Adult Hippocampal Neurogenesis in the Human Brain: Updates, Challenges, and Perspectives [0.03%]
人脑成人海马神经发生的更新、挑战与展望
Sophie Simard,Natalie Matosin,Naguib Mechawar
Sophie Simard
The existence of neurogenesis in the adult human hippocampus has been under considerable debate within the past three decades due to the diverging conclusions originating mostly from immunohistochemistry studies. While some of these reports...
Gustav Oppenheim (1882-1937) and the Discovery of Cerebral Amyloid Angiopathy [0.03%]
古斯塔夫·奥彭海姆(1882-1937)与脑淀粉样血管病的发现
Anthony Maurice Ness,Judd Aiken
Anthony Maurice Ness
The discovery of cerebral amyloid angiopathy (CAA) is frequently attributed to Dr. Gustav Oppenheim-a man who has been largely passed over in history. Oppenheim's clinical and neuropathologic research covered a variety of disorders, but his...
Jian Meng,Lingliang Zhang,Yun-Wu Zhang
Jian Meng
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder with onset in childhood. The molecular mechanisms underlying ASD have not yet been elucidated completely. Evidence has emerged to support a link between mi...
Pengyu Zong,Nicholas Legere,Jianlin Feng et al.
Pengyu Zong et al.
Glutamate excitotoxicity is a central mechanism contributing to cellular dysfunction and death in various neurological disorders and diseases, such as stroke, traumatic brain injury, epilepsy, schizophrenia, addiction, mood disorders, Hunti...
Neuron-Astrocyte Interactions and Circadian Timekeeping in Mammals [0.03%]
神经元-星形胶质细胞相互作用与哺乳动物的昼夜节律时钟功能
Nicola J Smyllie,Michael H Hastings,Andrew P Patton
Nicola J Smyllie
Almost every facet of our behavior and physiology varies predictably over the course of day and night, anticipating and adapting us to their associated opportunities and challenges. These rhythms are driven by endogenous biological clocks t...
Four Streams Within the Prefrontal Cortex: Integrating Structural and Functional Connectivity [0.03%]
前额叶皮层的四个功能区：整合结构和功能连接性
Dorit Ben Shalom,Georgios P Skandalakis
Dorit Ben Shalom
Merging functional evidence derived from studies of autism spectrum disorder and attention-deficit/hyperactivity disorder converges in four neural streams of the prefrontal cortex, hence suggesting a model of information processing through ...
Irene Martínez-Gallego,Antonio Rodríguez-Moreno
Irene Martínez-Gallego
Brain plasticity is the ability of the nervous system to change its structure and functioning in response to experiences. These changes occur mainly at synaptic connections, and this plasticity is named synaptic plasticity. During postnatal...