Discrete 3' UTR sequence motifs regulate nanos RNA enrichment in Drosophila germ granules [0.03%]
离散的3'UTR序列基元调节NanosRNA在果蝇原生质颗粒中的富集作用
Kira Mitchel,Elizabeth R Gavis
Kira Mitchel
Germ granules are ribonucleoprotein condensates that concentrate key maternal mRNAs needed for germ cell development. In Drosophila, nanos mRNA is selectively enriched in germ granules but the specific cis-acting elements mediating this pro...
The roles of TGFβ and serotonin signaling in regulation of germline progenitors in adult C. elegans hermaphrodites revealed by the effects of a male pheromone [0.03%]
通过雄性信息素影响揭示秀丽隐杆线虫成年雌雄同体生殖干细胞调控中的TGFβ和血清素信号的作用
Erin Z Aprison,Svetlana Dzitoyeva,Ilya Ruvinsky
Erin Z Aprison
Some developmental processes initiated in embryos or larvae persist into adulthood, a prominent example being maintenance of stem cells. To what extent are the mechanisms regulating these cell populations similar during different stages of ...
Madison Zitting,Zhou Yu,Ting-Xin Jiang et al.
Madison Zitting et al.
Bioelectricity plays a key role in shaping tissues during early development. We previously demonstrated that elongating chicken feather buds establish a transient standing electrical current loop, with calcium channel-mediated inward curren...
Adipocyte-derived amino acid storage proteins are required for germline stem cell maintenance in adult Drosophila females [0.03%]
脂肪细胞来源的氨基酸储存蛋白是成年果蝇雌性生殖干细胞维持所必需的蛋白质
Anna B Zike,Mekenzi O Hazen,Madison G Abel et al.
Anna B Zike et al.
Tissue homeostasis is dependent on precise coordination between endocrine organs in response to changes in organism physiology. Secreted circulating factors from adipocytes regulate the behavior of stem cell lineages in peripheral tissues i...
E.G. Conklin's support for the mosaic mode of development and understanding the role of maternal determinants [0.03%]
E.G.康林对镶嵌式发育模式的支持以及对母体决定因子作用的理解
Steven L Klein,Sally A Moody
Steven L Klein
In 1905, the American embryologist, Edwin Grant Conklin published three landmark papers that substantially influenced the fields of developmental biology and evolution. They described the development of ascidian embryos, focusing on cleavag...
Brenda J Mengeling,J David Furlow
Brenda J Mengeling
Across the animal kingdom, many developmental programs require retinoid X receptor (RXR) expression. RXR is a unique member of the nuclear receptor (NRs) superfamily of transcription factors. Most famously, it serves as a mandatory heterodi...
Genes for 5'mRNA cap binding proteins, eif4ea and eif4eb, have alternative roles during heart regeneration [0.03%]
心脏再生过程中与5' mRNA帽结合蛋白eif4ea和eif4eb相关基因的替代作用
Rejenae Dockery,Mateo Zevallos,Carson McNulty et al.
Rejenae Dockery et al.
All eukaryotes possess the essential mRNA cap-binding protein eIF4E, which initiates translation. This protein is highly conserved, with versions from zebrafish and humans able to rescue yeast. All fish also have an ancestral eIF4E family, ...
Shrew is an essential, recently evolved, Drosophila specific gene required for formation of the embryonic BMP activity gradient [0.03%]
虾状虫是一种本质的、最近进化的、果蝇特异性的基因，对于胚胎BMP活性梯度形成是必需的
MaryJane Shimell,Robert Connacher,Sangbin Park et al.
MaryJane Shimell et al.
Patterning the dorsal surface of the Drosophila blastoderm embryo requires the rapid redistribution of a BMP heterodimer (Decapentaplegic/Screw) from lateral regions of the embryo to the dorsal midline as cellularization is completed. BMP r...
Cortical hem-like progenitors contribute pyramidal neurons to the neocortex and hippocampus [0.03%]
脑皮层镰状祖细胞向新皮质和海马区贡献锥体神经元
Arpan Parichha,Patrick Azzam,Frederic Causeret et al.
Arpan Parichha et al.
The cortical hem is a signaling center at the midline of the embryonic telencephalon that provides instructive cues to the adjacent cortical primordium and serves as the hippocampal organizer, inducing multiple distinct hippocampal field id...
Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown [0.03%]
甲状腺激素在两栖类变态中的信号传导和调节的分子及基因研究（贾姆舍德塔塔和唐纳德布朗的贡献）
Salomé Nashed,Emeric Louis,Nicolas Buisine et al.
Salomé Nashed et al.
Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches maturation. Amphibian metamorphosis represents one of the most extreme examples of post-embryonic transition. In Anu...