Angeleen Fleming,Ana Lopez,Matea Rob et al.
Angeleen Fleming et al.
Autophagies describe a set of processes in which cells degrade their cytoplasmic contents via various routes that terminate with the lysosome. In macroautophagy (the focus of this review, henceforth autophagy), cytoplasmic contents, includi...
Brett J Kagan,Forough Habibollahi,Brad Watmuff et al.
Brett J Kagan et al.
Harnessing intelligence from brain cells in vitro requires a multidisciplinary approach integrating wetware, hardware, and software. Wetware comprises the in vitro brain cells themselves, where differentiation from induced pluripotent stem ...
Targeting the TRPM4 Channel for Neurologic Diseases: Opportunity and Challenge [0.03%]
针对神经疾病的TRPM4通道的药物开发：机遇与挑战
Gayathri Rajamanickam,Zhenyu Hu,Ping Liao
Gayathri Rajamanickam
As a monovalent cation channel, the transient receptor potential melastatin 4 (TRPM4) channel is a unique member of the transient receptor potential family. Abnormal TRPM4 activity has been identified in various neurologic disorders, such a...
The mind-machine connection: adaptive information processing and new technologies promoting mental health in older adults [0.03%]
心灵与机器的连接：适应性信息处理及促进老年人精神健康的新兴技术
S S Magalhães,A M Lucas-Ochoa,A M Gonzalez-Cuello et al.
S S Magalhães et al.
The human brain demonstrates an exceptional adaptability, which encompasses the ability to regulate emotions, exhibit cognitive flexibility, and generate behavioral responses, all supported by neuroplasticity. Brain-computer interfaces (BCI...
Microglial Regulation of Neural Networks in Neuropsychiatric Disorders [0.03%]
小胶质细胞对神经精神疾病中神经网络的调节作用
Zi-Lin Cao,Li-Xia Zhu,Hong-Mei Wang et al.
Zi-Lin Cao et al.
Microglia serve as vital innate immune cells in the central nervous system, playing crucial roles in the generation and development of brain neurons, as well as mediating a series of immune and inflammatory responses. The morphologic transi...