A positive pressure system for selective human exposure to gas and particulate mixed atmospheres [0.03%]
一种正压系统，可使人选择性地接触气体和颗粒混合气溶胶环境
Jacob S Griffin,S Thorne Gregory,Thomas E Austin et al.
Jacob S Griffin et al.
Introduction: Exposure to air pollution containing particulates (PM) and gas-phase volatile organic compounds (VOCs), is a leading cause of human morbidity and mortality globally. Devising effective protective public heal...
Effect of single inhalation of hypochlorous acid on the activity of cysteine cathepsins in rat blood plasma [0.03%]
单次吸入次氯酸对大鼠血浆半胱氨酸类组织蛋白酶活性的影响
Bohdan Murashevych,Olha Abraimova,Olha Netronina et al.
Bohdan Murashevych et al.
Objective: Gaseous hypochlorous acid HOCl(g) is a promising agent for continuous complex disinfection of premises, but the toxic effect of its inhalation has been practically not studied. In this study, the effect of inha...
The immunological impact of traffic-related air pollution in an Iraqi population; a prospective cross-sectional study [0.03%]
交通相关空气污染对伊拉克人群免疫学影响的前瞻性横断面研究
Salih A Hama,Dunya H Bapir,Hawbash M Rahim et al.
Salih A Hama et al.
Objective: Iraqi automobiles use some of the poorest quality fuel in the world, characterized by extremely high sulfur content. In this study, we aim to investigate the immunological impact of traffic-related air pollutio...
Caroline de Ocampo,K Michael Pollard,Lisa M F Janssen
Caroline de Ocampo
The mucosal origins hypothesis posits that environmental inhalant exposures, including cigarette smoke (CS) and crystalline silica (c-silica), trigger immune responses in the lung mucosa, an extra-articular site, which precede initiating ev...
Establishing a novel combustion generator system to simulate and study emissions from diverse applications [0.03%]
建立一种新型燃烧发生系统以模拟和研究各种应用的排放
Anand Ranpara,William T Goldsmith,Thomas P Batchelor et al.
Anand Ranpara et al.
Inhalation of emissions from combustion events such as military burn pits and wildland-urban interface fires result in exposures to complex aerosols that may cause adverse health effects. A surrogate combustion generator was created to stud...
Sputum and nasal lavage lung-specific biomarkers in occupational exposure to nanomaterials; a mixed methods systematic review with meta-synthesis and meta-analysis [0.03%]
职业接触纳米材料的痰液和鼻灌洗支气管肺特异性生物标志物：系统综合与荟萃分析混合方法研究
Nafiseh Nasirzadeh,Jamal Biganeh,Erfan Khalatbari et al.
Nafiseh Nasirzadeh et al.
The main route of occupational exposure to nanomaterials is inhalation. Sputum and nasal lavage are the most important biological samples to analyze lung-specific biomarkers in occupational exposure. So, the aim of this study is to conduct ...
Shaligram Sharma,Maureen Meister,Xiaojia He et al.
Shaligram Sharma et al.
The ever-changing popularity of electronic nicotine delivery systems (ENDS) among both youth and adults in the United States has been influential in shaping users' perceptions and behaviors. This behavior driven ENDS usage is described as p...
CREBBP stabilizes GNG3 protein through acetylation, thereby activating the NF-κB pathway and exacerbating airway inflammation in allergic rhinitis [0.03%]
CREBBP通过乙酰化稳定GNG3蛋白，激活NF-κB通路并加重过敏性鼻炎气道炎症
Meng Chen,Zhihui Yuan
Meng Chen
Objective: Allergic rhinitis (AR), an allergen-driven chronic inflammatory disorder of nasal mucosa, is characterized by airway inflammation as its cardinal pathological manifestation. While acetylation is known to regula...
Jennifer Krznarich,Tessa Schumann,James Bjork et al.
Jennifer Krznarich et al.
Objective: The increasing frequency and intensity of wildfires pose significant environmental and public health risks. While existing research has highlighted the effects of wildfire smoke exposure on chronic diseases, th...
Saikosaponin D ameliorates sepsis-induced acute lung injury by maintaining alveolar epithelial barrier integrity and inhibiting ferroptosis via Nrf2/HO-1 pathway [0.03%]
槐果碱D通过Nrf2/HO-1信号通路维持肺泡上皮屏障的完整性并抑制铁死亡从而改善脓毒症诱导的急性肺损伤
Lijie Song,Yanyan Tao,Guoyu Lu et al.
Lijie Song et al.
Background: Saikosaponin D (SSD), a triterpenoid saponin extracted from Bupleurum chinensis, has many pharmacological properties. The goal of our study is to assess the roles and mechanisms of SSD in septic acute lung inj...