Microstructure of the corneal endothelial transition zone in different laboratory animals [0.03%]
不同实验动物角膜内皮过渡区微结构差异性研究
Jun Seob Lee,So Young Lee,Hee Seung Chin et al.
Jun Seob Lee et al.
Purpose: To compare the microstructure of the corneal endothelial transition zone in different laboratory animals. Methods: Flat-mount ...
Two novel non-coding single nucleotide variants in the DNase1 hypersensitivity site of PRDM13 causing North Carolina macular dystrophy in Korea [0.03%]
韩国发生北卡罗来纳州视网膜色素上皮营养不良的两个新型非编码单核苷酸变异体位于PRDM13的DNase I超敏感位点中
Yuri Seo,Kwangsic Joo,Junwon Lee et al.
Yuri Seo et al.
Purpose: Pathogenic variants in North Carolina macular dystrophy (NCMD) have rarely been reported in the East Asian population. Herein, we reported novel variants of NCMD in 2 Korean families. ...
EphB1 causes retinal damage through inflammatory pathways in the retina and retinal Müller cells [0.03%]
EphB1通过视网膜和视网膜Müller细胞的炎症通路引起视网膜损伤
Li Liu,Youde Jiang,Mohamed Al-Shabrawey et al.
Li Liu et al.
Purpose: To examine whether increased ephrin type-B receptor 1 (EphB1) leads to inflammatory mediators in retinal Müller cells. Methods: ...
Exosomal microRNAs as potential biomarkers and therapeutic targets in corneal diseases [0.03%]
外泌体微小RNA在角膜疾病中作为潜在生物标志物和治疗靶点的作用
Swati Arora,Nagendra Verma
Swati Arora
Exosomes are a subtype of extracellular vesicle (EV) that are released and found in almost all body fluids. Exosomes consist of and carry a variety of bioactive molecules, including genetic information in the form of microRNAs (miRNAs). miR...
Review
Molecular vision. 2024 Mar 15:30:92-106. DOI: 2024
The importance of the fourth Greek key motif of human γD-crystallin in maintaining lens transparency-the tale told by the tail [0.03%]
希腊钩状图案第四种模式对于人眼γD晶状体蛋白保持晶状体透明性的作用——由蛋白质C端尾巴的故事说起
VenkataPullaRao Vendra,Madhupreetha Thangapandian
VenkataPullaRao Vendra
Purpose: Congenital cataract affects 1-15 per 10,000 newborns worldwide, and 20,000-40,000 children are born every year with developmental bilateral cataracts. Mutations in the crystallin genes are known to cause congenit...
Impact of light-emitting diodes on visual cortex layer 5 pyramidal neurons (V1-L5PNs)-A rodent study [0.03%]
发光二极管对视觉皮层第五层锥体神经元的影响（V1-L5PNs）-一项啮齿动物研究
Nagarajan Theruveethi
Nagarajan Theruveethi
Purpose: Light-induced neural retinal insult leads to alterations in the visual cortex neurons. We examined light-induced neuronal alterations in the visual cortex layer 5 pyramidal neurons (V1-L5PNs) of adult male Wistar...
Clinical sequencing of the retinitis pigmentosa gene RPGR in over 1,000 cases of vision loss [0.03%]
RPGR基因临床序列在1000多例视力下降中的应用
Madhulatha Pantrangi,Julie Rath,Nicole Kaetterhenry et al.
Madhulatha Pantrangi et al.
RPGR pathogenic variants are the major cause of X-linked retinitis pigmentosa. Here, we report the results from 1,033 clinical DNA tests that included sequencing of RPGR. A total of 184 RPGR variants were identified: 78 pathogenic or likely...
Central subfield thickness of diabetic macular edema: Correlation with the aqueous humor proteome [0.03%]
糖尿病性黄斑水肿中心子字段厚度与房水蛋白质组的相关性研究
Lasse Jørgensen Cehofski,Kentaro Kojima,Natsuki Kusada et al.
Lasse Jørgensen Cehofski et al.
Purpose: Diabetic macular edema (DME) is a sight-threatening complication of diabetes. Consequently, studying the proteome of DME may provide novel insights into underlying molecular mechanisms. ...
Distribution of TGFBI variants in patients with early onset glaucoma [0.03%]
TGFBI变异体在早期发病性青光眼患者中的分布
Viney Gupta,Arnav Panigrahi,Bindu I Somarajan et al.
Viney Gupta et al.
Purpose: To describe a novel association of TGFBI variants with congenital glaucoma in a family with GAPO (growth retardation, alopecia, pseudoanodontia, and progressive optic atrophy) syndrome, as well as among other unr...
Case Reports
Molecular vision. 2023 Dec 26:29:365-377. DOI: 2023
Toll-like receptor-4 expression and oxidative stress in ocular rosacea [0.03%]
睑部玫瑰痤疮中 toll 样受体 4 的表达及氧化应激反应
Nilufer Yesilirmak,Neslihan Bukan,Busra Kurt et al.
Nilufer Yesilirmak et al.
Purpose: To investigate systemic and ocular toll-like receptor (TLR)-4 expression and its association with oxidative stress markers in ocular rosacea (OR). ...