The Fli1 transcription factor aggravates lipopolysaccharide-induced human pulmonary microvascular endothelial cell dysfunction by regulating CXCL2 promoter [0.03%]
转录因子Fli1通过调控CXCL2启动子加剧脂多糖诱导的人肺微血管内皮细胞功能障碍
Zhou Zheng,Lei Liu,Hao Zhang et al.
Zhou Zheng et al.
Objective: Pulmonary microvascular endothelial cell (PMEC) injury is a hallmark of septic acute lung injury (ALI). Elevation of chemokine C-X-C motif ligand 2 (CXCL2) is associated with inflammatory response in various di...
Correction [0.03%]
改正之法
Published Erratum
Inhalation toxicology. 2025 Jun 15:1. DOI:10.1080/08958378.2025.2514900 2025
Identification of functional roles and therapeutic targets of the STAT pathway in PM2.5-induced allergic rhinitis [0.03%]
PM2.5诱导的过敏性鼻炎中STAT通路的功能角色及治疗靶点识别
ChiHang Zhang,JianShu Guo,Lei Lei et al.
ChiHang Zhang et al.
Background: Increasing evidence suggests that exposure to fine particulate matter (PM2.5) is associated with an elevated risk of respiratory diseases. However, the precise mechanisms by which PM2.5 influences inflammatory...
TMEM175 activity in BK-deficient macrophages maintains lysosomal function and mediates silica-induced inflammatory response in macrophages [0.03%]
TMEM175活性可弥补巨噬细胞中两性霉素B缺陷并维持溶酶体功能以及介导二氧化硅诱导的巨噬细胞炎症反应
Rebekah L Kendall,Britten Postma,Andrij Holian
Rebekah L Kendall
Objective: Lysosomal ion channel function in macrophages contributes to the development of silica-induced inflammation. Recent studies have shown that blocking K+ entry into the lysosome via the BK channel reduces silica-induced damage and ...
Maureen Meister,Xiaojia He,Alexandra Noël et al.
Maureen Meister et al.
Electronic nicotine delivery systems (ENDS) arrived on the U.S. market in 2007 and rapidly grew in popularity as a harm reduction tool for traditional cigarette users. While initially marketed as a healthier alternative to combustible cigar...
The association between smoking profile, leukocyte count, and inflammatory indices in males: a cross-sectional analysis of the TABARI cohort study at enrollment phase [0.03%]
吸烟与白细胞计数及炎症标志物的相关性分析——基于TABARI队列研究基线调查数据的横断面研究
Erfan Ghadirzadeh,Mahmood Moosazadeh,Motahareh Kheradmand et al.
Erfan Ghadirzadeh et al.
Background: Cigarette smoking stands as a prominent contributor to global mortality rates, and its impact spans both immediate and long-term effects on hematological parameters; however, in addition to controversial resul...
Association of Glutathione S-transferase gene polymorphism with coronary artery disease (CAD) in North Indian population (Jammu and Kashmir): evidence from a case-control study and an updated meta-analysis [0.03%]
北印度人（杰姆鲁和克什米尔）中谷胱甘肽S转移酶基因多态性与冠状动脉疾病相关性的病例对照研究及荟萃分析最新证据
Jyotdeep K Raina,Ravi Sharma,Naveen Kumar et al.
Jyotdeep K Raina et al.
Background: Chemicals released during cigarette smoking disrupt the structure, function and physiological capacity of the cardiovascular system. Detoxification of these harmful chemicals is done by Glutathione S-transfera...
The empirical metric of mesothelial carcinogenicity for carbon nanotubes and elongate mineral particles [0.03%]
碳纳米管和纤维状矿物颗粒诱发间皮瘤风险的实证评价指标研究
Andrey A Korchevskiy,Ann G Wylie
Andrey A Korchevskiy
Introduction: Carcinogenic potential of elongate particles depends on many characteristics, with dimensional parameters playing an important role at all stages of disease origination and progression. It is important to de...
Zhaoli Zhang,Lingyun Zhu,Yunji Wang et al.
Zhaoli Zhang et al.
Purpose: Dysfunction of pulmonary microvascular endothelial cells (PMVECs) is an important feature of pulmonary embolism (PE) in sepsis. This study aimed to explore the impact of caspase recruitment domain-containing protein 9 (CARD9) on se...
Shaligram Sharma,Maureen Meister,David Christiani et al.
Shaligram Sharma et al.
While electronic nicotine delivery systems or ENDS are often marketed as a safer alternative to traditional cigarettes, emissions generated during the operation of these devices contain a complex mixture of toxic substances. ENDS emissions ...