Exposure to tungsten particles via inhalation triggers early toxicity marker expression in the rat brain [0.03%]
吸入钨颗粒触发大鼠脑早期毒性标志物表达
Léo Macé,Chloé Brizais,Florence Bachelot et al.
Léo Macé et al.
Objective: Our work is focused on tungsten, considered as an emerging contaminant. Its environmental dispersion is partly due to mining and military activities. Exposure scenario can also be occupational, in areas such as...
The effect of enriched versus depleted housing on eucalyptus smoke-induced cardiovascular dysfunction in mice [0.03%]
enrichment和depletion饲养对桉树烟诱导的小鼠心血管功能障碍的影响
Molly E Harmon,Michelle Fiamingo,Sydnie Toler et al.
Molly E Harmon et al.
Objectives: Living conditions play a major role in health and well-being, particularly for the cardiovascular and pulmonary systems. Depleted housing contributes to impairment and development of disease, but how it impacts body resiliency d...
MiR-421 mediates PM2.5-induced endothelial dysfunction via crosstalk between bronchial epithelial and endothelial cells [0.03%]
miR-421通过气道上皮和内皮细胞之间的相互作用介导PM2.5诱导的内皮功能障碍
Yiqing Chen,Mengting Zeng,Jinxin Xie et al.
Yiqing Chen et al.
Objective: PM2.5 is closely linked to vascular endothelial injury and has emerged as a major threat to human health. Our previous research indicated that exposure to PM2.5 induced an increased release of miR-421 from the ...
A mouse model of wildfire smoke-induced health effects: sex differences in acute and sustained effects of inhalation exposures [0.03%]
一种野火烟雾致病效应的鼠标模型:吸入暴露急性及持续影响的性别差异
Mary Buford,Sarah Lacher,Matthew Slattery et al.
Mary Buford et al.
Due to climate change, wildfires have increased in intensity and duration. While wildfires threaten lives directly, the smoke has more far-reaching adverse health impacts. During an extreme 2017 wildfire event, residents of Seeley Lake, Mon...
The role of membrane transporters in the absorption of atrazine following nasal exposure [0.03%]
鼻腔暴露后阿特拉津吸收过程中膜转运蛋白的作用机制研究
Wisam Al Bakri,Maureen D Donovan
Wisam Al Bakri
Objective: The purpose of these studies was to investigate the uptake of atrazine across the nasal mucosa to determine whether direct transport to the brain through the olfactory epithelium is likely to occur. These studi...
Sinomenine attenuates bleomycin-induced pulmonary fibrosis, inflammation, and oxidative stress by inhibiting TLR4/NLRP3/TGFβ signaling [0.03%]
延胡索乙素通过抑制TLR4/NLRP3/TGFβ信号通路减轻博来霉素诱导的肺纤维化、炎症和氧化应激
Yijue Liu,Hong Chen,Yan Wu et al.
Yijue Liu et al.
Objective: The present work concentrated on validating whether sinomenine alleviates bleomycin (BLM)-induced pulmonary fibrosis, inflammation, and oxidative stress. ...
Characterization of mass distribution in a biomimetic aerosol exposure system [0.03%]
仿生气溶胶暴露系统的质量分布特征研究
S Emma Sarles,Edward C Hensel,Caleb Nuss et al.
S Emma Sarles et al.
Objective: Lack of biomimicry in geometry and flow conditions of emissions systems for analytical testing and biological exposure has led to fundamental limitations, including a poor understanding of dose delivered to spe...
Human health impacts attributable to inhalation exposure of particulate matter (PM10 and PM2.5) during the Holi festival [0.03%]
与洒红节期间吸入颗粒物(PM10和PM2.5)暴露相关的健康影响
Abhinandan Khajuria,Pallavi Saxena,Saurabh Sonwani et al.
Abhinandan Khajuria et al.
Objective: The present study focuses on residential areas of Delhi to identify the elevated levels of ambient PM10 and PM2.5 due to biomass burning followed by the coloring activity in the Holi festival celebrated at the ...
Traffic-related air pollution in marginalized neighborhoods: a community perspective [0.03%]
边缘化社区居民视角的交通相关大气污染问题研究
Rahanna N Khan,Antonio F Saporito,Jania Zenon et al.
Rahanna N Khan et al.
Objectives: Marginalized communities are exposed to higher levels of traffic-related air pollution (TRAP) than the general population. TRAP exposure is linked to pulmonary toxicity, neurotoxicity, and cardiovascular toxic...
The presence of erionite in North American geologies and the estimated mesothelioma potency by region [0.03%]
北美地学中菱沸石的存在及其各地区所致间皮瘤的估算毒力
Michael E Stevens,Dennis J Paustenbach,Noah J Lockhart et al.
Michael E Stevens et al.
Objective: Erionite is a naturally occurring fibrous mineral found in soils in some geographical regions. Known for its potency for causing mesothelioma in the Cappadocia region of Turkey, the erionite fiber has attracted...