Central and peripheral neuropeptide RFRP-3: A bridge linking reproduction, nutrition, and stress response [0.03%]
神经肽RFRP-3：联系生殖、营养和应激反应的中枢与外周介质
Padmasana Singh,Shabana Anjum,Raj Kamal Srivastava et al.
Padmasana Singh et al.
This article is an amalgamation of the current status of RFRP-3 (GnIH) in reproduction and its association with the nutrition and stress-mediated changes in the reproductive activities. GnIH has been demonstrated in the hypothalamus of all ...
Timing is everything: Circadian rhythms and their role in the control of sleep [0.03%]
时机决定成败：生物钟在睡眠调控中的作用
Seithikurippu R Pandi-Perumal,Daniel P Cardinali,Nevin F W Zaki et al.
Seithikurippu R Pandi-Perumal et al.
Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endoge...
Takayoshi Ubuka,Kazuyoshi Tsutsui
Takayoshi Ubuka
Neurosteroids are steroids synthesized within the central nervous system either from cholesterol or by metabolic reactions of circulating steroid hormone precursors. It has been suggested that neurosteroids exert pleiotropic activities with...
Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research [0.03%]
神经激肽B受体系统的生物学功能及其作为药理学靶点的潜力
Veronica Sobrino,Maria Soledad Avendaño,Cecilia Perdices-López et al.
Veronica Sobrino et al.
In late 2003, a major breakthrough in our understanding of the mechanisms that govern reproduction occurred with the identification of the reproductive roles of kisspeptins, encoded by the Kiss1 gene, and their receptor, Gpr54 (aka, Kiss1R)...
The hypothalamic paraventricular nucleus as a central hub for the estrogenic modulation of neuroendocrine function and behavior [0.03%]
垂体束核是雌激素调节神经内分泌功能和行为的中枢节点
D Grassi,M Marraudino,L M Garcia-Segura et al.
D Grassi et al.
Estradiol and hypothalamic paraventricular nucleus (PVN) help coordinate reproduction with body physiology, growth and metabolism. PVN integrates hormonal and neural signals originating in the periphery, generating an output mediated both b...
Perinatal mental illness and maternal autoimmune disease: A review of current evidence and avenues for future research [0.03%]
围产期精神疾病与母体自身免疫病：现有证据及未来研究方向综述
Hilary K Brown,Kathryn Barrett,Natalie V Scime
Hilary K Brown
This review summarizes evidence on the association between perinatal mental illness and maternal autoimmune disease and identifies avenues for future research. Perinatal mental illness has several characteristics in common with autoimmune d...
Jeremy A Spool,Joseph F Bergan,Luke Remage-Healey
Jeremy A Spool
This review explores the role of aromatase in the brain as illuminated by a set of conserved network-level connections identified in several vertebrate taxa. Aromatase-expressing neurons are neurochemically heterogeneous but the brain regio...
How exposure to chronic stress contributes to the development of type 2 diabetes: A complexity science approach [0.03%]
慢性压力暴露如何促发2型糖尿病发病：复杂科学方法透视
Nadège Merabet,Paul J Lucassen,Loes Crielaard et al.
Nadège Merabet et al.
Chronic stress contributes to the onset of type 2 diabetes (T2D), yet the underlying etiological mechanisms are not fully understood. Responses to stress are influenced by earlier experiences, sex, emotions and cognition, and involve a comp...
Intermittent fasting and cognitive performance - Targeting BDNF as potential strategy to optimise brain health [0.03%]
间歇性禁食与认知表现-BDNF作为优化脑健康潜力策略的目标
Karin Seidler,Michelle Barrow
Karin Seidler
Aging is the major risk factor for neurodegenerative diseases, accelerated by excessive calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent fasting (IF) have shown to promote lifespan and healthspan vi...
A scoping review of resting-state brain functional alterations in Type 2 diabetes [0.03%]
2型糖尿病休息态脑功能改变的系统综述研究
Anson C M Chau,Ashleigh E Smith,Brenton Hordacre et al.
Anson C M Chau et al.
Resting-state functional magnetic resonance imaging (rs-fMRI) has been actively used in the last decade to investigate brain functional connectivity alterations in Type 2 Diabetes Mellitus (T2DM) to understand the neuropathophysiology of T2...