FGF signalling orchestrates multiple roles during salivary gland branching morphogenesis [0.03%]
FGF信号在唾液腺分支形态发生过程中统筹多种作用
Marta Perera,Decheng Kong,Joshua M Brickman et al.
Marta Perera et al.
The function of the organs in our body is intrinsically related to their form, acquired during embryonic development. Many epithelial organs such as lung, kidney, pancreas or salivary glands branch during morphogenesis to optimise the avail...
RNA-binding proteins in the mouse lens: Functional classifications, expression profiling, and interaction studies of Carhsp1 with crystallin mRNAs [0.03%]
小鼠晶状体中的RNA结合蛋白：Carhsp1与结晶蛋白mRNA的相互作用及功能分类和表达谱分析
Danielle Rayêe,Dong-Woo Hwang,William K Chang et al.
Danielle Rayêe et al.
RNA-binding proteins (RBPs) are critical regulators of mRNAs controlling all processes such as RNA transcription, transport, localization, translation, mRNA:ncRNA interactions, and decay. Cellular differentiation is driven by temporally and...
Nagif Alata-Jimenez,Marcos Simoes-Costa
Nagif Alata-Jimenez
The chicken embryo has been a central model in developmental biology for centuries, prized for its experimental tractability and the ease with which embryonic tissues can be directly observed and manipulated. Its external development allows...
⍺TAT1-dependent microtubule acetylation is required for touch sensation in zebrafish but not for cilia-driven morphogenesis [0.03%]
斑马鱼的触觉感应需要微管乙酰化酶TAT1，但其对于纤毛驱动的形态发生过程并非必需
Samuel G Bertrand,Daniel T Grimes
Samuel G Bertrand
Acetylation of ⍺-tubulin at lysine 40 (⍺-tubK40Ac) is a conserved post-translational modification enriched on long-lived microtubules, yet its roles in vertebrate development remain incompletely defined. In zebrafish, morpholino-based kno...
Wnt4 as a signal coordinates DNA methylation and acetylation to determine germ line fate [0.03%]
Wnt4信号协调DNA甲基化和乙酰化以决定生殖细胞命运
Florence Naillat,Shin-Ichi Tomizawa,Elena Ivanova et al.
Florence Naillat et al.
Wnt4 signaling promotes somatic cell development in the female embryo, but its role in germline differentiation during meiosis remains poorly characterized. To explore Wnt4 functions in female embryonic gonads, we isolated germ cells from W...
The microcephaly protein Abnormal Spindle has an essential role in symmetrically dividing neural precursors to promote brain growth and development [0.03%]
微小头蛋白异常纺锤体在神经前体的对称分裂中具有重要作用以促进脑生长和发育
Shalini Chakraborty,Steven Florez,Jack Govaerts et al.
Shalini Chakraborty et al.
Neurogenesis must be coordinated in time and space to ensure proper neural development. Defects in this process can lead to a variety of brain malformations that affect tissue size and architecture. Here we examine the spatiotemporal requir...
Hungarian mummies of the White Plague: homeotic transformation in a historic epidemic [0.03%]
匈牙利白瘟疫木乃伊的遗传变异分析及形态转变研究
Kate Windsor
Kate Windsor
Mikayla Eppert
Mikayla Eppert
Brenda Pardo
Brenda Pardo
Meis1 and Meis2 are jointly required for advanced stages of mouse lens morphogenesis [0.03%]
Meis1和Meis2是小鼠晶状体发生晚期阶段的必需条件
Jana Smolikova,Barbora Antosova,Jitka Lachova et al.
Jana Smolikova et al.
The TALE homeodomain transcription factors Meis1 and Meis2 are broadly co-expressed during vertebrate organogenesis. They serve as critical regulators of early mouse lens morphogenesis at the lens placodal stage; however, their cooperative ...