Evaluation of the AnTat A/B and LiTat A/B primers for the detection of Trypanosoma brucei gambiense [0.03%]
AnTat A/B和LiTat A/B引物在检测Trypanosoma brucei gambiense中的应用评估
Hamidou Ilboudo,Martial Kassi NDjetchi,Windingoudi Justin Kaboré et al.
Hamidou Ilboudo et al.
Elimination of gambiense human African trypanosomiasis (gHAT) as a public health problem has been reached or is in sight in a number of endemic foci and the next step is now to reach the elimination of transmission. The ability to detect Tr...
A STEP FORWARD TO REVOLUTIONIZE THE EIMERIOSIS CONTROLLING STRATEGIES IN CATTLE BY USING TRADITIONAL MEDICATION [0.03%]
利用传统药物在控制牛球虫病策略上的革命性进展步骤
Muhammad Zahid Sarfaraz,Sidra Abbas,Muhammad Arfan Zaman et al.
Muhammad Zahid Sarfaraz et al.
More than 10 species of Eimeria is found in cattle but Eimeria zuernii is one of the most pathogenic protozoan parasites affecting the global livestock industry. At the herd level, E. zuernii can cause illness in 10 to 80% of animals and re...
Structural and Functional Implications of MIT2 and NT2 Mutations in Amodiaquine and Piperaquine Resistant Plasmodium berghei Parasites [0.03%]
氨喹和哌喹抗性伯氏疟原虫中MIT2和NT2基因突变的结构与功能影响
Brenda Muriithi,Jean Chepngetich,Beatrice Gachie et al.
Brenda Muriithi et al.
Long-acting drugs, amodiaquine (AQ), lumefantrine (LM), and piperaquine (PQ), are vital components of artemisinin-based combination therapies (ACTs) for malaria treatment. However, the emergence of partial artemisinin-resistant parasites po...
Imidazolium Salt as Potent Amoebicide for Rapid Inactivation of Acanthamoeba spp. Trophozoites and Cysts [0.03%]
咪唑盐作为一种能够快速灭活棘阿米巴虫滋养体和包囊的高效 amoebicide药物
Denise Leal Dos Santos,Beni Jequicene Mussengue Chaúque,Francisco Kercher Berté et al.
Denise Leal Dos Santos et al.
Acanthamoeba spp. are amphizoic protozoa capable of causing several severe diseases in humans and other animals, including granulomatous amoebic encephalitis and Acanthamoeba keratitis (AK). The high resistance of Acanthamoeba genus, especi...
Structural insights into Trichuris muris eggs through 3D modeling, Cryo-SEM, and TEM of samples prepared with HPF-FS [0.03%]
通过3D建模、冷冻扫描电镜和HPF-FS制样的透射电镜对小鼠毛首鞭形线虫虫卵的结构研究
Brunna Vianna Braga,Ludmila Rocha Lima,Larissa Figueiredo Belem et al.
Brunna Vianna Braga et al.
Trichuriasis - a disease caused by Trichuris trichiura - affects underserved communities. Infection occurs by the ingestion of embryonated eggs, a resilient structure against environmental fluctuations - an essential feature for the surviva...
Comparative larvicidal, pupicidal, adulticidal activity of Artemisia nilagirica (C.B. Cl) Pamp extract in controlling Culex quinquefasciatus, Anopheles stephensi, Aedes aegypti and Aedes albopictus [0.03%]
艾纳康那蒿提取物对几种蚊虫的杀幼虫、羽化抑制和成蚊作用研究
Panda Sagorika,Sahoo Rajasri,Sahoo Santi Lata et al.
Panda Sagorika et al.
Vector-borne diseases cause increase in burden, poverty, social liability and death all over the world. Mosquitoes serve as the vector for malaria, dengue, filariasis, yellow fever and also play a major role in transmission of chikungunya a...
Synthetic peptides derived from hypothetical proteins as potential antigens for the diagnosis of canine visceral leishmaniasis and tegumentary leishmaniasis [0.03%]
源自理论蛋白质的合成肽作为犬内脏利什曼病和皮肤利什曼病诊断抗原的潜力研究
Larissa Chaves Freire,Scarleth Silva Costa,Ana Luiza Filizzola Tedeschi et al.
Larissa Chaves Freire et al.
In the present study, we investigated the potential use of five linear peptides as a potential antigens for the immunodiagnosis of tegumentary leishmaniasis (TL) and canine visceral leishmaniasis (CVL). We used bioinformatics approaches to ...
Study of antiplasmodial activity, toxicity, pharmacokinetic profiles of n-methyl-isatin (CH3ISACN) derivative [0.03%]
关于N-甲基异咯津(CH3ISACN)衍生物抗疟活性、毒性及药代动力学特性的研究
Cinthia Rodrigues Melo,Caliandra Maria Bezerra Luna Lima,Brenna Marceliane de Melo Marcelino et al.
Cinthia Rodrigues Melo et al.
One of the main factors that have made it difficult to control malaria is the large number of parasites that are resistant to the usual antimalarial drugs. Therefore, the development of new drugs that are more effective and with low toxicit...
In vitro and in vivo leishmanicidal and trypanocidal activities of isoflavans from Tabebuia chrysantha (Jacq.) G. Nicholson timber by-products [0.03%]
Tabebuia chrysantha (Jacq.) G. Nicholson木材副产品中异黄烷的体内外抗利什曼病和抗锥虫活性
Edwin Correa,Sara M Robledo,Fernando Echeverri et al.
Edwin Correa et al.
Cutaneous Leishmaniasis and Chagas disease are neglected tropical diseases that affect millions worldwide. Despite the high morbidity associated with these infections, current treatments are often highly toxic and are showing diminishing ef...
Antileishmanial activity of Hesperetin on Leishmania donovani, in vitro and in silico inhibition of acetylcholinesterase and investigation of the targets sterol C-24 reductase and N-myristoyltransferase [0.03%]
芸香素抗利什曼病活性的体内和体外研究及其对乙酰胆碱酯酶的抑制作用及胆固醇C-24还原酶和N-我的酰转移酶靶点的研究
Saiaka Ingrid Parente Rocha,Victor Borges Fernandes,Wildson Max Barbosa da Silva et al.
Saiaka Ingrid Parente Rocha et al.
The current treatment of leishmaniasis is confronted with significant challenges, including limited efficacy, adverse effects, and parasite resistance to drugs. The search for alternative therapeutic options, including the utilization of na...