Molecular genetic analysis of R124H TGFBIp in one family Avellino corneal dystrophy [0.03%]
Avellino角膜营养不良家系中R124HTGFBIp的分子遗传分析
Yuluo Huang,Ming Liu,Huayi Lu et al.
Yuluo Huang et al.
Purpose: The mutation of R124H in TGFBIp causes Avellino corneal dystrophy (ACD, GCD II). However, the molecular mechanisms of ACD caused by the p. R124H mutation are not well understood. In our research, we aimed to expl...
Human lens epithelial cells induce the inflammatory response when placed into the lens capsular bag model of posterior capsular opacification [0.03%]
人眼晶状体上皮细胞在后囊下混浊模型的眼晶状体囊袋中引起炎症反应
Samuel G Novo,Adam P Faranda,Justin C D&#x;Antin et al.
Samuel G Novo et al.
Purpose: Cataracts are typically treated by phacoemulsification followed by intraocular lens implantation. Studies of mouse models of cataract surgery have revealed that lens epithelial cells rapidly remodel their transcr...
Complex genomic rearrangement with deletion of PITX2 in a Chinese family with Axenfeld-Rieger syndrome: A case report and literature review [0.03%]
Axenfeld-Rieger综合症中国家系中PITX2基因缺失所致的复杂染色体重排：病例报告及文献回顾
Zhen Jiang,Ya Zhang,Liqin Wang et al.
Zhen Jiang et al.
Purpose: This study identified the genetic causes of Axenfeld-Rieger syndrome (ARS) in a Chinese family and evaluated their clinical phenotype and clinical treatment. ...
Review
Molecular vision. 2024 Dec 31:30:466-476. DOI: 2024
Salidroside ameliorates diabetic retinopathy and Müller cell inflammation via the PI3K/Akt/GSK-3β/NF- [0.03%]
山娑罗苷通过PI3K/Akt/GSK-3β/NF-κB信号通路改善糖尿病视网膜病变及Müller细胞炎症反应
Zhen Feng,Yang Yang,Cai-Xing Shi et al.
Zhen Feng et al.
Purpose: To determine whether salidroside (SAL) modulates inflammatory cytokines in rat retinal Müller cells (rMC-1) in a hyperglycemic environment by investigating the anti-inflammatory mechanisms of SAL in vitro and in...
Assessment of anterior scleral thickness in myopes and emmetropes using anterior segment optical coherence tomography [0.03%]
应用眼前段光学相干断层扫描评估近视眼和正视眼前房巩膜厚度
Zhi-Liang Li,Qi Xiong,Shun-Cheng Cai et al.
Zhi-Liang Li et al.
Purpose: To investigate the differences in anterior scleral thickness (AST) among the refractive statuses of Chinese adults aged 18-35. Methods: ...
Sulforaphane inhibits TGF-β-induced fibrogenesis and inflammation in human Tenon's fibroblasts [0.03%]
萝卜硫素抑制转化生长因子诱导的小梁网成纤维细胞纤维化和炎症反应
Yang Liu,Yangbin Huang,Zihan Guo et al.
Yang Liu et al.
Purpose: Subconjunctival fibrosis is the main cause of failure after glaucoma filtration surgery. We explored the effects of sulforaphane (SFN) on the conversion of human Tenon's fibroblasts (HTFs) into myofibroblasts, tr...
Increased inflammatory mediators in the ocular surface tissue in keratoconus [0.03%]
角膜扩张症眼表组织炎症介质增加
Albert Santos,José A P M Filho,Marcos A Cenedeze et al.
Albert Santos et al.
Purpose: This study aimed to characterize the inflammatory mediators present in the tear film of patients with keratoconus (KC). It also aimed to investigate the gene expression of these mediators in corneal epithelial ce...
Complement C3 is downregulated following ranibizumab intervention in experimental central retinal vein occlusion [0.03%]
补体C3在实验性中央视网膜静脉阻塞雷珠单抗干预后的下调表达
Lasse Jørgensen Cehofski,Anders Kruse,Mads Odgaard Mæng et al.
Lasse Jørgensen Cehofski et al.
Purpose: Ranibizumab is a frequently used inhibitor of vascular endothelial growth factor (VEGF) in the treatment of macular edema following central retinal vein occlusion (CRVO). Studying proteins that mediate the benefi...
Clinically correlated dose of the amniotic membrane extract is superior to its transplantation in corneal wound healing [0.03%]
临床相关的羊膜提取物剂量优于其移植促进角膜伤口愈合
Ilayda Korkmaz,Meltem Kocamanoglu,Mehmet Gurdal et al.
Ilayda Korkmaz et al.
Purpose: This study investigates the superiority of sterile lyophilized amniotic membrane extract (AME) prepared at a clinically correlated dose over amniotic membrane transplantation (AMT) in an experimental corneal woun...
A potential novel role of the R36P mutation in CRYGD in congenial cataract [0.03%]
CRYGD中R36P突变在先天性白内障中的潜在新作用
Chen Tan,Xueting Yu,Junyi Chen et al.
Chen Tan et al.
Purpose: Congenital cataract is an important cause of visual impairment in childhood. Our previous study reported that the c.110G>C (p.R36P) mutation in the γD-crystallin gene (CRYGD) was associated with congenital catar...