Medication Targeting to Subcellular Organelles: Emphasizing Mitochondria as a Therapeutic Marvel-Current Situation and Future Prospects [0.03%]
靶向亚细胞器的药物递送：以线粒体为例——现状与未来展望
Riyad F Alzhrani,Adel Ali Alhowyan,Ehab I Taha et al.
Riyad F Alzhrani et al.
Subcellular disorders are linked with several diseases, specifically mitochondrial dysfunction linked to age, metabolic disorders, cancer, cardiovascular disease, and other mitochondrial diseases (MDs). Intracellular medication delivery is ...
PKR Inhibition Reduces High Glucose and H2O2-Induced Injury in Rat Renal Epithelial Cells by Suppressing the Sonic Hedgehog Pathway [0.03%]
PKR抑制通过抑制 sonic hedgehog 途径减少高糖和H２O２诱导的大鼠肾小管上皮细胞损伤
Ganesh Panditrao Lahane,Dishank Aorandekar,Audesh Bhat et al.
Ganesh Panditrao Lahane et al.
Double-stranded RNA-dependent protein kinase (PKR) is involved in signaling pathways that mediate responses to oxidative and endoplasmic reticulum (ER) stress and has been linked to various cardiovascular diseases. However, the role of PKR ...
CLEC5A suppresses cell growth and metastasis via interfering with the calcineurin/NFATc1 signaling pathway in osteosarcoma [0.03%]
CLEC5A通过干扰骨肉瘤中的钙神经蛋白/NFATc1信号通路抑制细胞生长和转移
Bin Hu,Ruifeng Shi,Xiang-An Kong et al.
Bin Hu et al.
Osteosarcoma (OS) is a prevalent primary bone malignancy characterized by a poor prognosis due to its high metastatic potential. Although the dysregulation of C-type lectin domain family 5, member A (CLEC5A) has been reported in various can...
Tissue Is the Issue: Overcoming Tissue Limitations in Lung Cancer Through Cryobiopsy and the Application of Lung Cancer Organoids and Lung Cancer-on-a-Chip in Precision Medicine [0.03%]
组织是问题的关键：通过冷冻活检和肺癌类器官及芯片技术在精准医学中克服肺癌组织限制的问题
Yoonjoo Kim,Dongil Park,Dahye Lee et al.
Yoonjoo Kim et al.
Estradiol inhibits endometrial injury by promoting the stability of the KLF15 protein and the recovery of mitochondrial function [0.03%]
雌二醇通过促进KLF15蛋白稳定性及线粒体功能恢复抑制子宫内膜损伤
Jianghong Zhou,Zhenghua Xiong,Xicui Long et al.
Jianghong Zhou et al.
Background: Endometrial injury (EI) is an important factor leading to infertility, which seriously affects women's fertility and reproductive health. Research indicates that estradiol (E2) therapy can promote the repair o...
LncRNA USP2-AS1 Facilitates Colorectal Cancer Development Through The PHLDA2/PI3K/AKT Axis [0.03%]
长链非编码RNA USP2-AS1通过PHLDA2/PI3K/AKT轴促进结直肠癌发生发展
Jing Zhu,Shuhui Lin,Lisha Chang et al.
Jing Zhu et al.
Colorectal cancer (CRC) is one of the most common malignant tumors worldwide, seriously threatening human health. Researchers have revealed that long non-coding RNAs (lncRNAs) are involved in the development of multiple cancers, including C...
Retraction notice to "DDX18 influences chemotherapy sensitivity in colorectal cancer by regulating genomic stability" [Exp. Cell Res. 444 (2025) 114344] [0.03%]
撤销通知《DDX18通过调节基因组稳定性影响结直肠癌化疗敏感性》[实验细胞研究，444 (2025) 114344]
Wenchao Zhao,Qingqing Luo,Han Zhan et al.
Wenchao Zhao et al.
Retraction notice to "Silenced long non-coding RNA activated by DNA damage elevates microRNA-495-3p to suppress atherosclerotic plaque formation via reducing Krüppel-like factor 5" [Exp. Cell Res. 401 (2021) 112519] [0.03%]
撤稿通知：“由DNA损伤激活的长非编码RNA通过降低Krüppel样转录因子5来抑制动脉粥样硬化斑块形成及提高microRNA-495-3p水平”[《实验细胞研究》401 (2021) 112519]
Dan-Ni Fu,Yu Wang,Li-Jun Yu et al.
Dan-Ni Fu et al.
EZH2 in Digestive System Cancers: Epigenetic Regulation, Oncogenic Interactions, and Therapeutic Potential [0.03%]
EZH2在消化系统癌症中的表观遗传调控、致癌互作及治疗潜力
Ahmed Hjazi,Ahmed Hussn,A K Kareem et al.
Ahmed Hjazi et al.
EZH2 (enhancer of zeste homolog 2) is an important component of the Polycomb Repressive Complex 2 (PRC2) and is essential for the epigenetic regulation of gene expression. EZH2 primarily methylates histone H3 at lysine 27 (H3K27me3) to repr...
Pan-carcinoma data driven analysis reveals Platelet-Activating Factor Receptor (PTAFR) involvement in immunosuppressive tumor microenvironment signaling and clinical prognosis [0.03%]
泛癌谱系数据分析揭示了血小板活化因子受体（PTAFR）在免疫抑制性肿瘤微环境信号传导及临床预后中的作用
Barbara Dalmaso,Ildefonso Alves da Silva-Junior,Sonia Jancar et al.
Barbara Dalmaso et al.
Solid tumor carcinogenesis is driven by complex interactions within the tumor microenvironment (TME), which influence tumor initiation, progression, and response to treatment. The phospholipid platelet-activating factor (PAF) has been descr...