Non-genomic actions of estrogens and their interaction with genomic actions in the brain [0.03%]
雌激素的非基因组作用及其与脑内基因组作用的相互作用
Nandini Vasudevan,Donald W Pfaff
Nandini Vasudevan
Ligands for the nuclear receptor superfamily have at least two mechanisms of action: (a) classical transcriptional regulation of target genes (genomic mechanisms); and (b) non-genomic actions, which are initiated at the cell membrane, which...
Joanna L Spencer,Elizabeth M Waters,Russell D Romeo et al.
Joanna L Spencer et al.
Estrogens have direct effects on the brain areas controlling cognition. One of the most studied of these regions is the dorsal hippocampal formation, which governs the formation of spatial and episodic memories. In laboratory animals, most ...
Corticosteroid hormones in the central stress response: quick-and-slow [0.03%]
中枢压力反应中的皮质类固醇激素：快速和慢速反应
E Ronald de Kloet,Henk Karst,Marian Joëls
E Ronald de Kloet
Recent evidence shows that corticosteroid hormones exert rapid non-genomic effects on neurons in the hypothalamus and the hippocampal CA1 region. The latter depend on classical mineralocorticoid receptors which are accessible from the outsi...
A genome-wide inventory of neurohormone GPCRs in the red flour beetle Tribolium castaneum [0.03%]
红粉虫Tribolium castaneum神经激素受体基因组的鉴定及分析
Frank Hauser,Giuseppe Cazzamali,Michael Williamson et al.
Frank Hauser et al.
Insect neurohormones (biogenic amines, neuropeptides, and protein hormones) and their G protein-coupled receptors (GPCRs) play a central role in the control of behavior, reproduction, development, feeding and many other physiological proces...
The effects of non-genomic glucocorticoid mechanisms on bodily functions and the central neural system. A critical evaluation of findings [0.03%]
非基因组糖皮质激素机制对机体功能及中枢神经系统的效应：成果评价
József Haller,Eva Mikics,Gábor B Makara
József Haller
Mounting evidence suggests that--beyond the well-known genomic effects--glucocorticoids affect cell function via non-genomic mechanisms. Such mechanisms operate in many major systems and organs including the cardiovascular, immune, endocrin...
Role of PACAP in the physiology and pathology of the sympathoadrenal system [0.03%]
PACAP在交感肾上腺系统生理和病理中的作用
Hafida Ghzili,Luca Grumolato,Erwan Thouënnon et al.
Hafida Ghzili et al.
Sympathetic neurons and chromaffin cells derive from common sympathoadrenal precursors which arise from the neural crest. Cells from this lineage migrate to their final destination and differentiate by acquiring a catecholaminergic phenotyp...
Estrogen receptors: their roles in regulation of vasopressin release for maintenance of fluid and electrolyte homeostasis [0.03%]
雌激素受体在抗利尿激素释放及维持体液电解质平衡中的作用研究进展
Celia D Sladek,Suwit J Somponpun
Celia D Sladek
Long standing interest in the impact of gonadal steroid hormones on fluid and electrolyte balance has led to a body of literature filled with conflicting reports about gender differences, the effects of gonadectomy, hormone replacement, and...
Rapid actions of androgens [0.03%]
雄激素的快速作用
Guido Michels,Uta C Hoppe
Guido Michels
The biological activity of androgens is thought to occur predominantly through binding to intracellular androgen-receptors, a member of the nuclear receptor family, that interact with specific nucleotide sequences to alter gene expression. ...
Paul J Davis,Jack L Leonard,Faith B Davis
Paul J Davis
The nongenomic actions of thyroid hormone require a plasma membrane receptor or nuclear receptors located in cytoplasm. The plasma membrane receptor is located on integrin alphaVbeta3 at the Arg-Gly-Asp recognition site important to the bin...
Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review [0.03%]
雌激素对女性认知特定方面的神经保护作用受脑老化调节：一篇批判性评论
Barbara B Sherwin,Jessica F Henry
Barbara B Sherwin
Although there is now a substantial literature on the putative neuroprotective effects of estrogen on cognitive functioning in postmenopausal women, it is replete with inconsistencies. The critical period hypothesis, posited several years a...