RvD1 signaling in peripheral macrophages promotes systemic β-amyloid clearance to mitigate the progression of perioperative neurocognitive disorders in mice [0.03%]
外周巨噬细胞中RvD1信号促进系统性β淀粉样蛋白清除以缓解小鼠术后神经认知障碍进展
Yi Ding,Guang-Yuan Xing,Zhen-Yun Mao et al.
Yi Ding et al.
Background: Impaired clearance of beta-amyloid (Aβ) is considered a critical factor contributing to the development of perioperative neurocognitive disorders (PND). Peripheral Aβ clearance has shown promise in reducing ...
Corrigendum to "Urolithin A improves Parkinson's disease-associated cognitive impairment through modulation of neuroinflammation and neuroplasticity" [Experiment neurology, 2025 Nov:393:115395, Manuscript ID during submission is EXNR-25-789, The proof reference is YEXNR_115395] [0.03%]
关于“尿石素A通过调节神经炎症和神经可塑性改善帕金森病相关的认知障碍”的勘误(实验神经学,2025年11月,393:115395,在投稿期间的手稿编号为EXNR-25-789,校对参考号为YEXNR_115395)
Ning Xu,Chenchen Du,Yuan Yu et al.
Ning Xu et al.
Published Erratum
Experimental neurology. 2025 Oct 10:115484. DOI:10.1016/j.expneurol.2025.115484 2025
Exploring the role of CD147 in cerebrovascular and Alzheimer's pathologies: Insights into mechanisms and interventions [0.03%]
CD147在脑血管和阿尔茨海默病病理中的作用探索:机制与干预措施的启示
Patcharapong Pantiya,Nipon Chattipakorn,Siriporn C Chattipakorn
Patcharapong Pantiya
Cluster of Differentiation 147 (CD147), a multifunctional transmembrane glycoprotein, has been identified as a key regulator in the pathophysiology of cerebrovascular diseases and Alzheimer's disease (AD). In cerebrovascular conditions, CD1...
Optimizing L-DOPA treatment through treadmill controlled exercise in a hemi-parkinsonian rat model [0.03%]
通过跑步机控制运动优化左旋多巴治疗半边帕金森病大鼠模型的效果
Shruti Venkatesh,NSenga Kinzonzi,Ashley Galfano et al.
Shruti Venkatesh et al.
Parkinson's Disease (PD) is a movement disorder characterized by the loss of nigrostriatal dopamine (DA) neurons. Early-stage PD motor symptoms are typically controlled with the DA replacement therapy, levodopa (L-DOPA). However, chronic us...
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice [0.03%]
运动引起的mTBI后的分子调节:雄性小鼠的多组学研究
Tseitlin Liron,Metsada Pasmanik-Chor,Chaim G Pick
Tseitlin Liron
Mild traumatic brain injury (mTBI) poses a significant clinical challenge, often resulting in persistent cognitive and neurological impairments. This study investigates the therapeutic effects of a 17-day running protocol on mTBI recovery i...
Elastin-like polypeptide delivery of an NF-kB inhibitor for treatment of juvenile mild TBI complicated by high-fat diet consumption [0.03%]
弹性蛋白多肽递送NF-кB抑制剂治疗高脂饮食引起的青少年轻度TBI并发症
Jacob P Haskell,Allie M Smith,Ian G McGee et al.
Jacob P Haskell et al.
Juveniles are at increased risk for mild traumatic brain injury (mTBI) due to recreational activities, domestic violence, and vulnerabilities of the developing skull. In industrialized nations, adolescents often consume high-sugar, high-fat...
ILF3 downregulation by circMETTL9: Effect on traumatic brain injury-induced neuroinflammation [0.03%]
circMETTL9通过下调ILF3对创伤性脑损伤诱导的神经炎症的影响
Lulu Sun,Hao Huang,Yonglin Hu et al.
Lulu Sun et al.
Neuroinflammation is a pivotal component of the cascade of reactions that follow traumatic brain injury (TBI). Our previous reports have identified circular RNA METTL9 (circMETTL9) as a modulator of neuroinflammation following TBI. Further,...
Experimental and computational study of 40 Hz low-field magnetic stimulation modulating neural activity and pathology in a mouse model of Alzheimer's disease [0.03%]
实验和计算研究:40赫兹低磁场磁刺激调节阿尔茨海默病小鼠模型中神经活动和病理的作用
Duyan Geng,Yuxin Yan,Aoge Liu et al.
Duyan Geng et al.
Background: Low-field magnetic stimulation (LFMS) is a non-invasive, subthreshold neuromodulation technique that has demonstrated rapid mood-enhancing effects in depression. Given that depression often presents as an earl...
MYT1L promotes autophagy to ameliorate amyloid-β pathology and cognitive deficits in Alzheimer's disease via Notch signaling pathway [0.03%]
MYT1L通过诺斯克信号通路促进自噬以缓解阿尔茨海默病患者的淀粉样蛋白-β病理改变和认知缺陷
Meiyan Zhang,Shuangshuang Hai,Xiaoyan Gao et al.
Meiyan Zhang et al.
Autophagy is essential in the growth and advancement of Alzheimer's disease (AD). Myelin transcription factor 1-like (MYT1L) has been reported to have neuroprotective properties; however, its precise role in AD is still unclear. This study ...
Physical exercise protects neurons from energy deficit and improves cognitive function by upregulating astrocytic Slc2a1 in Alzheimer's disease [0.03%]
运动通过上调星形胶质细胞Slc2a1保护神经元免于能量缺失并改善阿尔茨海默病中的认知功能
Shiyin Li,Fang Zheng,Shuhua Liu et al.
Shiyin Li et al.
Alzheimer's disease (AD) has been associated with impaired energy metabolism and neuronal mitochondrial dysfunction, which contribute to the development of anxiety-like behaviors and spatial memory deficits. Astrocytes are recognized as a c...