Sex as a biological variable (SABV) modulates the consequences of sleep disturbance on hippocampal memory and synaptic plasticity [0.03%]
性别的生物变量调节睡眠紊乱对海马记忆和突触可塑性的影响
Camilla Paraciani,Robbert Havekes,Peter Meerlo et al.
Camilla Paraciani et al.
Sleep disturbance affects brain health, with research in rodents showing that both hippocampal memory and synaptic plasticity are impaired following sleep deprivation (SD). However, most studies have used males, overlooking sex as a biologi...
Evangelia Zapanti,Alexandros Dermentzoglou,Paraskevi Kazakou et al.
Evangelia Zapanti et al.
Multiple sclerosis (MS) is the commonest autoimmune inflammatory neurological disease presenting multifocal demyelinating lesions in the white matter of the central nervous system (CNS). Its pathogenesis involves genetic and environmental m...
The overlooked mental health burden of polycystic ovary syndrome: neurobiological insights into PCOS-related depression [0.03%]
多囊卵巢综合征的心理健康负担被忽视：PCOS相关抑郁的神经生物学见解
Eleni Dubé-Zinatelli,Freya Anderson,Nafissa Ismail
Eleni Dubé-Zinatelli
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting 6-13% of reproductive-aged women worldwide. It is primarily characterized by ovarian dysfunction, hyperandrogenism, and metabolic disturbances. However, women with...
Silvia Elisabetta Portis Bruzzone,Victoria Frederikke S Garre,Stinne Høgh et al.
Silvia Elisabetta Portis Bruzzone et al.
Perinatal depression (PD) is a major public mental health problem affecting 10-20% of pregnant women. Women undergo profound biological and psychosocial adaptations during pregnancy and the postpartum period. Measures of genomic function ca...
Oxytocin and dopamine in psychostimulant-induced changes in social behaviour [0.03%]
催产素和多巴胺在兴奋剂诱导的行为改变中的作用
Fernando Castillo Díaz,Inga D Neumann,Virginie Rappeneau
Fernando Castillo Díaz
Oxytocin (OXT) plays a significant role in regulating social behaviour across various species, making it a key focus in neuroscience. Recent research has expanded beyond the established prosocial effects of OXT to explore its complex interp...
J Leigh Leasure,Catherine E Van Doorn,Kimberly Nixon
J Leigh Leasure
Aging and alcohol exert marked effects on the endocrine system - in particular the hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-adrenal (HPA) axes. The aging female brain represents a unique substrate for alcohol effects,...
Anja C Feneberg,Susanne Fischer,Nadine Skoluda
Anja C Feneberg
Hair cortisol concentration (HCC) is a crucial biomarker in psychoneuroendocrinological research, offering unique insights into long-term hypothalamic-pituitary-adrenal axis activity. Season has repeatedly shown associations with HCC. Howev...
History of hypertensive disorders of pregnancy and risk of Alzheimer's disease and vascular dementia [0.03%]
妊娠高血压疾病史与阿尔茨海默病和血管性痴呆发病风险的关系
Simranjit Kaur,Chauncey J Darden,Goodness M Adegbola et al.
Simranjit Kaur et al.
The incidence of dementia, and specifically, Alzheimer's disease, is higher in women than men, even in middle age, making it possible to rule out lifespan differences between men and women as a contributing factor. Thus, it is plausible tha...
The medial amygdala's neural circuitry: Insights into social processing and sex differences [0.03%]
杏仁体内侧核团的神经环路及其在社交行为及性别差异中的作用机制研究进展
Benavides Ignacio,Janina Baeza,Bastián Ruiz et al.
Benavides Ignacio et al.
The amygdala, a critical part of the limbic system, is essential for processing social stimuli and regulating stress responses. Among its various neuronal nuclei, the medial amygdala (MeA) remains one of the least studied in humans. The MeA...
Physical activity in Alzheimer's disease prevention: Sex differences and the roles of BDNF and irisin [0.03%]
阿尔茨海默病的预防：性别差异和脑源性神经营养因子及鸢尾素的作用
F G Q Barros-Aragão,E Januszkiewicz,T Hunter et al.
F G Q Barros-Aragão et al.
Alzheimer's disease (AD) disproportionately affects women, with postmenopausal hormonal changes contributing to elevated risk. Physical exercise is a promising, non-pharmacological strategy to mitigate cognitive decline and AD progression. ...