Co-existing ambient fine particulate matter exacerbated electronic cigarette toxicity on human respiratory cells [0.03%]
共存的环境细颗粒物加剧了电子烟对人类呼吸道细胞的危害
Guanghe Wang,Wenjing Liu,Yujie Cao et al.
Guanghe Wang et al.
Respiratory co-exposure to ambient PM2.5 and electronic cigarettes (e-cigarettes) frequently occurs in public. However, the combined effects on human respiratory health have not been well documented. To discuss potential co-effects and poss...
Bergapten attenuates sepsis-induced acute lung injury in mice by regulating Th17/Treg balance [0.03%]
bergapten通过调节Th17/Treg平衡减轻小鼠脓毒症诱导的急性肺损伤
Shanqiu Shi,Rui Deng,Renchun Huang et al.
Shanqiu Shi et al.
Background: The abnormality of the immune system caused by infection is a contributor to the organ dysfunctions associated with sepsis. The balance between Th17/Treg cells is essential for maintaining immune homeostasis. ...
Impact of soluble epoxide hydrolase inhibition on silica-induced pulmonary fibrosis, ectopic lymphoid neogenesis, and autoantibody production in lupus-prone mice [0.03%]
溶血性磷脂酶D抑制剂PLB268对狼疮易感小鼠硅尘诱导的肺纤维化、淋巴组织新生和自身抗体生成的影响
Olivia F McDonald,James G Wagner,Ryan P Lewandowski et al.
Olivia F McDonald et al.
Objective: Acute intranasal (IN) instillation of lupus-prone NZBWF1 mice with crystalline silica (cSiO2) triggers robust lung inflammation that drives autoimmunity. Prior studies in other preclinical models show that solu...
Gene expression changes in mouse lung induced by subacute inhalation of PM10-rich particulate matter [0.03%]
亚急性吸入PM10富集颗粒物诱导小鼠肺组织基因表达变化
Jong-Uk Lee,Jisu Hong,Eunji Park et al.
Jong-Uk Lee et al.
Introduction: Particulate matter (PM) air pollution is associated with an increased incidence of lung diseases, but the underlying mechanisms have not been fully elucidated. In this study, a mouse model of subacute lung i...
Justina R Creppy,Benoit Delache,Julien Lemaitre et al.
Justina R Creppy et al.
Purpose: Airborne pathogen scan penetrate in human respiratory tract and can cause illness. The use of animal models to predict aerosol deposition and study respiratory disease pathophysiology is therefore important for r...
An introduction to the adverse health impacts of inhaled toxicants in global marginalized communities [0.03%]
关于有毒吸入物对全球弱势社区不利健康影响的介绍
Antonio F Saporito,Judith T Zelikoff
Antonio F Saporito
Development of a risk prediction nomogram for delayed neuropsychiatric sequelae in patients with acute carbon monoxide poisoning [0.03%]
急性一氧化碳中毒患者迟发性脑病风险预测列线图的建立
Ghada N El-Sarnagawy,Fatma M Elgazzar,Mona M Ghonem
Ghada N El-Sarnagawy
Objectives: Delayed neuropsychiatric sequelae (DNS) are critical complications following acute carbon monoxide (CO) poisoning that can substantially affect the patient's life. Identifying high-risk patients for developing...
Evaluation of airborne asbestos concentrations associated with the maintenance of brakes on an industrial overhead crane [0.03%]
与工业龙门吊制动装置维护相关的空气中的石棉浓度评估
Tyler Ferracini,Sarah Brown,Brooke Simmons et al.
Tyler Ferracini et al.
Objectives: To evaluate potential airborne asbestos exposures during brake maintenance and repair activities on a P&H overhead crane, and during subsequent handling of the mechanic's clothing. ...
Bahman Asgharian,Owen Price,Scott Wasdo et al.
Bahman Asgharian et al.
Objective: Cigarette smoking can lead to a host of adverse health effects such as lung and heart disease. Increased lung cancer risk is associated with inhalation of carcinogens present in a puff of smoke. These carcinoge...
Celastrol reduces lung inflammation induced by multiwalled carbon nanotubes in mice via NF-κb-signaling pathway [0.03%]
celastrol通过NF-κB信号途径减少多壁碳纳米管诱导的小鼠肺部炎症
Tao-Lin Qing,Xuan-Yao Jiang,Jin-Feng Li et al.
Tao-Lin Qing et al.
Multiwalled carbon nanotubes (MWCNTs) have numerous applications in the field of carbon nanomaterials. However, the associated toxicity concerns have increased significantly because of their widespread use. The inhalation of MWCNTs can lead...