Pulmonary and cardiovascular effects of traffic-related particulate matter: 4-week exposure of rats to roadside and diesel engine exhaust particles [0.03%]
交通相关颗粒物的肺和心血管效应：长期暴露大鼠于路边和柴油发动机排放颗粒物中的影响研究
Miriam E Gerlofs-Nijland,Annike I Totlandsdal,Evren Kilinç et al.
Miriam E Gerlofs-Nijland et al.
Traffic-related particulate matter (PM) may play an important role in the development of adverse health effects, as documented extensively in acute toxicity studies. However, rather little is known about the impacts of prolonged exposure to...
Comparative Study
Inhalation toxicology. 2010 Dec;22(14):1162-73. DOI:10.3109/08958378.2010.531062 2010
A kinetic model for human blood concentrations of gaseous halocarbon fire-extinguishing agents [0.03%]
一种人血中卤代碳氢气体灭火剂浓度的动力学模型
Richard E Lyon,Louise C Speitel
Richard E Lyon
A simple kinetic model for calculating the blood concentration history of humans exposed to time-varying concentrations of gaseous, halocarbon fire-extinguishing agents is described. The kinetic model was developed to extend experimental ph...
Comparative Study
Inhalation toxicology. 2010 Dec;22(14):1151-61. DOI:10.3109/08958378.2010.529623 2010
Airway inflammatory response to diesel exhaust generated at urban cycle running conditions [0.03%]
城市行驶条件下柴油尾气引起的呼吸道炎症反应
Maria Sehlstedt,Annelie F Behndig,Christoffer Boman et al.
Maria Sehlstedt et al.
Context: Diesel exhaust (DE) is an important component in traffic-related air pollution, associated with adverse health effects. DE generated at idling has been demonstrated to induce inflammation in human airways, in ter...
Comparative Study
Inhalation toxicology. 2010 Dec;22(14):1144-50. DOI:10.3109/08958378.2010.529181 2010
Exposure-response effects of inhaled sulfur mustard in a large porcine model: a 6-h study [0.03%]
吸入芥子气的暴露反应效应：大型猪模型6小时研究结果
S J Fairhall,B J A Jugg,R W Read et al.
S J Fairhall et al.
Context: Inhalation of sulfur mustard (HD) vapor can cause life-threatening lung injury for which there is no specific treatment. A reproducible, characterized in vivo model is required to investigate novel therapies targ...
Comparative Study
Inhalation toxicology. 2010 Dec;22(14):1135-43. DOI:10.3109/08958378.2010.527398 2010
Asian dust and titanium dioxide particles-induced inflammation and oxidative DNA damage in C57BL/6 mice [0.03%]
亚洲尘土和二氧化钛颗粒对C57BL/6小鼠引起的炎症和氧化性DNA损伤作用研究
You Jin Hwang,Ye Sul Jeung,Min Hae Seo et al.
You Jin Hwang et al.
Inhaled particulate matter (PM) might influence many adverse health effects in human body, including increased exacerbations of pulmonary and cardiovascular diseases. In this study, we examined the associations between PM and pulmonary adve...
Yumi Umeda,Michiharu Matsumoto,Shigetoshi Aiso et al.
Yumi Umeda et al.
The toxicity and carcinogenicity of 1,2-dichloropropane (DCP) were examined by inhalation exposure of male and female F344 rats to DCP for either 13 wk or 2 years. In the 13-wk study, the DCP concentrations used were 125, 250, 500, 1000, or...
Association of angiotensin-1-converting enzyme gene variations with silicosis predisposition [0.03%]
血管紧张素转换酶基因多态性与硅肺易感性的关联研究
Iraj Mohebbi,Isa Abdi Rad,Morteza Bagheri
Iraj Mohebbi
Interactions between several genes and environmental factors occur in silicosis and other dust-mediated pulmonary fibrosis. It has been suggested that several genes play role in individual susceptibility to silicosis. The aim of this study ...
Application of a new dosimetry program TAOCS to assess transient vapour absorption in the upper airways [0.03%]
新的剂量学程序TAOCS在评估上呼吸道瞬时蒸汽吸收中的应用
Geng Tian,P Worth Longest
Geng Tian
Most previous models of vapour absorption in the respiratory tract have assumed steady state flow fields and steady state diffusion into the airway walls. However, recent studies have shown that transient absorption flux into the walls of t...
Direct measurement of toxicants inhaled by water pipe users in the natural environment using a real-time in situ sampling technique [0.03%]
利用实时原位采样技术直接测量水烟使用者在自然环境中的吸入毒物
M Katurji,N Daher,H Sheheitli et al.
M Katurji et al.
While narghile water pipe smoking has become a global phenomenon, knowledge regarding its toxicant content and delivery, addictive properties, and health consequences is sorely lagging. One challenge in measuring toxicant content of the smo...
Low doses of urban air particles from Buenos Aires promote oxidative stress and apoptosis in mice lungs [0.03%]
布宜诺斯艾利斯的低剂量大气颗粒物促进小鼠肺部氧化应激和细胞凋亡
Susana Martin,Eugenio Fernandez-Alanis,Veronica Delfosse et al.
Susana Martin et al.
Air pollution consists of a wide range of gaseous and particulate pollutants. Exposure to particulate matter (PM) can cause oxidative stress within the lung, which in turn can negatively impact health. The mechanisms by which PM causes oxid...