Elongated particulate burden in an individual who died of mesothelioma and had an occupational history as a talc "mucker" [0.03%]
一位因间皮瘤死亡且职业履历为滑石“mocker”的个体中的细长颗粒负荷
Ronald F Dodson,Jacqueline Moline,Carlos D Salinas et al.
Ronald F Dodson et al.
Introduction: Tissue from a 77-year-old man diagnosed with mesothelioma was referred with a request for identification of the presence of fibrous structures in tissue samples. The individual's work history including worki...
Evaluation of neural reflex activation as a potential mode of action for respiratory and cardiovascular effects of fine particulate matter [0.03%]
神经反射激活作为细颗粒物引起呼吸和心血管效应潜在作用机制的评估
Robyn L Prueitt,Cassandra J Meakin,Nicholas L Drury et al.
Robyn L Prueitt et al.
Objectives: Mortality from respiratory and cardiovascular health conditions contributes largely to the total mortality that has been associated with exposure to PM2.5 in epidemiology studies. A mode of action (MoA) for th...
Crystalline silica-induced pulmonary inflammation and autoimmunity in mature adult NZBW/f1 mice: age-related sensitivity and impact of omega-3 fatty acid intervention [0.03%]
结晶二氧化硅诱导的成熟成人NZBW / f1小鼠肺部炎症和自身免疫：与年龄有关的敏感性和ω-3脂肪酸干预的影响
Lauren K Heine,Tasha Scarlett,James G Wagner et al.
Lauren K Heine et al.
Objective: Occupational exposure to respirable crystalline silica (cSiO2) has been linked to lupus development. Previous studies in young lupus-prone mice revealed that intranasal cSiO2 exposure triggered autoimmunity, pr...
Biological effects of diesel exhaust inhalation. III cardiovascular function [0.03%]
柴油废气吸入的生物效应。III心血管功能
Kristine Krajnak,Hong Kan,Janet A Thompson et al.
Kristine Krajnak et al.
Objective: Inhalation of diesel exhaust (DE) has been shown to be an occupational hazard in the transportation, mining, and gas and oil industries. DE also contributes to air pollution, and therefore, is a health hazard t...
Short-term hyperoxia induced mitochondrial respiratory chain complexes dysfunction and oxidative stress in lung of rats [0.03%]
短期高氧引起的肺组织线粒体呼吸链复合物功能障碍及氧化应激反应
Leonardo Tenfen,Richard Simon Machado,Khiany Mathias et al.
Leonardo Tenfen et al.
Background: Oxygen therapy is an alternative for many patients with hypoxemia. However, this practice can be dangerous as oxygen is closely associated with the development of oxidative stress. ...
Lipid mediators of inhalation exposure-induced pulmonary toxicity and inflammation [0.03%]
吸入暴露诱导的肺毒性和炎症的脂质介质
Arjun Pitchai,Kimberly Buhman,Jonathan H Shannahan
Arjun Pitchai
Many inhalation exposures induce pulmonary inflammation contributing to disease progression. Inflammatory processes are actively regulated via mediators including bioactive lipids. Bioactive lipids are potent signaling molecules involved in...
Notoginsenoside R1 restrains the proliferation and migration of airway smooth muscle cells isolated from rats with chronic obstructive pulmonary disease [0.03%]
-notoginoside R1抑制来自慢性阻塞性肺疾病大鼠的支气管平滑肌细胞的增殖和迁移
Xiaoyong Li,Kai Chen,Xuefei Shi et al.
Xiaoyong Li et al.
Objective: Chronic obstructive pulmonary disease (COPD) is a common disorder that is characterized by systemic and lung inflammation. Notoginsenoside R1 (NGR1) displays anti-inflammatory properties in numerous diseases. W...
Inhalation exposure to toxic heavy metals in nail salon technicians and health risk assessment using Monte Carlo simulation [0.03%]
美甲技师对有毒重金属的吸入暴露及采用蒙特卡洛模拟的健康风险评估
Zohreh Mohebian,Fatemeh Paridokht,Sara Karimi Zeverdegani et al.
Zohreh Mohebian et al.
Objective: Nail salons offer a developing and diverse occupation for many women, especially the new generation. Due to the increasing apprehension surrounding heavy metals in dust caused by filing nails containing dried n...
Comparison of the effects of active and passive smoking of tobacco cigarettes, electronic nicotine delivery systems and tobacco heating products on the expression and secretion of oxidative stress and inflammatory response markers. A systematic review [0.03%]
烟草卷烟、电子尼古丁递送系统和烟草加热产品主动吸烟和被动吸烟对氧化应激和炎症反应标志物的表达和分泌的影响的比较。系统回顾
Paulina Natalia Kopa-Stojak,Rafal Pawliczak
Paulina Natalia Kopa-Stojak
Objectives: This work attempts to summarize current knowledge on the effects of active and passive smoking of cigarettes, electronic nicotine delivery systems and tobacco heating products on the expression and secretion o...
Inhaled endotoxin induces a systemic neutrophil response without affecting cardiovascular measures in a randomized cross-over exposure study [0.03%]
吸入内毒素诱导全身中性粒细胞反应而在随机交叉暴露研究中不影心血管反应
Stephen A Schworer,Alan L Hinderliter,Melissa C Caughey et al.
Stephen A Schworer et al.
Objective: The gram-negative bacterial cell wall component endotoxin (lipopolysaccharide, LPS) is a key component of particulate matter (PM). PM exposure is associated with cardiovascular morbidity and mortality. However,...
Randomized Controlled Trial
Inhalation toxicology. 2024 Feb;36(2):100-105. DOI:10.1080/08958378.2024.2316241 2024