Guitong Ye,Yuan Zhang,Kezhe Chen et al.
Guitong Ye et al.
Purpose: Primate eyes feature a physiologic accommodative system identical to that of humans. Nonetheless, their biometric changes before and after cycloplegia have not been investigated. In this study, we aimed to evalua...
Konstantin Y Gushansky,Petteri Karesvuo,Raimo Tuuminen
Konstantin Y Gushansky
Purpose: To evaluate the association between suboptimal glycemic control and central macular thickness in central retinal vein occlusion patients over a 1-year follow-up period. ...
Intraocular pressure distribution in old and young cynomolgus monkeys following general anesthesia and mydriasis [0.03%]
Jinan Zhan,Zhidong Li,Guitong Ye et al.
Jinan Zhan et al.
Purpose: To investigate the intraocular pressure (IOP) distribution of cynomolgus monkeys in different age groups after anesthesia and mydriasis. Methods:...
Genetic phenotypic characteristics and inheritance patterns of patients with achromatopsia at a large academic institution and a review of the literature and gene therapies [0.03%]
Sanjana Molleti,Pedro F Monsalve,Richard N Sather rd et al.
Sanjana Molleti et al.
Purpose: Achromatopsia (ACHM) is a cone dysfunction syndrome associated with low color vision, photophobia, and congenital nystagmus. Pathogenic variants in the CNGA3 and CNGB3 genes are the most common causes of ACHM. Id...
Review
Molecular vision. 2025 Nov 12:31:454-461. DOI: 2025
Inhibition of sortilin reduces neuronal and vascular damage after ischemia/reperfusion through reduced inflammatory and autophagy actions in retinal Müller cells [0.03%]
Li Liu,Youde Jiang,Jena J Steinle
Li Liu
Purpose: Our goal was to explore whether inhibition of sortilin could protect the retina against ischemia/reperfusion (I/R) damage, as well as explore whether this inhibition could reduce inflammatory mediators in retinal...
System biology analysis reveals that Grm6 is associated with glutamate accumulation-induced scotopic vision impairment in diabetic mice [0.03%]
Ying Lian,Yanpu Zhao,Xiaoyu Yang et al.
Ying Lian et al.
Purpose: Scotopic vision impairment as an early event is found in diabetic retinopathy. However, the underlying mechanisms behind hyperglycemia-induced scotopic vision impairment remain unclear. This study aims to identif...
Ferroptosis related genes in retinopathy of prematurity: Screening for potential pharmacological targets [0.03%]
Qiujuan Liao,Suyu Liu,Liqing Wei et al.
Qiujuan Liao et al.
Purpose: To elucidate the molecular mechanisms of retinopathy of prematurity (ROP) and identify potential drug targets for its treatment based on bioinformatics analysis. ...
Monocyte/macrophage-derived IL-15 activates STAT5 to trigger the EFNA1/NCOA2-positive feedback loop, facilitating retinal angiogenesis in high-glucose environments [0.03%]
Lixin Zhang,Yan Guo
Lixin Zhang
Purpose: Diabetic retinopathy (DR) is of the most prevalent complications among diabetic patients. The potential role of interleukin 15 (IL-15) in modulating immune cell function and angiogenesis has drawn considerable at...
Nitazoxanide reduced inflammatory markers and mitochondrial changes in human retinal endothelial cells grown in high glucose [0.03%]
Youde Jiang,Neeraja Purandare,Li Liu et al.
Youde Jiang et al.
Purpose: To determine whether nitazoxanide (NZT) can increase mitochondrial nuclear retrograde regulator 1 (MNRR1) in retinal endothelial cells (RECs) grown in normal or high glucose and thereby reduce inflammation. ...
Deciphering the genetic basis of inherited retinal dystrophies via whole-exome sequencing in a Turkish cohort [0.03%]
Zulal Keles,Ozlem Ural Fatihoglu,Ziya Ayhan et al.
Zulal Keles et al.
Purpose: Inherited retinal dystrophies (IRDs) encompass a genetically and clinically heterogeneous group of disorders, with over 300 genes currently implicated. Early and precise genetic diagnosis is critical for advancin...