Fibrinogen regulates microglial function through the JAK2/STAT3 signaling pathway [0.03%]
纤维蛋白原通过JAK2/STAT3信号通路调节小胶质细胞功能
Xiaohui Li,Xiujuan Song,Fei Yi et al.
Xiaohui Li et al.
Background: Neuroinflammation, a defining feature of numerous neurological disorders, arises predominantly from activating immune cells such as microglia, which play a critical role in maintaining homeostasis within the c...
Retraction notice to "Protective efficacy of a plasmid DNA vaccine against transgene-specific tumors by Th1 cellular immune responses after intradermal injection" [Cell. Immunol. 329 (2018) 17-26] [0.03%]
有关于“通过皮下注射针对转基因特异性肿瘤的DNA疫苗的保护效力”一文([Cell. Immunol. 329 (2018) 17-26])的撤稿声明
Hye-Youn Son,Vasso Apostolopoulos,June-Key Chung et al.
Hye-Youn Son et al.
Integrated proteomics and phosphoproteomics profiling dynamic signaling networks underlying two distinct types of macrophage activation [0.03%]
整合蛋白质组和磷酸化蛋白质组鉴定两种不同类型巨噬细胞激活的动态信号网络
Lihong Wu,Hang Xu,Xiaonan Zhang et al.
Lihong Wu et al.
Macrophages play a crucial role in antimicrobial host defense and those with differential maturation/differentiation status differ in inflammatory responses. Herein, GM-CSF and M-CSF primed mouse bone marrow derived macrophages (GM-BMDMs, G...
METTL3 facilitates osteoblast differentiation and bone regeneration via m6A-dependent maturation of pri-miR-324-5p [0.03%]
METTL3通过m6A依赖的pri-miR-324-5p成熟促进成骨细胞分化和骨再生
Jing Xiao,Zhiyuan Xu,Zhiwei Deng et al.
Jing Xiao et al.
Background: Osteoblast differentiation is essential for fracture healing and bone regeneration. miR-324-5p has been implicated in osteoporosis, but its precise role in osteogenic differentiation remains unclear. We invest...
Investigating the effect of neuro-immune communication on immune responses in health and disease: Exploring immunological disorders [0.03%]
探究神经免疫通讯对健康和疾病中免疫反应的影响：探索免疫障碍
Fatemeh Hesampour,Charles N Bernstein,Jean-Eric Ghia
Fatemeh Hesampour
Recent recognition of the intricate nervous-immune system interplay has prompted research into the specific cellular components involved in these interactions. Emerging evidence suggests that immune and neural cells collaborate within disti...
Apelin-13 enhances neurofunctional recovery and suppresses neuroinflammation via the SIRT1/NF-κB axis in ischemic stroke [0.03%]
阿皮林-13通过SIRT1/NF-κB轴增强缺血性卒中的神经功能恢复并抑制神经炎症反应
Zhe Peng,Dewen Ru,Guangpeng Leng et al.
Zhe Peng et al.
Background: Ischemic stroke is a major cause of mortality and disability, with neuroinflammation driving secondary brain injury. Microglial activation contributes to neuronal apoptosis, BBB disruption, and prolonged neuro...
Progress of exosomes in regulating tumor metastasis by remodeling the pre-metastatic immune microenvironment [0.03%]
外泌体调控肿瘤转移微环境免疫细胞重塑的研究进展
Jiangning Xiang,Lin Yao,Shan Wang et al.
Jiangning Xiang et al.
Exosomes play an important role in the metastatic microenvironment, acting as a transmission belt that facilitates intercellular communication. By delivering proteins, nucleic acids, and other substances in the exosomes, they can change the...
Characterization of lysate from NK-92 cells and its potential use as an immunotherapeutic modality [0.03%]
NK-92细胞裂解物的特征分析及其作为免疫治疗手段的潜在应用价值
Himani Chinnapen,Laurent Boissel,Courtney Fleenor et al.
Himani Chinnapen et al.
Lysates from human cells represent biofluids that are used in the biotechnology field for a number of reasons such as biomarker identification and antibody detection. Lysate from human blood platelets is widely used in the clinical setting ...
Modular activation of macrophage-like cells by beta-2-microglobulin via mitochondria and the cGAS-STING pathway [0.03%]
β2微球蛋白通过线粒体和cGAS-STING途径激活巨噬细胞样细胞的模块化作用机制研究
Josefine Kofoed Corneliussen,Helena Borland Madsen,Nadia Thaulov Zelander et al.
Josefine Kofoed Corneliussen et al.
Beta-2-microglobulin (β2m) is a component of the major histocompatibility complex class I. β2m is released into cellular fluids in response to various stimuli, including pro-inflammatory cytokines. Elevated β2m levels have been found ass...
The NLRP3 Inflammasome in inflammatory diseases: Cellular dynamics and role in granuloma formation [0.03%]
NLRP3炎症小体在炎性疾病中的作用：细胞动力学及其在肉芽肿形成中的作用
Isadora M de Oliveira,Mariana M Chaves
Isadora M de Oliveira
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) and damage associated molecular patterns (DAMPs) through pattern recognition receptors (PRRs). Inflammasomes, cytoplasmic protein complexes, are activated in...