Evaluation of the Algerbrush II rotating burr as a tool for inducing ocular surface failure in a mouse model [0.03%]
Algerbrush II旋转钻头作为诱导小鼠模型眼表失败的工具的评估
Athar Shadmani,Trent Jarin,Xiang Qi Meng et al.
Athar Shadmani et al.
Purpose: The Algerbrush II has been widely used to induce corneal and limbal injuries in animal models. The extent of injury varies with the duration of exposure, pressure from the placement of the burr, and the size of t...
Changes in glutamate and glutamine distributions in the retinas of cystine/glutamate antiporter knockout mice [0.03%]
胱氨酸/谷氨酸抗转运蛋白敲除小鼠视网膜中谷氨酸和谷氨酰胺分布的变化
Luis J Knight,Renita M Martis,Paul J Donaldson et al.
Luis J Knight et al.
Purpose: The cystine/glutamate antiporter is involved in the export of intracellular glutamate in exchange for extracellular cystine. Glutamate is the main neurotransmitter in the retina and plays a key metabolic role as ...
Oxidative stress-induced temporal activation of ERK1/2 phosphorylates coreceptor of Wnt/β-catenin for myofibroblast formation in human lens epithelial cells [0.03%]
氧化应激诱导的ERK1/2磷酸化Wnt / β-连环蛋白核心受体在人晶状体上皮细胞中促进成肌纤维细胞样转型的发生
Zaoxia Guo,Xiaopan Ma,Xi Chen et al.
Zaoxia Guo et al.
Purpose: Posterior capsular opacification (PCO) is the most common complication postcataract surgery, and its underlying mechanisms involve epithelial-mesenchymal transition (EMT) of remnant lens epithelial cells (LECs) i...
Investigation of the antioxidant effect of Chrysin in an experimental cataract model created in chick embryos [0.03%]
黄酮在鸡胚胎白内障模型中抗氧效果的研究
Gülan Albaş Kurt,Tolga Ertekin,Emre Atay et al.
Gülan Albaş Kurt et al.
Purpose: Cataract, which occurs as a result of lens opacification, is one of the most common causes of vision loss. In the literature, deterioration of the antioxidant system due to the increase in reactive oxygen species...
GPR143 mutations in an X-linked infantile nystagmus syndrome cohort in Southeast China [0.03%]
中国东南部X连锁婴儿型眼球震颤综合征队列中的GPR143突变
Jingling Xu,Yihan Zheng,Lulu Cheng et al.
Jingling Xu et al.
Purpose: Infantile nystagmus syndrome (INS), or congenital nystagmus (CN), refers to a group of ocular motor disorders characterized by rapid to-and-fro oscillations of the eyes. GPR143 is the causative gene of ocular alb...
The impact of early RPE cell junction loss on VEGF, Ang-2, and TIMP secretion in vitro [0.03%]
视网膜色素上皮细胞连接丧失对体外VEGF、Ang-2和TIMP分泌的影响
Chase Paterson,Jamen Cannon,Elizabeth Vargis
Chase Paterson
Purpose: The retinal pigment epithelium (RPE) is an important tissue for maintaining a healthy retina. Retinal pigment epithelial cells help regulate nutrient transport to photoreceptors and are heavily pigmented to preve...
PET imaging of retinal inflammation in mice exposed to blue light using [18F]-DPA-714 [0.03%]
使用[18F]-DPA-714对蓝光暴露小鼠视网膜炎症进行正电子发射断层成像(PET)
Yuan Chen,Yixiang Zhou,Xue Zhu et al.
Yuan Chen et al.
Purpose: Positron emission tomography (PET) is widely used in high-precision imaging, which may provide a simple and noninvasive method for the detection of pathology and therapeutic effects. [18F]-DPA-714 is a second-gen...
Collagen crosslinking impacts stromal wound healing and haze formation in a rabbit phototherapeutic keratectomy model [0.03%]
胶原交联影响兔phototherapeutic keratectomy模型中基质伤口愈合和雾状物形成
Bret A Moore,Iman Jalilian,Soohyun Kim et al.
Bret A Moore et al.
Purpose: The purpose of this study was to evaluate the elastic modulus, keratocyte-fibroblast-myocyte transformation, and haze formation of the corneal stroma following combined phototherapeutic keratectomy (PTK) and epit...
USH2A mutational spectrum causing syndromic and non-syndromic retinal dystrophies in a large cohort of Mexican patients [0.03%]
墨西哥大型患者队列中导致视网膜营养不良的USH2A变异类型及谱系
Vianey Ordoñez-Labastida,Oscar F Chacon-Camacho,Victor R Lopez-Rodriguez et al.
Vianey Ordoñez-Labastida et al.
Background: Mutations in the USH2A gene are the leading cause of both non-syndromic autosomal recessive retinitis pigmentosa (RP) and Usher syndrome, a syndromic form of RP characterized by retinal dystrophy and sensorine...
Genetic causes of inherited retinal diseases among Israeli Jews of Ethiopian ancestry [0.03%]
埃塞俄比亚后裔以色列犹太人遗传性视网膜疾病的基因病因学研究
Tamar Ben Yosef,Eyal Banin,Elana Chervinsky et al.
Tamar Ben Yosef et al.
Purpose: This study sought to describe the phenotype frequency and genetic basis of inherited retinal diseases (IRDs) among a nationwide cohort of Israeli Jewish patients of Ethiopian ancestry. ...