de Moraes et al.
Bárbara Santos Pires da Silva et al.
The objective of this study was to evaluate the influence of anti-tumor necrosis factor (anti-TNF) in juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS) or psoriatic arthritis (PsA). Sixty-two patients were investigated: 7 JIA...
Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom [0.03%]
玻帕斯蛇蛇毒血清效价估计方法的研究及中和效力测定法的分析性质探讨
Gabriela Solano,Alvaro Segura,María Herrera et al.
Gabriela Solano et al.
The lethality neutralization assay performed in mice is the standard recommended by the World Health Organization to estimate antivenom potency. The interpretation of its results without considering its analytical capacity may lead to erron...
Comparison of the physicochemical properties of a biosimilar filgrastim with those of reference filgrastim [0.03%]
一种生物仿制粒细胞集落刺激因子与原研药理化特性比对研究
A Skrlin,I Radic,M Vuletic et al.
A Skrlin et al.
Recombinant human granulocyte-colony stimulating factor (filgrastim) is a therapeutic protein used primarily to reduce incidence and duration of severe neutropenia and its associated, and serious, complications. We have developed a biosimil...
Validation of the safety of MDCK cells as a substrate for the production of a cell-derived influenza vaccine [0.03%]
用于生产细胞流感疫苗的MDCK细胞安全性的验证研究
David Onions,William Egan,Ruth Jarrett et al.
David Onions et al.
Cell culture-based production methods may assist in meeting increasing demand for seasonal influenza vaccines and developing production flexibility required for addressing influenza pandemics. MDCK-33016PF cells are used in propagation of a...
Replicating viral vectors as HIV vaccines: summary report from the IAVI-sponsored satellite symposium at the AIDS vaccine 2009 conference [0.03%]
艾滋病疫苗会议上的国际艾滋病疫苗倡议组织卫星研讨会的总结报告：作为HIV疫苗的复制病毒载体
J L Excler,C L Parks,J Ackland et al.
J L Excler et al.
In October 2009, The International AIDS Vaccine Initiative (IAVI) convened a satellite symposium entitled 'Replicating Viral Vectors for use in AIDS Vaccines' at the AIDS Vaccine 2009 Conference in Paris. The purpose of the symposium was to...
Betty Dodet,Wim Hesselink,Carmen Jungbäck et al.
Betty Dodet et al.
Paul-Pierre Pastoret
Paul-Pierre Pastoret
Vaccination is one of the most important public health accomplishments. However, since vaccine preparation involves the use of materials of biological origin, vaccines are subject to contamination by micro-organisms. In fact, vaccine contam...
Heparin identification test and purity test for OSCS in heparin sodium and heparin calcium by weak anion-exchange high-performance liquid chromatography [0.03%]
采用弱阳离子交换高效液相色谱法测定肝素钠和肝素钙中的OSCS的含量及其纯度
Noritaka Hashii,Nana Kawasaki,Satsuki Itoh et al.
Noritaka Hashii et al.
Heparin sodium and heparin calcium, which are widely used as anti-coagulants, are known to potentially contain the natural impurity dermatan sulfate (DS). Recently serious adverse events occurred in patients receiving heparin sodium in the ...