Association of exposure to environmental heavy metals with markers of sepsis susceptibility: a population-based study from NHANES [0.03%]
环境重金属暴露与脓毒症易感标志物相关性的人群研究：来自NHANES的数据
Duo Li,Zhu Yue,Genshen Zhen
Duo Li
Background: Sepsis is a life-threatening syndrome of immune dysregulation; preexisting lymphopenia and an elevated neutrophil-to-lymphocyte ratio (NLR) heighten host susceptibility. Chronic low-dose exposure to lead (Pb),...
Regional and size-dependent effects of ambient agricultural particulate matter on Ah-receptor activity and inflammatory responses in human U937 macrophages [0.03%]
室外农业颗粒物对人单核细胞瘤U937细胞的区域性和尺寸依赖性效应及炎性反应的影响研究
Xiyuan Li,Jiang Chengcheng,Chuanzhen Zhang et al.
Xiyuan Li et al.
Aims: Size-fractionated ambient particulate matter (PM) was collected from two of the most highly PM-polluted agricultural regions in California the Imperial Valley (PMIV), and San Joaquin Valley (Parlier, PMPA), to compa...
Development of alveoli-distributed lung geometry for ferrets to predict particle deposition in the respiratory tract [0.03%]
用于预测呼吸系统粒子沉降的分布有泡肺几何模型的制订——以小狐猴为例
Bahman Asgharian,Owen T Price,Michael J Oldham
Bahman Asgharian
Objective: Ferrets have long served as an important animal model for the study of respiratory infections, inhalation toxicology, and aerosolized therapeutics because of their anatomical and physiological similarities to h...
Concerns about methodology and inference in Davigo and colleagues' review of heated tobacco products [0.03%]
戴维戈及其同事关于加热烟草产品的回顾性研究中的方法学和推理疑虑
Red Thaddeus D Miguel,Isabella Steffensen
Red Thaddeus D Miguel
Acute ozone exposure results in airway epithelial and immune cell disturbances in mice [0.03%]
急性臭氧暴露导致小鼠气道上皮和免疫细胞紊乱
Kshitiz Paudel,Sivapriya Ramamoorthy,Sonika Patial et al.
Kshitiz Paudel et al.
Objective: Elevated levels of ambient ozone (O3), a criteria air pollutant produced by industries and automobiles, are significantly correlated with increased respiratory morbidity. Acute O3 exposure disrupts airway epith...
N-acetylcysteine multifaceted activity in the control of toxicity induced in C57BL/6 mice by long-term inhalation of low-dose formaldehyde [0.03%]
N-乙酰半胱氨酸多效性调节C57BL/6小鼠长期低剂量甲醛吸入所致毒性的机制研究
Elena Cecilia Marcano-Gómez,Pedro Alves Machado-Junior,Ana Beatriz Farias de Souza et al.
Elena Cecilia Marcano-Gómez et al.
Objective: This study investigated whether N-acetylcysteine (NAC) protects against the harmful effects induced by long-term inhalation of low-dose formaldehyde (FA). ...
From laboratory to field: integrating real-world particle size into exposure-relevant agrochemical occupational risk assessment [0.03%]
从实验室到实地：在农药职业风险评估中整合与暴露相关的现实颗粒大小
Alison M Pecquet,Carrie Huffman,Brianna L Jackson et al.
Alison M Pecquet et al.
Objective: Inhalation risk assessments that do not account for human relevant particle size distributions (PSDs) in the inhalation dosimetry adjustment can overestimate risk. This stems from a mismatch between animal toxi...
Hematopoietic carcinogen assessment in bulk chemical products and air samples: focus on benzene exposure among subway maintenance workers [0.03%]
整体化学产品和空气样本的造血致癌物评估：以地铁维修工人的苯接触为重点
Inja Choi,Youngeun Choi,Hye Seung Lee et al.
Inja Choi et al.
Aims: Multiple cases of hematopoietic cancer have been reported among subway maintenance workers (MWs) at a company in Korea employing about 3,400 people, prompting a need to examine the relationship between HC and mainte...
Oleanic acid inhibits LPS-induced inflammation and pyroptosis in pulmonary epithelial cells via mediation of TNFAIP3/NF-κB axis [0.03%]
olean酸通过介导TNFAIP3 / NF-κB轴抑制LPS诱导的肺上皮细胞炎症和pyroptosis
Xianghui Li
Xianghui Li
Background: The progression of sepsis seriously threatens people's life. In addition, acute lung injury can contribute to the injury of epithelial cells. Meanwhile, oleanic acid can inhibit the inflammatory responses in A...
The impact of increased living temperature on the cardiopulmonary response of male and female mice to benzene toluene ethylbenzene and xylene (BTEX) [0.03%]
温度升高对小鼠苯、甲苯、乙苯和二甲苯(BTEX)心血管反应的性别差异的影响机制研究
Sydnie Toler,Michelle F Fyle,Logan Klein et al.
Sydnie Toler et al.
Objective: Benzene, toluene, ethylbenzene, and xylene (BTEX) are ubiquitous pollutants, and leakage of underground storage tanks has increased the risk of inhalation exposure and health effects that are likely impacted by...