Numerical investigation of the effects of respiratory modes and ablation lesions on airflow and particle deposition in a pulmonary acinar model [0.03%]
基于肺泡模型的呼吸模式及射频消融对气流和颗粒沉积影响的数值研究
Qian Tang,Xin Zheng,Jia Lu et al.
Qian Tang et al.
Understanding particle deposition patterns in the pulmonary acinus is essential for early intervention and treatment in acinar diseases. This study numerically investigated the effects of respiratory modes and emphysematous alveolar wall ab...
Evaluation of inhalation and dermal exposure to VOCs and SVOCs from commercial nebulizers in the pediatric population [0.03%]
评估商业雾化器在儿科人群中的挥发性有机化合物和半挥发性有机化合物的吸入和皮肤暴露量
Gabriela Ventura Silva,Miguel P P Filipe,António A Martins et al.
Gabriela Ventura Silva et al.
Objective: Nebulizers are medical devices that convert liquid solutions, such as saline or medication, into aerosols for direct airway delivery. Their effectiveness relies on interfaces, typically made from polymeric mate...
Molecular disruption of pulmonary surfactant proteins by airborne pollutants: an integrative in-silico toxicology approach [0.03%]
基于计算毒理学的空气污染物对肺表面活性物质分子扰动的整合研究
Saba Beigh
Saba Beigh
Objective: Pulmonary surfactant proteins (SP-A, SP-B, SP-C, and SP-D) are essential regulators of alveolar surface tension and pulmonary immune defense, forming a critical frontline barrier against airborne xenobiotics. T...
Identification of diniobium pentaoxide as a novel nuisance dust in a 90-day nose-only inhalation study [0.03%]
五氧化二铌吸入90天鼻导管研究的识别及其作为有害粉尘的影响系数评估
Gustav Gerd Bruer,Paula Janssen,Dirk Schaudien et al.
Gustav Gerd Bruer et al.
Objective: The presence of fine dusts in the industrial working environment has significant implications for occupational safety. As a result, legislators have implemented regulations to protect employees from adverse lun...
Application of a human bronchoepithelial-air-liquid interface model to assess respiratory hazard of VOCs using a benchmark concentration modeling approach [0.03%]
采用基准浓度模型方法评估挥发性有机化合物呼吸危害的体外气液界面模型应用研究
Olivia C G Lampe,Eva C M Vitucci,Carolyn L Cannon et al.
Olivia C G Lampe et al.
Objective: Volatile organic compounds (VOCs) are prevalent in both indoor and outdoor environments and have been linked to health effects. This study aimed to assess VOC-induced effects on the respiratory epithelium using...
M Davigo,F J van Schooten,A Opperhuizen et al.
M Davigo et al.
Introduction: Heated Tobacco Products (HTPs) are marketed as less harmful alternatives than cigarettes. While industry-funded studies suggest lower risks associated with HTP use compared with cigarettes, the health impact...
Introduction to science education and research on vaping and interventions for community engagement [0.03%]
科学教育介绍及关于雾化和社区参与干预的研究
Christa Wright,J Shannahan,S Sharma et al.
Christa Wright et al.
Narrative review: neutrophil activation and NETosis in carbon nanotube-induced lung injury reveal mechanistic insights and biomarker based risk assessment [0.03%]
述评：基于中性粒细胞活化和NETosis的碳纳米管致肺损伤机制见解及生物标志物风险评估
Xinxin Hu,Xiaojun Qian,Jing Wen
Xinxin Hu
Objective: Carbon nanotubes (CNTs) are increasingly applied in industrial and biomedical fields, yet their fiber-like geometry and structural durability raise concerns about inhalation risks in occupational settings. This...
BML-111 mitigates phosgene-induced acute lung injury in rats by activating ACE2 [0.03%]
BML-111通过激活ACE2缓解rats急性肺损伤
Xiaojie Guo,Zi Long,Minjie Shi et al.
Xiaojie Guo et al.
Objective: Phosgene is a highly toxic asphyxiating gas and also an important chemical raw material. Phosgene has been regarded as an environmental pollutant, and the accidental leakage of phosgene in the process of indust...
Hunter A Welch,Whitney L Spaeth,Meiyi Zhang et al.
Hunter A Welch et al.
Objective: Vaping's perception as a safe method of nicotine consumption has contributed to its widespread use among American youth. Research indicates that serious lung disease termed EVALI (E-cigarette or Vaping Product ...