Neurosteroid replacement approaches for improving outcomes after compromised pregnancies and preterm birth [0.03%]
神经类固醇替代疗法改善受损妊娠和早产儿预后的研究进展
Jonathan J Hirst,Hannah K Palliser,Carlton Pavy et al.
Jonathan J Hirst et al.
The levels of the key neurosteroid of pregnancy, allopregnanolone, are very high in the fetal and maternal brain compared to after birth. These levels are maintained by the placenta which forms a placental connection to fetal brain developm...
The oxytocin system in patients with craniopharyngioma: A systematic review [0.03%]
颅咽管瘤患者的催产素系统：一项系统性综述
Amy Mann,Jennifer Kalitsi,Khushali Jani et al.
Amy Mann et al.
Craniopharyngioma is a benign tumour affecting the hypothalamic and pituitary regions, which are involved in the production and secretion of oxytocin. We conducted a systematic review to assess dysregulation of the oxytocin system in cranio...
Unraveling sex differences in maternal and paternal care impacts on social behaviors and neurobiological responses to early-life adversity [0.03%]
揭示父爱和母爱对早期生活逆境所引起的社会行为及神经生物学反应的性别差异的影响机制
Shakeera L Walker,Erica R Glasper
Shakeera L Walker
Early-life stress (ELS) affects the development of prosocial behaviors and social-cognitive function, often leading to structural brain changes and increased psychosocial disorders. Recent studies suggest that mother- and father-child relat...
Insulin-like growth factor-1 and cognitive health: Exploring cellular, preclinical, and clinical dimensions [0.03%]
胰岛素样生长因子-1与认知健康：探讨细胞、前临床和临床维度
Cellas A Hayes,Destiny Wilson,Miguel A De Leon et al.
Cellas A Hayes et al.
Age and insulin-like growth factor-1 (IGF-1) have an inverse association with cognitive decline and dementia. IGF-1 is known to have important pleiotropic functions beginning in neurodevelopment and extending into adulthood such as neurogen...
Progestagens and progesterone receptor modulation: Effects on the brain, mood, stress, and cognition in females [0.03%]
孕激素和孕酮受体调节对女性大脑、情绪、压力和认知的影响
Celine Bencker,Laura Gschwandtner,Sibel Nayman et al.
Celine Bencker et al.
Progesterone is a highly lipophilic gonadal hormone that can influence behavior and mental health through its receptors in the brain. Fluctuations in progesterone levels across critical periods of a females life are associated with increase...
Sivaniya Subramaniapillai,Liisa Am Galea,Gillian Einstein et al.
Sivaniya Subramaniapillai et al.
Research policies aiming to integrate sex and gender in scientific studies are receiving increased attention in academia. Incorporating these policies into health research is essential for improving targeted and equitable healthcare outcome...
Brain alteration of autoimmune thyroid disease: Neuropsychiatric impact, neuroimaging insights, and neurobiological implications [0.03%]
自身免疫性甲状腺疾病的大脑改变：神经精神影响、神经影像学见解和神经生物学意义
Qin Wei,Haiyang Zhang,Haixia Guan et al.
Qin Wei et al.
Autoimmune thyroid disease (AITD) is the most common organ-specific autoimmune disease, characterized by thyroid function disorder and autoimmune imbalance. Previous studies have demonstrated the decreased quality of life and neuropsychiatr...
Melatonin and brain barriers: The protection conferred by melatonin to the blood-brain barrier and blood-cerebrospinal fluid barrier [0.03%]
褪黑素与脑屏障系统：褪黑激素对血脑屏障和血脑脊液屏障的保护作用
Rafael Mineiro,Maria Rodrigues Cardoso,Ana Catarina Duarte et al.
Rafael Mineiro et al.
The blood-brain barrier and the blood-cerebrospinal fluid barrier separate the blood from brain tissue and cerebrospinal fluid. These brain barriers are important to maintain homeostasis and complex functions by protecting the brain from xe...
Attila Zsarnovszky,Daiana Alymbaeva,Gergely Jocsak et al.
Attila Zsarnovszky et al.
Neural regulation of the homeostasis depends on healthy synaptic function. Adaptation of synaptic functions to physiological needs manifests in various forms of synaptic plasticity (SP), regulated by the normal hormonal regulatory circuits....
Effect of 5-alpha reductase inhibitors in animal models of Parkinson's disease [0.03%]
雄激素受体拮抗剂防治帕金森病动物模型发病的效应研究
Mélanie Bourque,Marc Morissette,Amandine Isenbrandt et al.
Mélanie Bourque et al.
Parkinson's disease (PD) is characterized by motor symptoms due to loss of brain dopamine and non-motor symptoms, including gastrointestinal disorders. Although there is no cure for PD, symptomatic treatments are available. L-Dopa is the go...