The impact of early RPE cell junction loss on VEGF, Ang-2, and TIMP secretion in vitro [0.03%]
视网膜色素上皮细胞连接丧失对体外VEGF、Ang-2和TIMP分泌的影响
Chase Paterson,Jamen Cannon,Elizabeth Vargis
Chase Paterson
Purpose: The retinal pigment epithelium (RPE) is an important tissue for maintaining a healthy retina. Retinal pigment epithelial cells help regulate nutrient transport to photoreceptors and are heavily pigmented to preve...
PET imaging of retinal inflammation in mice exposed to blue light using [18F]-DPA-714 [0.03%]
使用[18F]-DPA-714对蓝光暴露小鼠视网膜炎症进行正电子发射断层成像(PET)
Yuan Chen,Yixiang Zhou,Xue Zhu et al.
Yuan Chen et al.
Purpose: Positron emission tomography (PET) is widely used in high-precision imaging, which may provide a simple and noninvasive method for the detection of pathology and therapeutic effects. [18F]-DPA-714 is a second-gen...
Collagen crosslinking impacts stromal wound healing and haze formation in a rabbit phototherapeutic keratectomy model [0.03%]
胶原交联影响兔phototherapeutic keratectomy模型中基质伤口愈合和雾状物形成
Bret A Moore,Iman Jalilian,Soohyun Kim et al.
Bret A Moore et al.
Purpose: The purpose of this study was to evaluate the elastic modulus, keratocyte-fibroblast-myocyte transformation, and haze formation of the corneal stroma following combined phototherapeutic keratectomy (PTK) and epit...
USH2A mutational spectrum causing syndromic and non-syndromic retinal dystrophies in a large cohort of Mexican patients [0.03%]
墨西哥大型患者队列中导致视网膜营养不良的USH2A变异类型及谱系
Vianey Ordoñez-Labastida,Oscar F Chacon-Camacho,Victor R Lopez-Rodriguez et al.
Vianey Ordoñez-Labastida et al.
Background: Mutations in the USH2A gene are the leading cause of both non-syndromic autosomal recessive retinitis pigmentosa (RP) and Usher syndrome, a syndromic form of RP characterized by retinal dystrophy and sensorine...
Genetic causes of inherited retinal diseases among Israeli Jews of Ethiopian ancestry [0.03%]
埃塞俄比亚后裔以色列犹太人遗传性视网膜疾病的基因病因学研究
Tamar Ben Yosef,Eyal Banin,Elana Chervinsky et al.
Tamar Ben Yosef et al.
Purpose: This study sought to describe the phenotype frequency and genetic basis of inherited retinal diseases (IRDs) among a nationwide cohort of Israeli Jewish patients of Ethiopian ancestry. ...
Encephalopsin (OPN3) is required for normal refractive development and the GO/GROW response to induced myopia [0.03%]
脑皮质蛋白3（OPN3）要求正常屈光发育和诱导近视的GO / GROW响应
Courtney Linne,Khine Yin Mon,Shane D&#x;Souza et al.
Courtney Linne et al.
Purpose: Myopia, or nearsightedness, is the most common form of refractive error and is increasing in prevalence. While significant efforts have been made to identify genetic variants that predispose individuals to myopia...
Basement membrane regeneration and TGF-β1 expression in rabbits with corneal perforating injury [0.03%]
家兔角膜穿通伤的基底膜再生及TGF-β1表达
Na Meng,Jinling Wu,Jingjing Chen et al.
Na Meng et al.
Purpose: To evaluate the relationship between basement membrane (BM) regeneration and the spatiotemporal expression of TGF-β1 during wound healing in rabbits with corneal perforating injury. ...
The retina-specific basigin isoform does not induce IL-6 expression in mouse monocytes [0.03%]
视网膜特异性基格素等位基因不会诱导小鼠单核细胞白细胞介素-6的表达
Abigail D Solstad,Josephine M Brown,Judith D Ochrietor
Abigail D Solstad
Purpose: Basigin gene products are positioned on adjacent cell types in the neural retina and are thought to compose a lactate metabolon important for photoreceptor cell function. The Ig0 domain of basigin isoform 1 (basi...
Identification of a novel partial deletion of STS associated with pre-Descemet corneal dystrophy and X-linked ichthyosis [0.03%]
与前Descemet层角膜营养不良和X连锁鱼鳞病相关的STS新部分缺失鉴定
Dominic Williams,Onyinye Onyia,Doug D Chung et al.
Dominic Williams et al.
Purpose: Pre-Descemet corneal dystrophy (PDCD) with X-linked ichthyosis (XLI) is associated with mutations in or deletions of the steroid sulfatase gene (STS). As only three cases of genetically confirmed PDCD associated ...
Corneal epithelial basement membrane assembly is mediated by epithelial cells in coordination with corneal fibroblasts during wound healing [0.03%]
角膜上皮基底膜的构建在角膜伤口愈合过程中由上皮细胞和角膜成纤维细胞协调完成
Thomas Michael Shiju,Lycia Pedral Sampaio,Guilherme S L Hilgert et al.
Thomas Michael Shiju et al.
Purpose: To understand which cell types, either alone or in combination, contribute to the assembly of the epithelial basement membrane (BM) during corneal wound healing. ...