Validation of the Linearity in Image Reconstruction Methods for Speckle Contrast Optical Tomography [0.03%]
斑点对比度光学层析成像中图像重建方法线性验证的研究
Alexander C Howard,Byungchan Kim,Laura Carlton et al.
Alexander C Howard et al.
Speckle contrast optical spectroscopy (SCOS) is an optical technique capable of measuring human cerebral blood flow and brain function non-invasively. Its tomographic extension, speckle contrast optical tomography (SCOT), can provide blood ...
Mitchell B Robinson,Marco Renna,Nikola Otic et al.
Mitchell B Robinson et al.
In this work, we present an enhanced diffuse correlation spectroscopy (DCS) method called pathlength-selective, interferometric DCS (PaLS-iDCS), which uses pathlength-specific coherent gain to improve both the sensitivity to deep tissue hem...
Super-Achromatic Rapid Scanning Microendoscope for Ultrahigh-Resolution OCT Imaging [0.03%]
一种用于超高分辨率OCT成像的超级消色差快速扫描微内窥镜
Danling Wang,Boyd V Hunter,Michael J Cobb et al.
Danling Wang et al.
Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendosco...
Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging [0.03%]
一种用于侧视穿刺组织成像的高性能高分辨精细OCT针头
Yicong Wu,Jiefeng Xi,Li Huo et al.
Yicong Wu et al.
Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (th...
High-Dose Photodynamic Therapy Increases Tau Protein Signals in Drosophila [0.03%]
高剂量光动力疗法增加果蝇的Tau蛋白信号
Jace A Willis,Vsevolod Cheburkanov,Vladislav V Yakovlev
Jace A Willis
Amyloid-Detection and imaging of amyloid-β plaques (Aβ) has been a focus in the field of neurodegeneration (ND) due to the high correlation with Parkinson's and Alzheimer's diseases. Here, a novel approach is being proposed and developed ...
Nonlinear Imaging Histopathology: A Pipeline to Correlate Gold-Standard Hematoxylin and Eosin Staining With Modern Nonlinear Microscopy [0.03%]
非线性成像病理学：与现代非线性显微镜相关的金标准苏木精-伊红染色管道研究
Kayvan Forouhesh Tehrani,Jaena Park,Eric J Chaney et al.
Kayvan Forouhesh Tehrani et al.
Hematoxylin and eosin (H&E) staining, the century-old technique, has been the gold standard tool for pathologists to detect anomalies in tissues and diseases such as cancer. H&E staining is a cumbersome, time-consuming process that delays a...
Short-Wave Infrared Emitting Nanocomposites for Fluorescence-Guided Surgery [0.03%]
用于荧光引导手术的短波红外发射纳米复合材料
Carolina Bobadilla Mendez,Amber Gonda,Jay V Shah et al.
Carolina Bobadilla Mendez et al.
Fluorescence-guided surgery (FGS) is an emerging technique for tissue visualization during surgical procedures. Structures of interest are labeled with exogenous probes whose fluorescent emissions are acquired and viewed in real-time with o...
A Real-Time Fluorescence Feedback System for Infrared Laser Sealing of Blood Vessels [0.03%]
用于血液血管红外激光封合的实时荧光反馈系统
Woheeb M Saeed,Nathaniel M Fried
Woheeb M Saeed
This study explores UV light induced fluorescence from blood vessels for indicating successful infrared laser sealing of vascular tissues. A light emitting diode (LED) with center wavelength of 340 nm and 0.1 mW power was used with a Y-shap...
Low-cost compact optical spectroscopy and novel spectroscopic algorithm for point-of-care real-time monitoring of nanoparticle delivery in biological tissue models [0.03%]
低成本紧凑型光谱仪及新型光谱算法在生物组织模型中对纳米粒子传递的实时监测中的应用研究
Md Zahid Hasan,Jing Yan,Zhongchao Yi et al.
Md Zahid Hasan et al.
Objective: Real-time monitoring of nanoparticle delivery in biological models is essential to optimize nanoparticle-mediated therapies. However, few techniques are available for convenient real-time monitoring of nanopart...
Coherent anti-Stokes Raman scattering microspectroscopy: an emerging technique for non-invasive optical assessment of a local bio-nano-environment [0.03%]
相干反斯托克斯拉曼光谱显微技术——一种用于局部生物纳米环境光学非侵入评估的新兴技术
Anton D Shutov,Joseph T Harrington,Hanlin Zhu et al.
Anton D Shutov et al.
Raman spectroscopy provides a non-invasive, chemically-specific optical imaging of biological objects without relying on endogenous labels. Nonlinear Raman spectroscopy allows non-invasive imaging at much faster speed with an improved spati...