Building awareness and harm reduction strategies to address vaping risks [0.03%]
建立意识和危害减少策略以应对气溶胶风险
Shaligram Sharma,Xiaojia He,Maureen Meister et al.
Shaligram Sharma et al.
Electronic nicotine delivery systems (ENDS) have become a growing health concern among both youth and adults. Rise in vaping-associated lung injury underscores the consequences of the ENDS usage under certain conditions. In response, stakeh...
Long-term air pollution exposure and incident cardiovascular disease by multimorbidity status: a national cohort study in China [0.03%]
长期空气污染暴露和多发病状况对心血管疾病的发病率的影响——中国队列研究
Zhaofeng Jin,Ying Luo,Wenzhao Liu et al.
Zhaofeng Jin et al.
Objective: To investigate the associations between long-term exposure to ambient air pollutants and incident cardiovascular disease (CVD) in a high-exposure setting and to evaluate whether multimorbidity affects this rela...
The toxic effects of rapeseed methyl ester and petroleum diesel particulate matter on a BEAS-2B cells [0.03%]
蔊菜甲酯和石油柴油颗粒物的毒性对BEAS-2B细胞的影响
Oskari J Uski,Gregory D Rankin,Maria Friberg et al.
Oskari J Uski et al.
Background: The use of alternative and renewable fuels in the transport sector is growing rapidly due to increasing demand for sustainable energy solutions, however implying an increased risk for human exposure to emissio...
Challenges and complexities in treating ammonia-induced lung injuries: ammonia disrupts cellular membranes and induces severe damage [0.03%]
氨致肺损伤的治疗挑战与复杂性:破坏细胞膜诱导严重损伤
Gregory Rankin,Terese Karlsson,Åsa Gustafsson et al.
Gregory Rankin et al.
Objective: Ammonia (NH3) inhalation is a common occupational exposure, causing injuries similar to acute lung injury (ALI). Medical management is limited to supportive care, as no specific antidotes are currently availabl...
Sex modifies response to ozone and nitrogen dioxide: a controlled human exposure study [0.03%]
性别对臭氧和二氧化氮响应的影响:一项人体暴露实验研究
Jairus C Pulczinski,Ana G Rappold,Robert B Devlin et al.
Jairus C Pulczinski et al.
Background: Ozone (O3) and nitrogen dioxide (NO2) are highly reactive gases associated with all cause-mortality. Epidemiology studies suggest that the risk from O3 and NO2 exposure is modified by sex. O3 is more strongly ...
Genetic ablation of p16 leads to pulmonary remodeling, pro-senescence response, and immune modulation in mice exposed to low-dose, Sub-chronic, environmental tobacco smoke [0.03%]
p16基因消融致小鼠低剂量、亚慢性环境烟草烟雾暴露引起肺重塑、促衰老反应及免疫调控
Thivanka Muthumalage,Irfan Rahman
Thivanka Muthumalage
Objective: Cyclin-dependent kinase inhibitor 2 A, CDKN2A/p16INK4a (p16), is a gene involved in regulating the cell cycle, cellular senescence, and inflammatory responses. The role of p16 in pulmonary immune-inflammatory a...
Efficacy of different oxygen delivery methods in carbon monoxide poisoning: a prospective observational study [0.03%]
不同给氧方法一氧化碳中毒疗效的前瞻性观察研究
Safa Donmez,Alp Sener,Nurullah Ishak Isık et al.
Safa Donmez et al.
Objective: Carbon monoxide (CO) poisoning impairs oxygen transport by forming carboxyhemoglobin (COHb). Normobaric oxygen (NBO) is standard therapy, but its COHb elimination rate is slow. This study compared the effective...
Evaluation of protective effects of tannic acid/iron complex against lung fibrosis induced by bleomycin in rat [0.03%]
评估棓酸铁复合物对雷公藤内酯醇致小鼠肺纤维化的保护作用
Amir Siahpoosh,Narges Atefipour,Paria Javam et al.
Amir Siahpoosh et al.
Objective(s): Pulmonary fibrosis (PF) is a seriousand advancing respiratory condition that arises from various contributing factors. Bleomycin (BLM) is a chemotherapeutic drug known to cause different side effects, includ...
Fuat Karakuş,Burak Kuzu
Fuat Karakuş
Objective: Endosulfan, an organochlorine pesticide, consists of two isomers (α-Endosulfan and β-Endosulfan) and a primary metabolite, Endosulfan sulfate (END-SO4). Due to its pervasive environmental contamination and ha...
Episodic ozone exposure over two weeks alters pulmonary inflammation and gene expression in Long-Evans rats [0.03%]
两周内间歇性臭氧暴露可改变长岛大鼠肺部炎症和基因表达水平
Janice A Dye,Makala M Moore,Helen H Nguyen et al.
Janice A Dye et al.
Objective: Elevated exposure to ozone (O3) may occur episodically over short windows of time. However, laboratory investigations have consistently shown that repeated ozone exposures produce an adaptation response, reduci...