Botulinum neurotoxins: A distinct subclass of SNARE-Cleaving endopeptidases [0.03%]
肉毒神经毒素：独特的SNARE蛋白裂解内肽酶亚类
Sabine Pellett
Sabine Pellett
Botulinum neurotoxins (BoNTs) are bacterial protein toxins that cause the severe and potentially fatal neuro-paralytic disease botulism in humans and vertebrate animals. Together with tetanus toxin (TeNT), BoNTs comprise the large family of...
Protective role of Probiatop® in mitigating 5-fluorouracil-induced intestinal mucositis in mice [0.03%]
ProbioTOP对小鼠5-氟尿嘧啶致肠黏膜炎的保护作用研究
Fernanda C Souza,Bruno Gallotti,Lara L Campos et al.
Fernanda C Souza et al.
Aims: Mucositis is an inflammatory condition affecting the gastrointestinal mucosa and is a common adverse effect of chemotherapy, particularly following treatment with 5-fluorouracil (5-FU). Currently, therapeutic option...
Vertebrate host or tick vector? Who is to blame for Borrelia lusitaniae population structure? [0.03%]
宿主或媒介？谁才是产生波氏莱姆病螺旋体种群结构的罪魁祸首？
Ana Cláudia Norte,Miguel A Carretero,Luís P da Silva et al.
Ana Cláudia Norte et al.
Objective: Borrelia lusitaniae is a lizard-associated spirochaete which shows highly genetically structured populations in western Europe. Our objective was to assess whether selective forces acting on the Ixodes tick vec...
Advances in Clostridioides difficile research: Insights from the 8th International C. difficile symposium (ICDS 2024) [0.03%]
第八届国际艰难梭菌研讨会（ICDS 2024）的艰难梭菌研究进展：新见解
Sandra Janezic,Marcela Krutova,Gayatri Vedantam
Sandra Janezic
The role of Fusobacterium nucleatum in the pathogenesis of endometriosis: A microbial and microenvironmental perspective [0.03%]
Fusobacterium nucleatum在子宫内膜异位症发病机制中的作用：微生物和微环境视角
Nabiha B Remmani,Zineb S Harous,Rand Q Alzaidy et al.
Nabiha B Remmani et al.
Endometriosis is a chronic, inflammatory gynecological condition characterized by the ectopic growth of endometrial-like tissue, with an unclear etiology and limited treatment efficacy. Recent studies implicate the oral and gut commensal ba...
In vitro susceptibility of bovine digital dermatitis treponemes to conventional and novel antimicrobial agents, and evidence of heavy metal resistance [0.03%]
牛 DIGITODONTIIS 螺旋体对常规和新型抗菌剂的体外敏感性以及重金属耐药性的证据
Amy Gillespie,Sam Haldenby,Roger Blowey et al.
Amy Gillespie et al.
Objectives: Bovine digital dermatitis (BDD) is a globally endemic, painful infectious foot disease of cattle; however, gaps in knowledge regarding treatment efficacy limit our ability to control it. Our objectives were to...
Marion Dutkiewicz,József Sóki,Etienne Ruppé
Marion Dutkiewicz
Anaerobic bacteria in the human intestinal microbiota play a pivotal role in antibiotic resistance, primarily through the production of β-lactamases. This narrative review explores the diversity of β-lactamases found in intestinal anaerob...
Francisco A Uzal,Mauricio A Navarro,Javier Asin et al.
Francisco A Uzal et al.
Clostridioides difficile affects humans, and several other animal species, such as horses, pigs, gerbils, guinea pigs, hamsters, and rabbits. This microorganism has also been isolated from the gastrointestinal tract of healthy individuals o...
External quality assessment in antimicrobial susceptibility testing (EUCAST disc diffusion methodology) of five anaerobic strains - performance of 35 laboratories in Germany and Austria, 2024 [0.03%]
2024年德国和奥地利35家实验室五种厌氧菌抗菌药物敏感性测试（EUCAST纸片扩散法）外部质量评估性能分析
Michael Buhl,Jette Jung,Catalina-Suzana Stingu et al.
Michael Buhl et al.
This study evaluated the performance of antimicrobial susceptibility testing (AST) for anaerobic bacteria among 35 clinical microbiology laboratories in Germany and Austria through an interlaboratory comparison (ILC) challenge. A panel of f...
Clostridioides difficile colonization of Twin Patients Recovering From Infant Botulism [0.03%]
双胞胎婴儿肉毒杆菌中毒恢复期的艰难梭菌定植
Jason R Barash,Susan P Sambol,Andrew M Skinner et al.
Jason R Barash et al.
Objectives: The prevalence of Clostridioides difficile co-colonization of 107 California patients with suspect infant botulism (IB) was studied over a two-year period. One set of twins with lab-confirmed IB and C. diffici...