The ovarian structure and oogenesis in the Podarcis siculus lizard: a comprehensive overview spanning over sixty years [0.03%]
六十年来关于Podarcis siculus蜥蜴卵巢结构和卵生成的综合概述
Rosaria Scudiero,Teresa Chianese,Marina Prisco et al.
Rosaria Scudiero et al.
Oogenesis in oviparous vertebrates begins with a clustered gonad, a structure that may appear simple at first glance, but which conceals a certain complexity in the differentiation of follicles and the maturation of germ cells. The primordi...
How does a tadpole know when to metamorphose? Integrating evolutionary, ecological, and developmental biology with the neuroendocrinology of amphibian metamorphosis [0.03%]
蝌蚪何时变态的判断机制：整合进化生态学、发育生物学与两栖动物变态过程的神经内分泌学
Robert J Denver
Robert J Denver
Amphibian metamorphosis is an excellent model for studying how selective pressures, environmental cues, endocrine signals, and molecular mechanisms influence developmental timing. In this minireview, I discuss key questions about the timing...
Detecting correlations, generating hypotheses, and avoiding pitfalls in analyzing timeseries in developmental biology [0.03%]
发育生物学中时间序列的相关性检测、假设生成及分析陷阱规避
Denis F Faerberg,Victor Gurarie,Ilya Ruvinsky
Denis F Faerberg
Currently available experimental approaches enable monitoring trait dynamics in singled individuals. One important advantage of individually resolved data is the ability to reveal correlations that can provide insights into regulatory proce...
The Dual Function Model Revisited by Thyroid Hormone Receptor Knockouts: Unliganded state controlling the initiation of adult organ development while liganded state ensuring larval tissue resorption during metamorphosis [0.03%]
甲状腺激素受体基因敲除小鼠重新诠释下垂体-甲状腺-性腺双重功能模型：未结合状态下控制成年器官发育的启动，而结合状态下则确保变态过程中幼虫组织的吸收
Daniel R Buchholz,Yun-Bo Shi
Daniel R Buchholz
Thyroid hormone (T3) plays a critical role in vertebrate development, particularly in postembryonic organ remodeling and maturation. Plasma level of T3 peaks during postembryonic development, which corresponds to the neonatal period in mamm...
Linkages between BMP, canonical WNT/β-catenin, and FGF20 Signaling during Placode Formation in the Chicken Anterior Eye Segment [0.03%]
鸡前眼段视泡形成期间BMP、经典WNT/β-catenin和FGF20信号通路之间的相互作用
Aveeva Herold,Tamara A Franz-Odendaal
Aveeva Herold
The mechanisms that regulate the even spacing of placodes during embryonic development remain intriguing. These mechanisms typically involve complex interactions between signaling pathways, which can be further influenced by mechanical forc...
Vnd and En are expressed in orthogonal stripes and act in a brief competence window to combinatorially specify NB7-1 and its early lineage [0.03%]
Vnd和En在正交条纹中表达，并在一个短暂的反应窗口期协同作用以组合方式指定NB7-1及其早期谱系
Nathan L Q Anderson,Sen-Lin Lai,Chris Q Doe
Nathan L Q Anderson
Understanding how neuronal diversity is generated is a major goal of neuroscience. Here we characterize the first step in generating neuronal diversity in the Drosophila embryo: spatial transcription factors (STFs) expressed in orthogonal r...
SWI/SNF ATPase Brahma and Notch signaling collaborate with CBP/p300 to regulate neural stem cell apoptosis in Drosophila larval central nervous system [0.03%]
SWI/SNF家族成员Brahma和Notch信号通路在果蝇幼虫中枢神经系统中与CBP/P300一起调节神经干细胞凋亡
Punam Bala,Viswadica Prakki,Rohit Joshi
Punam Bala
SWI-SNF ATPase Brahma and Notch signalling are known to interact during development, but how this interaction is executed at the molecular level is not fully understood. We have investigated the molecular mechanism of Brm-Notch interaction ...
Primary cilia and BBS4 are required for postnatal pituitary development [0.03%]
主纤毛和BBS4是产后垂体发育所需的因素
Kathryn M Brewer,Katlyn K Brewer,Nicholas C Richardson et al.
Kathryn M Brewer et al.
Primary cilia orchestrate several signaling pathways, and their disruption results in pleiotropic disorders called ciliopathies. Bardet-Beidl syndrome (BBS), one ciliopathy, provides insights into cilia function in many tissues. Using a mou...
An inducible system to study the regulatory functions of GSX2 in human lateral ganglionic eminence-like progenitors [0.03%]
研究GSX2在人类侧脑室下带类祖细胞中的调控功能的诱导系统
Edward Farrow,Smitha Rao,Simon J Y Han et al.
Edward Farrow et al.
Animal models have demonstrated a critical role of the homeodomain transcription factor Genetic-Screened Homeobox 2 (Gsx2) in the developing basal ganglia. Moreover, recent clinical genetic studie...