Tatsuya Corlett,Harrison B Smith,Eric Smith et al.
Tatsuya Corlett et al.
Whereas phylogenetic reconstructions are a primary record of protein evolution, it is unknown whether the deep history of enzymes is encoded at higher levels of biological organization. Here, we demonstrate that the emergence and reuse hist...
US schools' proximity to environmental hazard sites: A national analysis [0.03%]
美国学校与环境隐患地点的接近程度：一项全国性分析
Sohil Malik,Matthew A Kraft,Grace T Falken
Sohil Malik
We conduct a nationwide assessment of U.S. PreK-12 public and private schools' proximity to known environmental hazard sites tracked by the U.S. Environmental Protection Agency: Superfund sites, brownfields, and Toxics Release Inventory fac...
PTPN1 and PTPN2 cooperatively set interferon responsiveness thresholds that govern cancer immune evasion [0.03%]
PTPN1和PTPN2共同调节干扰素反应阈值以调控癌细胞免疫逃逸
Alexandre J Poirier,Chu-Han Feng,Erika Walback et al.
Alexandre J Poirier et al.
Immune evasion by cancer cells remains a major barrier to the success of immune checkpoint blockade (ICB). In recent years, Protein tyrosine phosphatase non-receptor type 2 (PTPN2) has emerged as a promising and druggable target for cancer ...
Genomic signatures of dairy adaptation in Saccharomyces cerevisiae from traditional Yaghnob goat-cheese fermentation [0.03%]
天山萨奇氏酵母适应乳制品发酵的基因组标志物
Marina Bambi,Ahmed El Goutbi,Monica Di Paola et al.
Marina Bambi et al.
The growing interest in studying Saccharomyces cerevisiae strains from previously unexplored niches is greatly expanding our understanding of this yeast's ecology and evolution. While strains involved in alcoholic fermentation are the most ...
Le Yao,Thomas J Algeo,Qiulai Wang et al.
Le Yao et al.
Deep-time hyperthermal/transient warming events provide critical analogs for modern climatic warming and its impacts. However, all ancient hyperthermals documented to date have occurred under greenhouse climate states, limiting their releva...
Le Yao,Thomas J Algeo,Qiulai Wang et al.
Le Yao et al.
Deep-time hyperthermal/transient warming events provide critical analogs for modern climatic warming and its impacts. However, all ancient hyperthermals documented to date have occurred under greenhouse climate states, limiting their releva...
White-matter functional connectivity uniquely predicts brain age, cognition, and psychopathology beyond gray-matter connectivity [0.03%]
白质功能连接在灰质功能连接基础上预测脑老化、认知和精神病理学
Jing Cong,Shaoling Zhao,Haoshu Xu et al.
Jing Cong et al.
White-matter pathways form the structural backbone for communication across the human connectome, yet whether functional connectivity (FC) involving white matter carries information beyond gray-matter networks remains unclear. Here, we test...
Timothy J Mitchison
Timothy J Mitchison