Different sensitivity in expression of transcription factor mRNAs in congenic mice following exposure to low-level toluene [0.03%]
低浓度苯致转录因子基因表达的同源品系小鼠敏感性差异研究
Hidekazu Fujimaki,Tin-Tin Win-Shwe,Shoji Yamamoto et al.
Hidekazu Fujimaki et al.
To investigate the relationship between sensitivity to toluene exposure and genetic background, male congenic mice, C57BL/10 (H-2(b)) and B10.BR/Sg (H-2(k)) were exposed to 0, 5, and 50 ppm toluene for 6 h per day, 5 days per week for 6 wee...
Comparative Study
Inhalation toxicology. 2010 Sep;22(11):903-9. DOI:10.3109/08958378.2010.494256 2010
Malondialdehyde and superoxide dismutase correlate with FEV(1) in patients with COPD associated with wood smoke exposure and tobacco smoking [0.03%]
多元醇和超氧化物歧化酶与木材烟雾暴露及烟草吸烟相关慢性阻塞性肺疾病的FEV1值有关
Martha Montaño,José Cisneros,Alejandra Ramírez-Venegas et al.
Martha Montaño et al.
Tobacco smoking is the primary risk factor for chronic obstructive pulmonary disease (COPD). However, recent epidemiological studies have established domestic exposure to wood smoke and other biomass fuels as additional important risk facto...
Pentoxifylline inhibits intercellular adhesion molecule-1 (ICAM-1) and lung injury in experimental phosgene-exposure rats [0.03%]
氨磷汀抑制光气致大鼠肺组织细胞间粘附分子-1(ICAM-1)的表达和肺损伤
Xiao-di Zhang,Jun-Feng Hou,Xu-Jun Qin et al.
Xiao-di Zhang et al.
Phosgene inhalation results in acute lung injury (ALI) mostly, pulmonary edema and even acute respiratory distress syndrome, but there is no specific antidote. Inflammatory cells play an important role in the ALI caused by phosgene. Interce...
Comparative Study
Inhalation toxicology. 2010 Sep;22(11):889-95. DOI:10.3109/08958378.2010.493900 2010
Jeanclare Seagrave,Waylon M Weber,Gary R Grotendorst
Jeanclare Seagrave
Context: Sulfur mustard (SM) causes skin blistering and long-term pulmonary dysfunction. Its adverse effects have been studied in battlefield-exposed humans, but lack of knowledge regarding confounding factors makes inter...
Comparative Study
Inhalation toxicology. 2010 Sep;22(11):896-902. DOI:10.3109/08958378.2010.493901 2010
Pre and post-natal exposure to ambient level of air pollution impairs memory of rats: the role of oxidative stress [0.03%]
孕期和围产期暴露于环境空气污染损害大鼠记忆：氧化应激的作用
Ana C T Zanchi,Lucas S Fagundes,Fernando Barbosa Jr et al.
Ana C T Zanchi et al.
The aims of this study were to evaluate whether air pollution during pre-natal and post-natal phases change habituation and short-term discriminative memories and if oxidants are involved in this process. As secondary objectives, it was to ...
Comparative Study
Inhalation toxicology. 2010 Sep;22(11):910-8. DOI:10.3109/08958378.2010.494313 2010
Pulmonary toxicity and extrapulmonary tissue distribution of metals after repeated exposure to different welding fumes [0.03%]
重复接触不同焊接烟尘后金属的肺毒性和肺外组织分布
James M Antonini,Jenny R Roberts,Rebecca S Chapman et al.
James M Antonini et al.
Welders are exposed to fumes with different metal profiles. The goals of this study were to compare lung responses in rats after treatment with chemically different welding fumes and to examine the extrapulmonary fate of metals after deposi...
Long-term pulmonary complications of chemical warfare agent exposure in Iraqi Kurdish civilians [0.03%]
伊拉克库尔德平民接触化学战剂的长期肺部并发症
Mostafa Ghanei,Mostafa Naderi,Ali Morad Kosar et al.
Mostafa Ghanei et al.
The Iraqi government used a range of chemical weapons, including blistering and nerve agents, against Iraqi Kurdish civilians in the 1980s. Few data exist about the long-term respiratory consequences of this exposure. In this study, Kurdish...
Urban particulate matter in Beijing, China, enhances allergen-induced murine lung eosinophilia [0.03%]
中国北京的城市颗粒物增强过敏原诱导的小鼠肺嗜酸性粒细胞增多症
Miao He,Takamichi Ichinose,Seiichi Yoshida et al.
Miao He et al.
It has been reported that ambient particulate matter (PM) in some large cities, such as Beijing, China, causes adverse respiratory health effects. However, there is currently no experimental report on the relationship between bronchial asth...
Effects of exposure of rats to periodic versus continuous hyperoxia on antioxidant potentials and free radical production in relation to ultrastructural changes in myocardial cells [0.03%]
大鼠间歇性或持续暴露于高氧下抗氧化潜力、自由基产生及心肌细胞亚细胞结构变化的关系研究
Al-Said A Haffor,Omar S Alttas
Al-Said A Haffor
The purpose of the present study was to examine the effects of periodic hyperoxia training (PHT) and/or continuous exposure to hyperoxia (HP) on free radical (FR) levels and biological antioxidant potentials (BAPs) in relation to ultrastruc...
SO2 inhalation modulates the expression of apoptosis-related genes in rat hippocampus via its derivatives in vivo [0.03%]
二氧化硫通过其衍生物质对大鼠海马细胞凋亡相关基因表达的调控作用
Yang Yun,Hongyan Li,Guangke Li et al.
Yang Yun et al.
The possible neurotoxicity of SO(2) has been implicated by determining morphological change, oxidative stress, DNA damage and membrane channel alteration in previous studies, however, its detailed mechanisms remain unclear. In the present s...
Comparative Study
Inhalation toxicology. 2010 Sep;22(11):919-29. DOI:10.3109/08958378.2010.494694 2010