Cambria Chou-Freed,Christopher K Prinz,Anush Margaryan et al.
Cambria Chou-Freed et al.
Intracellular pH (pHi) dynamics regulates numerous cellular processes, including migration and proliferation. While these functions are well-established in cell lines, the role of pHi changes in vivo is less well understood. We generated a ...
Coming full circle: Neural crest marker FOXD3 regulates SHH expression in the floorplate and neural tube morphogenesis [0.03%]
循环往复：神经嵴标志物FOXD3调控底板SHH表达及神经管形态发生
Jenaid Rees,Ed Zandro Taroc,Karla Barbosa-Sabanero et al.
Jenaid Rees et al.
Background: The unique nature of neural crest cells has encouraged the characterization of the dorsal neural tube as distinct from the rest of the neural tube. Yet the dorsal and ventral neural tube have several similarit...
The oocytes of basal dermapterans lack the posterior pole lysosomal compartment (PPLC) [0.03%]
基础蠼螋类昆虫的卵细胞缺乏后极溶酶体区室(PPLC)
Szczepan M Bilinski,Magda Sochaczewska,Paula Irles et al.
Szczepan M Bilinski et al.
In the parallel paper (Sochaczewska et al., 2026; this issue), we have shown that in advanced dermapterans (the Eudermaptera), all lysosome-like bodies/organelles present in the oocyte and associated nurse cell are transferred to the poster...
A central role for Islr2 (Linx) in direct pathway striatal projection neurons for the correct formation of the internal capsule and cerebral peduncle [0.03%]
Islr2（Linx）在直接通路纹状体投射神经元中的核心作用及其正确形成内囊和脑脚的作用研究
Saima Ali,Jacqueline M Ehrman,Paloma Merchan-Sala et al.
Saima Ali et al.
Islr2 (Linx) is a transmembrane protein that mediates correct formation of the internal capsule/cerebral peduncle. Here, we have utilized a combination of transgenic reporter alleles and immunohistochemical markers to trace striatal direct ...
Shared candidate genes associated with variation in egg size in cold-adapted and artificially selected Drosophila melanogaster [0.03%]
与冷适应和人工选择的果蝇品系蛋大小变异相关的共同候选基因
Intisar Koch,Taylor Beagle,Tyler Hayes et al.
Intisar Koch et al.
The development of most multicellular organisms begins with oogenesis, the production of the egg. In D. melanogaster, egg size is a highly polygenic trait closely related to fitness. Elements of shifts in egg size have been widely studied a...
The molecular mechanism underlying melatonin-mediated repair of ovarian damage in mice exposed to abnormal light cycles [0.03%]
异常光照下小鼠卵巢损伤的褪黑素修复机制研究
Fangdi Zhang,Ruixue Ma,Yadan Jin et al.
Fangdi Zhang et al.
This study aimed to investigate the molecular mechanisms by which melatonin (MLT) mitigates ovarian damage in mice exposed to abnormal light cycles. Female C57BL/6 mice from the same batch were randomly assigned to five experimental groups:...
The Drosophila ovarian terminal filament imports lipophilic molecules that support cyst and follicle development within the ovariole [0.03%]
果蝇卵巢终末指状物转运脂溶性分子以支持卵泡小室内的囊细胞和卵泡发育
Bhawana Maurya,Allan C Spradling
Bhawana Maurya
Oogenesis in Drosophila requires small molecules as biosynthetic precursors and regulators of follicle development. But how such molecules reach germline stem cells (GSCs), developing germline cysts and follicles in the germarium and early ...
Secreted Frizzled-Related Protein 1 Controls Distal Lung Formation via Wnt and PDGF Signaling [0.03%]
分泌型卷曲相关蛋白1通过Wnt和PDGF信号控制远端肺的形成
Nooralam A Rai,Tina Zelonina,Kiran Chada et al.
Nooralam A Rai et al.
Rationale: Normal lung development is an intricate process that depends on temporally regulated mesenchymal signaling to coordinate structural maturation, cell differentiation, and extracellular matrix organization. How e...
The vascular-osteogenic interface in craniofacial development: a structured review of emerging associations in congenital malformations [0.03%]
颅面发育中的血管成骨界面：先天畸形中新兴关联的结构化综述
Karl Jacobs,Fatima Miry,Hedwig van der Meer et al.
Karl Jacobs et al.
Craniofacial skeletal morphogenesis depends on tightly coordinated interactions between vascular development and osteogenesis. Although congenital craniofacial malformations are traditionally conceptualized as bone-intrinsic disorders, emer...
Turning off metamorphosis: Thyroid hormone deregulation in the evolution of obligately paedomorphic salamanders [0.03%]
蜕变关闭：甲状腺激素调节在演化中的必需幼态持续的蝾螈中的失调
Ronald M Bonett,Samantha D Trame
Ronald M Bonett
Amphibian metamorphosis is a dramatic thyroid hormone (TH) mediated process involving the transformation of aquatic larvae into more-terrestrial adults. But some salamanders, referred to as larval-form paedomorphs, completely or partially f...