Circulating microRNA profiles as diagnostic and prognostic biomarkers for acute and carrier Theileria equi infection [0.03%]
Marwa M Attia,Hend I Mohamed
Marwa M Attia
Equine piroplasmosis caused by Theileria equi exhibits a wide clinical spectrum ranging from acute disease to lifelong asymptomatic carriage, posing significant diagnostic and epidemiological challenges. In this cross-sectional case-control...
De-centering the drug: Violet light and amphotericin B enhance antileishmanial activity through additive and host-directed effects [0.03%]
去中心化药物：紫光和两性霉素B通过累加作用和宿主导向效应增强抗利什曼病活性
Bruno Pereira Diniz,Cecília Luiza Pereira,Tahira Souza Melo et al.
Bruno Pereira Diniz et al.
Cutaneous leishmaniasis (CL) is a neglected tropical disease associated with significant toxicity of current treatments, high costs, and emerging parasite resistance, highlighting the need for alternative therapeutic strategies. In this con...
Identification, selection and testing of new antigens for tegumentary Leishmaniasis serological diagnosis [0.03%]
identification, selection and detection of新型抗原用于内脏利什曼病的血清学诊断
Bruna Rodrigues de Almeida,Jordanna Luiza de Lima Celeste,Fátima Riberio-Dias et al.
Bruna Rodrigues de Almeida et al.
Tegumentary Leishmaniasis (TL), caused by several Leishmania species, presents a broad spectrum of clinical manifestations. This diversity complicates early and accurate diagnosis, which is crucial for effective treatment a preventing chron...
Comprehensive molecular characterization of Theileria equi: Detection, genetic diversity, and risk factors assessment [0.03%]
泰勒焦虫的综合分子特征分析：检测、遗传多样性及风险因素评估
Biswa Ranjan Maharana,Anita Ganguly,Rashmi Malik et al.
Biswa Ranjan Maharana et al.
Equine piroplasmosis, caused by Theileria equi, has been widely studied globally, but genetic diversity research in India remains limited. Analysis of 306 horse blood samples revealed T. equi infection in 10.78% by microscopy and 21.24% by ...
Combination treatment of topical nystatin and systemic meglumine antimoniate in the BALB/c - Leishmania(Leishmania) amazonensis model [0.03%]
BALB/c小鼠巴西利什曼病模型中制霉菌素联合马糖酸锑的治疗作用研究
Marcella Silva-Figueiredo,Luzia Monteiro Castro Côrtes,Geovane Dias-Lopes et al.
Marcella Silva-Figueiredo et al.
Treating leishmaniasis remains challenging. This study provides evidence of the beneficial effect of combining two clinically approved drugs, topical nystatin and systemic meglumine antimoniate, in an experimental model of cutaneous leishma...
Metal-metronidazole derivatives as potential antitrichomonal agents on Trichomonas vaginalis [0.03%]
金属-甲硝唑衍生物作为解体阴道毛滴虫的潜在抗滴虫剂
Rosilaine Silva de Oliveira,Arquimedes Karam,Chris Hj Franco et al.
Rosilaine Silva de Oliveira et al.
Metronidazole (MTZ) remains the main treatment for Trichomonas vaginalis infections; however, increasing resistance has driven the search for more effective therapeutic alternatives. In this study, we prepared and characterized three metal-...
Climate Change and Vector Ecology: A Comprehensive Review of Environmental Drivers of Insect-Borne Disease Dynamics and Public Health Implications [0.03%]
气候变化与媒介生态学——环境驱动因素对昆虫传染病动力学及公共卫生的影响综述
Ebrahim Abbasi
Ebrahim Abbasi
Background: Climate change significantly affects vector-borne diseases (VBDs) by altering vector ecology, transmission dynamics, and disease geographic spread. Understanding these interactions is crucial for effective pub...
Trans-stadial midgut development in Aedes aegypti L. (Diptera: Culicidae) is long-term impaired by sublethal concentrations of Schinus terebinthifolia Raddi (Anacardiaceae) leaf preparations [0.03%]
Schinus terebinthifolia朱果冬青对埃及伊蚊幼虫期和蛹期的跨阶段肠道发育有长期影响
João Ricardo Sá Leitão Camaroti,Livia Lais de Santana Silva,Thiago Lucas da Silva Lira et al.
João Ricardo Sá Leitão Camaroti et al.
Control of the vector Aedes aegypti L. is the main prophylactic measure for limiting the spread of dengue fever, chikungunya, and Zika virus diseases. In light of the environmental toxicity and resistance development associated with synthet...
Effect of promethazine and hydroxyzine, two inhibitors of Tumor Controlled Translational Protein (TCTP), on the growth of in vitro culture of Trypanosoma brucei gambiense and Trypanosoma congolense [0.03%]
两种肿瘤控制性翻译蛋白(TCTP)抑制剂-扑尔敏和羟嗪对培养基中恶性锥虫(GHPR)和刚果锥虫(Congolese)生长的影响研究
Géraldine Bossard,Anne Geiger
Géraldine Bossard
TCTP, an ubiquitous protein excreted by trypanosomes when cultured in vitro, has also been identified in the intestine of the tsetse fly and in the blood of infected mammalian hosts. Recombinant TCTP was able to modulate the growth of tsets...
PREVALENCE OF INTESTINAL PARASITES IN A TERTIARY CARE HOSPITAL AND UTILITY OF AI-ASSISTED FECAL ANALYZER FOR THEIR DETECTION [0.03%]
印度一家三级医院肠道寄生虫的流行率及其检测的AI辅助粪便分析仪的价值评估
Prabhav Aggarwal,Jyoti Choudhary,Pallavi et al.
Prabhav Aggarwal et al.
Introduction: Intestinal parasitic infections, caused by protozoa and helminths, can lead to malnutrition, anaemia, and impaired growth. While direct wet mount microscopy is the routine diagnostic method, it is limited by...