The relationship between maternal adiposity during pregnancy and toddler ADHD symptoms is mediated by gestational inflammation [0.03%]
孕妇肥胖与妊娠期炎症介导的幼儿多动症症状之间的关系
Hanna C Gustafsson,Geoffrey A Dunn,Jennifer M Loftis et al.
Hanna C Gustafsson et al.
Background: Increased adiposity during pregnancy is associated with increased risk for child attention-deficit/hyperactivity disorder (ADHD), though few studies have examined the mechanisms responsible for conveying this ...
Neuroimmune lipidome dysregulation in major depressive disorder: A meta-analysis of peripheral endocannabinoid and N-acylethanolamine signaling [0.03%]
抑郁症患者的神经免疫脂质组失调：外周内源大麻素和N-乙醇胺信号通路的荟萃分析
Muhammad Yaseen,Wei-Jen Chen,Jane Pei-Chen Chang et al.
Muhammad Yaseen et al.
Major depressive disorder (MDD) is a prevalent psychiatric condition characterized by substantial biological heterogeneity. Evidence suggests that the endocannabinoid system (ECS), which regulates stress responses, emotional processing, and...
Sex-associated neuroinflammatory and astrocytic responses in amyotrophic lateral sclerosis: evidence from clinical cohorts and a TDP-43 N390D mouse model [0.03%]
系统性红斑狼疮免疫紊乱的遗传结构研究：基于东亚人群GWAS数据的多层次元分析
Wenfei Yu,Bing Zhao,Mingjie Ma et al.
Wenfei Yu et al.
Background: Sex differences are increasingly recognized as important modifiers of neuroimmune processes in neurodegenerative disorders. However, the sex-associated clinical phenotypes and underlying neuroinflammatory mech...
Glymphatic influx is not drainage: Interpreting AQP4-mediated POCD [0.03%]
甘淋巴系统流入不是引流：解读AQP4介导的POCD
Kaiyuan Zhang,Fuyou Guo
Kaiyuan Zhang
Reinmar Hager
Reinmar Hager
Cell adhesion molecules in traumatic brain injury: Orchestrating leukocyte infiltration, BBB disruption, and neuroinflammation [0.03%]
细胞粘附分子在创伤性脑损伤中的作用：调控白细胞浸润、血脑屏障破坏和神经炎症
Thalia Barrios Lizon,Ramdhan Russell,Yemin A Poovanthodi et al.
Thalia Barrios Lizon et al.
Cell adhesion molecules (CAMs) are essential regulators of tissue architecture, inflammation, and cellular signaling, mediating interactions between cells and their microenvironment. Major CAM families include intercellular adhesion molecul...
Mayssam Nehme,Margret Hund-Georgiadis,Esther Del Corral Beamonte et al.
Mayssam Nehme et al.
Introduction: More than 400 million individuals are estimated to have been affected by post-COVID condition or long COVID. This condition can lead to significantly decreased quality of life and increased individual and so...
Maternal immune activation induces sex-dependent metabolic, epigenetic and GABAergic trajectories in the hippocampus [0.03%]
母体免疫激活诱导出性别依赖的海马神经代谢、表观遗传及GABA能神经系统的变化轨迹
Francesca McEwan,James Dal Santo,Chiho Kambara et al.
Francesca McEwan et al.
Maternal immune activation (MIA) is associated with increased risk of neurodevelopmental disorders, including schizophrenia. Research demonstrates sex-specific responses to MIA, yet how MIA interacts with intrinsic sex differences during br...
Exosomes from bipolar disorder patients induce mania- and depression-like behaviors in mice via shared and distinct neuroimmune signatures [0.03%]
来自双相情感障碍患者的外泌体通过共享和不同的神经免疫特征诱导小鼠产生类似躁狂和抑郁的行为
Tongtong Yao,Liguo Li,Ya Su et al.
Tongtong Yao et al.
Bipolar disorder (BD) is a recurrent illness characterized by alternating episodes of mania and depression, yet the biological mechanisms underlying these oscillating states remain poorly understood. Exosomes, nanosized extracellular vesicl...