Targeted sequencing with single-molecule molecular inversion probes highlights a gap in understanding the cause of Fuchs endothelial corneal dystrophy [0.03%]
单分子倒转探针靶向测序揭示了对Fuchs内皮角膜营养不良发病机制认识的不足
Bushra Alayed,Danah Albuainain,Salina Siddiqui et al.
Bushra Alayed et al.
Purpose: A trinucleotide repeat expansion in TCF4 is thought to cause Fuchs endothelial corneal dystrophy (FECD) in ~70% of European patients. In addition, strong evidence exists for the involvement of rare variants in CO...
Nanobacterial detection in aqueous humor and its effect on postphacoemulsification visual acuity among highly myopic patients [0.03%]
纳米细菌在眼用液态中的检测及其对后囊外摘除术的高近视患者的视力的影响
Xiaoli Wu,Yan Zhou,Fen Lan et al.
Xiaoli Wu et al.
This study aimed to investigate factors affecting visual outcomes after phacoemulsification in highly myopic patients with cataracts, based on the detection of nanobacteria (NB) in aqueous humor. Fifty highly myopic patients with cataracts ...
Analysis of retinal ganglion cell subtypes across six different inbred mouse strains [0.03%]
小鼠六个不同的近交系视网膜节细胞亚型分析
Su-Ting Lin,Fangyu Lin,Jiaxing Wang et al.
Su-Ting Lin et al.
Purpose: Retinal ganglion cells (RGCs) are the principal conduits responsible for propagating visual stimuli from the retina to visual centers in the brain. The loss of RGCs leads to visual deficits following trauma or in...
RNA interference to reduce Egr1 expression in rods delays retinal degeneration in a model of retinitis pigmentosa [0.03%]
RNA干扰沉默Egr1基因对视网膜色素变性模型小鼠棒状光感受器的保护作用
Luca Merolla,Antonia Fottner,Cornelia Imsand et al.
Luca Merolla et al.
Purpose: Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal diseases characterized by progressive photoreceptor degeneration. The early growth response-1 gene (Egr1) is an immediate-early gene implica...
Retinal ribbon synapses and the potential functional role of TIAM1: A structural and molecular perspective [0.03%]
视网膜带状突触及TIAM1蛋白的潜在功能作用：结构和分子角度分析
Martha Emil Adly
Martha Emil Adly
Purpose: Retinal and inner ear ribbon synapses are specialized sensory synapses characterized by synaptic ribbons, electron-dense and protein-rich structures that enable rapid and sustained neurotransmitter release. This review aims to exam...
Review
Molecular vision. 2026 Feb 25:32:131-141. DOI: 2026
Review: The role of microglia in diabetic retinopathy and its potential as a therapeutic target [0.03%]
微胶质细胞在糖尿病视网膜病变中的作用及其作为治疗靶点的潜力评审文章
Wen Liu,Jieyu Jiang,Wenwen Li et al.
Wen Liu et al.
Diabetic retinopathy (DR) is a common and severe complication of diabetes, which poses a serious threat to vision, and its pathogenesis is complex. Inflammatory response plays a crucial role in the progression of DR, but currently, anti-vas...
Review
Molecular vision. 2026 Feb 7:32:49-68. DOI: 2026
Molecular responses of human retinal pigment epithelial cells to ebolavirus VP24 [0.03%]
人类视网膜色素上皮细胞对埃博拉病毒VP24的分子反应
Liam M Ashander,Yuefang Ma,Genevieve F Oliver et al.
Liam M Ashander et al.
Purpose: Uveitis (inflammation inside the eye) is a disabling manifestation of the post-Ebola syndrome that affects 10% to 35% of individuals who survive the infection. Post-Ebola uveitis presents with diverse clinical fe...
Submacular tissue repair and fibrosis in neovascular macular degeneration: A predictable outcome secondary to a chronic age-related endotheliopathy [0.03%]
年龄相关内皮病慢性化的次视网膜组织修复和纤维化预测黄斑新生血管形成后的结果
Beatriz G Armendariz,David Kent
Beatriz G Armendariz
Fibrosis is strictly a histopathological term that refers to the replacement of functional tissue with permanent deposition of nonfunctional extracellular matrix (ECM), following an injury or disease, and can occur in any tissue in the body...
Review
Molecular vision. 2026 Jan 20:32:22-32. DOI: 2026
Exploring the molecular basis of microphthalmia and anophthalmia: Insights from an Egyptian cohort [0.03%]
探索小眼症和无眼症的分子基础：来自埃及队列的见解
Gehad Elmakkawy,Amira Nabil,Karim Nabil et al.
Gehad Elmakkawy et al.
Purpose: The aim of this study was to gain insight into the molecular spectrum of anophthalmia and microphthalmia (A/M) in the Egyptian population. Method...
Insight into genes responsible for cornea plana, megalocornea, keratoconus and brittle cornea syndrome [0.03%]
角膜平面、大角膜、角膜营养不良和脆弱角膜综合征发病基因的解析研究进展
Di Zhu,Yuxi Zheng,Yi Jiang et al.
Di Zhu et al.
Purpose: Inherited diseases characterized by abnormal corneal morphology include cornea plana, megalocornea, keratoconus and brittle cornea syndrome. This study aims to investigate genes responsible for these diseases. ...