EGFR upregulates inflammatory and proliferative responses in human lung adenocarcinoma cell line (A549), induced by lower dose of cadmium chloride [0.03%]
低剂量氯化镉诱导的人肺腺癌细胞系(A549)的促炎和增殖反应及其与EGFR的关系研究
Subhadip Kundu,Suman Sengupta,Arindam Bhattacharyya
Subhadip Kundu
Exposure to cadmium is associated with the development of pulmonary damage such as emphysema and lung cancer. This metal is also a powerful inducer of different proinflammatory and cell cycle regulatory proteins in many biologic models. Pre...
Yehia Y Hammad,Luis F Pieretti
Yehia Y Hammad
The purpose of this study was to characterize and evaluate the performance of a whole-body human exposure chamber for controlled test atmospheres of gases and particulates. This article is a report on the performance of the system with gas ...
Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone [0.03%]
健康人、变应性非哮喘患者和变应性哮喘患者接触臭氧后的气道嘌呤能反应
Charles R Esther Jr,David B Peden,Neil E Alexis et al.
Charles R Esther Jr et al.
Context: Ozone exposure triggers airway inflammatory responses that may be influenced by biologically active purine metabolites. Objective: ...
The role of iron in Libby amphibole-induced acute lung injury and inflammation [0.03%]
铁离子在利伯石棉尘诱导的急性肺损伤和炎症中的作用研究
Jonathan H Shannahan,Andrew J Ghio,Mette C Schladweiler et al.
Jonathan H Shannahan et al.
Complexation of host iron (Fe) on the surface of inhaled asbestos fibers has been postulated to cause oxidative stress contributing to in vivo pulmonary injury and inflammation. We examined the role of Fe in Libby amphibole (LA; mean length...
Insights from a multi-year program designed to test the impact of ingredients on mainstream cigarette smoke toxicity [0.03%]
一项多年程序的见解：该程序旨在测试主流香烟烟雾毒性的多成分影响
Charles L Gaworski,Karl A Wagner,Michael J Morton et al.
Charles L Gaworski et al.
Context: Cigarette tobacco ingredients may alter the distribution of chemical constituents present in smoke. When considering the toxicological relevance of potential ingredient-related effects on chemical and biological ...
A comprehensive evaluation of the toxicology of cigarette ingredients: inorganic compounds [0.03%]
关于烟叶成分的毒理学综合评估：无机化合物
Christopher R E Coggins,Erica J Sena,Michael J Oldham
Christopher R E Coggins
Context: Two ammonia compounds, diammonium phosphate and ammonium hydroxide, are typically used in the processing or flavoring of tobacco used in the manufacture of cigarettes. ...
A comprehensive evaluation of the toxicology of cigarette ingredients: aromatic carbonyl compounds [0.03%]
烟草成分的毒理学综合评估：芳香族羰基化合物
Christopher R E Coggins,Erica J Sena,Timothy B Langston et al.
Christopher R E Coggins et al.
Context: Aromatic carbonyls are typically used in the processing or flavoring of tobacco used in the manufacture of cigarettes. Objective: ...
Molecular changes in the esophageal epithelium after a subchronic exposure to cigarette smoke in the presence of bile-acid reflux [0.03%]
胆汁酸反流存在下的慢性吸烟暴露对食管上皮分子改变的影响
Harini S Aiyer,Yan Li,Nicholas Harper et al.
Harini S Aiyer et al.
Background: Gastroesophageal reflux of bile acids plays an important role in the development of Barrett's esophagus (BE)-associated esophageal adenocarcinoma (EAC). Cigarette smoke has been demonstrated to exacerbate the ...
The relationship between traffic-related air pollutants and cardiac autonomic function in a panel of healthy adults: a further analysis with existing data [0.03%]
基于现有数据的进一步分析：交通相关空气污染物与健康成年人心脏自主神经功能的关系
Shaowei Wu,Furong Deng,Jie Niu et al.
Shaowei Wu et al.
Context: Epidemiological studies have linked particulate matter (PM) and carbon monoxide (CO) exposures with alterations in cardiac autonomic function as measured by heart rate variability (HRV) in populations. Recently, ...
I S Riddervold,J H Bønløkke,L Mølhave et al.
I S Riddervold et al.
Exposure to wood smoke in the general population is increasing and concurrently, also our awareness. This article describes a wood-smoke generating system for studying human exposure to wood smoke and symptoms related to this exposure. Twen...