Balancing energy expenditure and storage with growth and biosynthesis during Drosophila development [0.03%]
在果蝇发育过程中平衡能量消耗和储存与生长和生物合成的关系
Claire M Gillette,Jason M Tennessen,Tânia Reis
Claire M Gillette
Sustaining life requires efficient uptake of nutrients and conversion to useable forms. Almost everything about this process is dynamic. Nutrient availability fluctuates and changing environmental conditions impose new demands that can tip ...
The Pebble/Rho1/Anillin pathway controls polyploidization and axonal wrapping activity in the glial cells of the Drosophila eye [0.03%]
果蝇眼睛类神经细胞的多倍体化和轴突包绕活性由Pebble/Rho1/Anillin信号通路控制
Lígia Tavares,Patrícia Grácio,Raquel Ramos et al.
Lígia Tavares et al.
During development glial cell are crucially important for the establishment of neuronal networks. Proliferation and migration of glial cells can be modulated by neurons, and in turn glial cells can differentiate to assume key roles such as ...
Haruko Nakano,Viviana M Fajardo,Atsushi Nakano
Haruko Nakano
Cells display distinct metabolic characteristics depending on its differentiation stage. The fuel type of the cells serves not only as a source of energy but also as a driver of differentiation. Glucose, the primary nutrient to the cells, i...
VEGF signaling activates the matrix metalloproteinases, MmpL7 and MmpL5 at the sites of active skeletal growth and MmpL7 regulates skeletal elongation [0.03%]
VEGF信号激活生长活跃部位的基质金属蛋白酶MmpL7和MmpL5的作用并调控骨骼伸长
Miri Morgulis,Mark R Winter,Ligal Shternhell et al.
Miri Morgulis et al.
Organisms can uptake minerals, shape them in different forms and generate teeth, skeletons or shells that support and protect them. Mineral uptake, trafficking and nucleation are tightly regulated by the biomineralizing cells through networ...
Control of the ecdysteroid level plays a crucial role in density-dependent metamorphosis in the giant mealworm beetle Zophobas atratus [0.03%]
泛化代谢的密度依赖性调控——蜕皮甾醇在大麦蛾斑粉虫发育中的作用
Kouhei Toga,Yuri Homma,Toru Togawa
Kouhei Toga
Metamorphic transition in some tenebrionid beetles is dependent on population density. This phenomenon is useful for pupae that are vulnerable to cannibalism. The physiological mechanism of this adaptive developmental phenomenon remains unc...
Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids [0.03%]
利用成人内胚层组织衍生的类器官鉴定新的人类Wnt靶基因
Kim Elisabeth Boonekamp,Inha Heo,Benedetta Artegiani et al.
Kim Elisabeth Boonekamp et al.
Canonical Wnt signaling plays a key role during organ development, homeostasis and regeneration and these processes are conserved between invertebrates and vertebrates. Mutations in Wnt pathway components are commonly found in various types...
Developmental plasticity and the response to nutrient stress in Caenorhabditis elegans [0.03%]
发育可塑性与营养缺乏胁迫在秀丽隐杆线虫中的响应机制研究进展
Sabih Rashid,Christopher Wong,Richard Roy
Sabih Rashid
Developmental plasticity refers the ability of an organism to adapt to various environmental stressors, one of which is nutritional stress. Caenorhabditis elegans require various nutrients to successfully progress through all the larval sta...
Integrating animal development: How hormones and metabolism regulate developmental transitions and brain formation [0.03%]
整合动物发育：激素和代谢如何调节发育过渡和大脑形成
Andreia C Oliveira,Ana R Rebelo,Catarina C F Homem
Andreia C Oliveira
Our current knowledge on how individual tissues or organs are formed during animal development is considerable. However, the development of each organ does not occur in isolation and thus their formation needs to be done in a coordinated ma...
Debadrita Bhattacharya,Behram Khan,Marcos Simoes-Costa
Debadrita Bhattacharya
The neural crest is a migratory stem cell population that contributes to various tissues and organs during vertebrate embryonic development. These cells possess remarkable developmental plasticity and give rise to many different cell types,...
Diya B Joseph,Anne E Turco,Chad M Vezina et al.
Diya B Joseph et al.
The prostate develops by epithelial budding and branching processes that occur during fetal and postnatal stages. The adult prostate demonstrates remarkable regenerative capacity, with the ability to regrow to its original size over multipl...