What is there to know about the effects of progestins on the human brain and cognition? [0.03%]
孕激素对人脑和认知的作用有哪些?
Ramune Griksiene,Rasa Monciunskaite,Osvaldas Ruksenas
Ramune Griksiene
Progestins are an important component of hormonal contraceptives (HCs) and hormone replacement therapies (HRTs). Despite an increasing number of studies elucidating the effects of HCs and HRTs, little is known about the effects of different...
Imaging the human brain on oral contraceptives: A review of structural imaging methods and implications for future research goals [0.03%]
口服避孕药的人脑影像学:结构影像方法的综述及对未来研究目标的意义
Carina Heller,Ann-Christin S Kimmig,Marek R Kubicki et al.
Carina Heller et al.
Worldwide over 150 million women use oral contraceptives (OCs), which are the most prescribed form of contraception in both the United States and in European countries. Sex hormones, such as estradiol and progesterone, are important endogen...
The impact of hormonal contraceptives on anxiety treatments: From preclinical models to clinical settings [0.03%]
激素避孕药对焦虑症治疗的影响:从基础模型到临床应用
Bronwyn M Graham
Bronwyn M Graham
Exposure therapy is a central component of the first-line treatment for anxiety disorders, a common mental health condition that is twice as prevalent in women relative to men. A key underlying mechanism of exposure therapy is fear extincti...
Modeling hormonal contraception in female rats: A framework for studies in behavioral neurobiology [0.03%]
大鼠激素避孕的建模:行为神经生物学研究的一个框架
Jesse M Lacasse,Eamonn Gomez-Perales,Wayne G Brake
Jesse M Lacasse
Research on hormonal contraceptives (HC) in animal models is lacking, and as a result, so is our understanding of the impact of HC on the brain and behavior. Here, we provide a review of the pharmacology of HC, as well as the methodology an...
Paroxetine combined with traditional chinese medicine prescriptions in the treatment of postpartum depression: A systematic review of randomized controlled trials [0.03%]
帕罗西汀联合中药治疗产后抑郁症的随机对照试验系统评价研究
Mengjie Zeng,Aimin Gong,Zhiquan Wu
Mengjie Zeng
Background: Postpartum depression is a common mental disease in obstetric puerperium. Its etiology is not completely clear, and its clinical manifestations are complex. It has serious adverse effects on the body and mind ...
Pituitary multi-hormone cells in mammals and fish: history, origin, and roles [0.03%]
哺乳动物和鱼类的垂体多激素细胞:历史、起源与作用
Romain Fontaine,Muhammad Rahmad Royan,Christiaan Henkel et al.
Romain Fontaine et al.
The vertebrate pituitary is a dynamic organ, capable of adapting its hormone secretion to different physiological demands. In this context, endocrinologists have debated for the past 40 years if endocrine cells are mono- or multi-hormonal. ...
Varun Reddy,Megan Wurtz,Shahil H Patel et al.
Varun Reddy et al.
Incidents of strokes are increased in young women relative to young men, suggesting that oral contraceptive (OC) use is one of the causes of stroke among young women. Long-term exposures to the varying combinations of estrogen and progestog...
How hormonal contraceptives shape brain and behavior: A review of preclinical studies [0.03%]
激素避孕药对脑和行为的影响:一项对非临床研究的回顾
Alessandra Concas,Mariangela Serra,Patrizia Porcu
Alessandra Concas
Steroid hormones influence different aspects of brain function, including development, neurogenesis, neuronal excitability, and plasticity, thus affecting emotional states, cognition, sociality, and reward. In women, their levels fluctuate ...
Hormonal contraceptives as disruptors of competitive behavior: Theoretical framing and review [0.03%]
激素避孕药干扰竞争行为的理论框架和综述
Lindsie C Arthur,Kathleen V Casto,Khandis R Blake
Lindsie C Arthur
Emerging evidence suggests that hormonal contraceptives (HCs) impact psychological outcomes through alterations in neurophysiology. In this review, we first introduce a theoretical framework for HCs as disruptors of steroid hormone modulati...
The critical impact of sex on preclinical alcohol research - Insights from zebrafish [0.03%]
性别对预临床酒精研究的关键影响——斑马鱼的启示
Murilo S de Abreu,Matthew O Parker,Allan V Kalueff
Murilo S de Abreu
Sex is an important biological variable that is widely recognized in studies of alcohol-related effects. Complementing clinical and preclinical rodent research, the zebrafish (Danio rerio) is the second most used laboratory species, and a p...