Computed Optical Interferometric Imaging: Methods, Achievements, and Challenges [0.03%]
计算光学干涉成像：方法、成就与挑战
Fredrick A South,Yuan-Zhi Liu,P Scott Carney et al.
Fredrick A South et al.
Three-dimensional high-resolution optical imaging systems are generally restricted by the trade-off between resolution and depth-of-field as well as imperfections in the imaging system or sample. Computed optical interferometric imaging is ...
Optical Coherence Tomography for Brain Imaging and Developmental Biology [0.03%]
用于脑 imaging 和发育生物学的光学 coherence tomography
Jing Men,Yongyang Huang,Jitendra Solanki et al.
Jing Men et al.
Optical coherence tomography (OCT) is a promising research tool for brain imaging and developmental biology. Serving as a three-dimensional optical biopsy technique, OCT provides volumetric reconstruction of brain tissues and embryonic stru...
Single-Molecule Tracking and Its Application in Biomolecular Binding Detection [0.03%]
单分子跟踪及其在生物分子结合检测中的应用
Cong Liu,Yen-Liang Liu,Evan P Perillo et al.
Cong Liu et al.
In the past two decades significant advances have been made in single-molecule detection, which enables the direct observation of single biomolecules at work in real time and under physiological conditions. In particular, the development of...
Infrared Methods for Assessment of the Activity of Natural Enamel Caries Lesions [0.03%]
红外线评估天然牙釉质龋损活动性的方法
Robert C Lee,Michal Staninec,Oanh Le et al.
Robert C Lee et al.
New diagnostic methods are needed for the accurate assessment of caries lesion activity to establish the need for surgical treatment. Detection of the highly mineralized surface layer that forms near the surface of the lesions as a result o...
Cocaine-Induced Abnormal Cerebral Hemodynamic Responses to Forepaw Stimulation Assessed by Integrated Multi-wavelength Spectroimaging and Laser Speckle Contrast Imaging [0.03%]
整合多波长光谱成像和激光散斑对比度成像评估可卡因诱导的前爪刺激异常脑血流动力学反应
Wei Chen,Kicheon Park,Nora Volkow et al.
Wei Chen et al.
Simultaneous imaging of cerebral hemodynamic changes in response to functional activation during drug intoxication provides a valuable strategy to assess cocaine induced neurovascular dysfunction. However, this requires tools with sufficien...
Enhancement of ARROW Photonic Device Performance via Thermal Annealing of PECVD-based SiO2 Waveguides [0.03%]
热退火改善PECVD硅片波导的ARROW光子器件性能
J W Parks,T A Wall,H Cai et al.
J W Parks et al.
Silicon-based optofluidic devices are very attractive for applications in biophotonics and chemical sensing. Understanding and controlling the properties of their dielectric waveguides is critical for the performance of these chips. We repo...
Flexible Plasmonic Sensors [0.03%]
柔性等离激元传感器
Daniel Shir,Zachary S Ballard,Aydogan Ozcan
Daniel Shir
Mechanical flexibility and the advent of scalable, low-cost, and high-throughput fabrication techniques have enabled numerous potential applications for plasmonic sensors. Sensitive and sophisticated biochemical measurements can now be perf...
Noncontact Elastic Wave Imaging Optical Coherence Elastography for Evaluating Changes in Corneal Elasticity Due to Crosslinking [0.03%]
无需接触的弹性波成像光学相干弹性图成像评价交联引起角膜弹性变化
Manmohan Singh,Jiasong Li,Srilatha Vantipalli et al.
Manmohan Singh et al.
The mechanical properties of tissues can provide valuable information about tissue integrity and health and can assist in detecting and monitoring the progression of diseases such as keratoconus. Optical coherence elastography (OCE) is a ra...
Signal-to-noise Enhancement in Optical Detection of Single Viruses with Multi-spot Excitation [0.03%]
多点激发增强单个病毒光学检测信噪比研究
Damla Ozcelik,Matthew A Stott,Joshua W Parks et al.
Damla Ozcelik et al.
We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio (SNR) achieved by multi-spot excitation in liquid-core anti-resonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguide...
Surgical Guidance via Multiplexed Molecular Imaging of Fresh Tissues Labeled with SERS-Coded Nanoparticles [0.03%]
用于手术引导的SERS编码纳米颗粒标记新鲜组织的多重分子成像
Yu Wang,Soyoung Kang,Josh D Doerksen et al.
Yu Wang et al.
The imaging of dysregulated cell-surface receptors (or biomarkers) is a potential means of identifying the presence of cancer with high sensitivity and specificity. However, due to heterogeneities in the expression of protein biomarkers in ...