Women's use of alcohol: Neurobiobehavioral concomitants and consequences [0.03%]
女性饮酒的相关神经行为伴随物及后果研究进展
Sara Jo Nixon,Christian C Garcia,Ben Lewis
Sara Jo Nixon
In this narrative review, we draw from historical and contemporary literature to explore the impact of alcohol consumption on brain and behavior among women. We examine three domains: 1) the impact of alcohol use disorder (AUD) on neurobiob...
Vitamin D status and cognitive performance in community-dwelling adults: A dose-response meta-analysis of observational studies [0.03%]
维生素D水平与社区居住成年人的认知表现：观察性研究的剂量反应型meta分析
Janis D Harse,Ross J Marriott,Kun Zhu et al.
Janis D Harse et al.
Low vitamin D status is linked with poorer cognition in adults while findings in relation to high levels are mixed.We performed a systematic review and meta-analyses to examine dose-response associations between 25-hydroxyvitamin D (25OHD) ...
The Role of the Gut Microbiome in Bipolar Disorder and its Common Medical Comorbidities [0.03%]
肠道微生物组在双相情感障碍及其常见共病中的作用
Gregory H Jones,Omar F Pinjari,Courtney M Vecera et al.
Gregory H Jones et al.
Bipolar disorder is a decidedly heterogeneous and multifactorial disease, with significant psychosocial and medical disease burden. Much difficulty has been encountered in developing novel therapeutics and objective biomarkers for clinical ...
Women are taking the hit: Examining the unique consequences of cannabis use across the female lifespan [0.03%]
女性受创：跨生命周期大麻使用的独特后果研究
E L Gräfe,H M O Reid,I Shkolnikov et al.
E L Gräfe et al.
Cannabis use has risen dramatically in recent years due to global decriminalization and a resurgence in the interest of potential therapeutic benefits. While emerging research is shaping our understanding of the benefits and harms of cannab...
Neuroendocrine mechanisms contributing to the coevolution of sociality and communication [0.03%]
神经内分泌机制促进了社交和交流的协同进化
Megan K Freiler,G Troy Smith
Megan K Freiler
Communication is inherently social, so signaling systems should evolve with social systems. The 'social complexity hypothesis' posits that social complexity necessitates communicative complexity and is generally supported in vocalizing mamm...
Fast neurotransmitter identity of MCH neurons: Do contents depend on context? [0.03%]
快速神经递质身份的MCH神经元：内容取决于上下文吗？
B G Beekly,A Rupp,C R Burgess et al.
B G Beekly et al.
Hypothalamic melanin-concentrating hormone (MCH) neurons participate in many fundamental neuroendocrine processes. While some of their effects can be attributed to MCH itself, others appear to depend on co-released neurotransmitters. Histor...
Hormonal contraception and cognition: Considering the influence of endogenous ovarian hormones and genes for clinical translation [0.03%]
激素避孕与认知：考虑内源性卵巢激素和基因的临床转化的影响
Laura Gravelsins,Sophia Zhao,Gillian Einstein
Laura Gravelsins
Despite the well-known influence of ovarian hormones on the brain and widespread use of hormonal contraception (HC) since the 1960s, our knowledge of HC's cognitive effects remains limited. To date, the cognitive findings have been inconsis...
Cardiometabolic health, menopausal estrogen therapy and the brain: How effects of estrogens diverge in healthy and unhealthy preclinical models of aging [0.03%]
心血管健康、绝经期雌激素疗法和大脑：雌激素效应在健康的和不健康的衰老小鼠模型中的差异性研究
Jill M Daniel,Sarah H Lindsey,Ricardo Mostany et al.
Jill M Daniel et al.
Research in preclinical models indicates that estrogens are neuroprotective and positively impact cognitive aging. However, clinical data are equivocal as to the benefits of menopausal estrogen therapy to the brain and cognition. Pre-existi...
Targeting the orexin/hypocretin system for the treatment of neuropsychiatric and neurodegenerative diseases: From animal to clinical studies [0.03%]
靶向食欲素/下丘脑素系统治疗神经精神及神经退行性疾病：从动物实验到临床研究
Marc Ten-Blanco,África Flores,Luigia Cristino et al.
Marc Ten-Blanco et al.
Orexins (also known as hypocretins) are neuropeptides located exclusively in hypothalamic neurons that have extensive projections throughout the central nervous system and bind two different G protein-coupled receptors (OX1R and OX2R). Sinc...
Stress in adolescence as a first hit in stress-related disease development: Timing and context are crucial [0.03%]
青春期压力作为应激相关疾病发展的第一次打击：时机和情境至关重要
Giulia F Mancini,Onno C Meijer,Patrizia Campolongo
Giulia F Mancini
The two-hit stress model predicts that exposure to stress at two different time-points in life may increase or decrease the risk of developing stress-related disorders later in life. Most studies based on the two-hit stress model have inves...