MEX3A activates the JAK-STAT pathway to suppress NK cell cytotoxicity and accelerate lung adenocarcinoma progression [0.03%]
MEX3A激活JAK-STAT通路抑制NK细胞毒性并加速肺腺癌进展
Jigui Peng,Haiqiang Yan,Wang Zhou et al.
Jigui Peng et al.
Background: Therapeutic potential of natural killer (NK) cells is recognized in treating lung adenocarcinoma (LUAD), but impairment of NK cell functions in various cancers weakens anti-tumor capabilities. Uncovering molec...
Curcumin mitigates systemic lupus erythematosus by suppressing double-negative T cells through cell apoptosis [0.03%]
姜黄素通过诱导细胞凋亡抑制双阴性T细胞从而缓解系统性红斑狼疮
Min Xu,Xiaoliu Li,Cheng Bao et al.
Min Xu et al.
Objective: Curcumin extracted from the rhizome of Curcuma longa has anti-inflammatory, antioxidant and antitumour properties. In previous studies, curcumin has been reported to have therapeutic effects on systemic lupus e...
A novel approach to hematopoietic stem cell transplantation: The effect of CMV infection and HLA genotypes on chimerism status in Egyptian patients [0.03%]
一种新的造血干细胞移植方法:CMV感染和HLA基因型对埃及患者嵌合状态的影响
Raghda Mohammed Ghorab,Hala Ahmed Talkhan,Asmaa Mohamed Abd ElGwad et al.
Raghda Mohammed Ghorab et al.
Several studies have investigated the association between HLA alleles and cytomegalovirus (CMV) infection following hematopoietic stem cell transplantation (HSCT). It was found that many HLA alleles were associated with increased rate of CM...
Polymorphonuclear myeloid-derived suppressor cells protect against hyperoxia-induced bronchopulmonary dysplasia in neonatal mice through suppression of excessive inflammatory response [0.03%]
多形核髓源性抑制细胞通过抑制过度炎症反应来预防新生小鼠高氧诱导的支气管肺发育不良
Boshi Yu,Guixuan Hong,Yubai Li et al.
Boshi Yu et al.
Background: Bronchopulmonary dysplasia (BPD), which primarily affects premature infants, is characterized by impaired lung development, reduced alveolarization, and chronic inflammation, leading to long-term respiratory c...
Gliadin amplifies the macrophage response triggered by stressed beta cells [0.03%]
胶质蛋白可放大应激β细胞诱发的巨噬细胞反应
Tina Zenia Jørgensen,Knud Josefsen,Signe Stentoft Dissing et al.
Tina Zenia Jørgensen et al.
In humans, a gluten-free diet can slow disease progression and improve clinical outcome in newly diagnosed type 1 diabetes patients. In NOD mice, the incidence of autoimmune diabetes is influenced by both beta cell activity and gluten. Here...
Shuaiyi Li,Xiaohui Zhou,Shidi Yu et al.
Shuaiyi Li et al.
The pathogenesis of autoimmune diseases (AIDs) is complex and their etiology remains unclear, with multiple cell types involved in the disease progression. Macrophages, as a crucial immune cell population in AIDs, play a pivotal role in mai...
Aerobic exercise activates let-7e-5p through TP73-AS1 to inhibit the HMGB1/RAGE axis and alleviate asthma airway inflammation and remodeling [0.03%]
有氧运动通过TP73-AS1激活let-7e-5p抑制HMGB1/RAGE轴并缓解哮喘气道炎症和重塑
Dan Wang,Jing Zhao,Chunyan Yang et al.
Dan Wang et al.
The rising incidence of asthma, a chronic respiratory condition, has been associated with the involvement of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in its pathogenesis. Nevertheless, there is a shortage of data pertaining to ...
"Mesenchymal stem cell-derived exosomes (MSC-exosomes) in hematology: From mechanisms to clinical breakthroughs" [0.03%]
造血干细胞来源的外泌体:从机制到临床突破
Irfan Ahmad,Ahmed Hussein,Bhavesh Kanabar et al.
Irfan Ahmad et al.
Mesenchymal stem cells (MSCs) offer promising therapy because they regulate the immune system and help repair tissues. However, challenges such as low cell survival rates, immune rejection, and ethical concerns related to their clinical use...
Corrigendum to "Modular activation of macrophage-like cells by beta-2-microglobulin via mitochondria and the cGAS-STING pathway" [Cell. Immunol. 413 (2025) 104962] [0.03%]
关于“β-2微球蛋白通过线粒体和cGAS-STING途径激活类似巨噬细胞的细胞”的勘误修正[cell. immunol. 413 (2025) 104962]
Josefine Kofoed Corneliussen,Helena Borland Madsen,Nadia Thaulov Zelander et al.
Josefine Kofoed Corneliussen et al.
Published Erratum
Cellular immunology. 2025 Jun 7:104984. DOI:10.1016/j.cellimm.2025.104984 2025
PGC1α-mediated mitochondrial fitness promotes Treg cell differentiation [0.03%]
PGC1α介导的线粒体健壮性促进Treg细胞分化
Luis Eduardo Alves Damasceno,Gabriel Alberto de Carvalho Barbosa,Tim Sparwasser et al.
Luis Eduardo Alves Damasceno et al.
Regulatory T (Treg) cells play a critical role in the maintenance of immune tolerance to self-antigens and suppression of excessive immune responses. They employ a distinct metabolic profile from other CD4 T cell subsets to support their di...